메뉴 건너뛰기




Volumn 42, Issue 7, 2003, Pages 793-800

PnTx4-3, a new insect toxin from Phoneutria nigriventer venom elicits the glutamate uptake inhibition exhibited by PhTx4 toxic fraction

Author keywords

Glutamate uptake; Insect toxin; Phoneutria nigriventer

Indexed keywords

GLUTAMIC ACID; INSECT VENOM; NEUROTOXIN; NEUROTOXIN PNTX4 3; UNCLASSIFIED DRUG;

EID: 1642452826     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2003.10.009     Document Type: Article
Times cited : (20)

References (37)
  • 1
    • 0024562287 scopus 로고
    • Two classes of channel-specific toxins from funnel web spider venom
    • Adams M.E., Herold E.E., Venena V.J. Two classes of channel-specific toxins from funnel web spider venom. J. Comp. Physiol. A164:1989;333-342.
    • (1989) J. Comp. Physiol. , vol.164 , pp. 333-342
    • Adams, M.E.1    Herold, E.E.2    Venena, V.J.3
  • 2
    • 0025055598 scopus 로고
    • Omega-agatoxins: Novel calcium channel antagonists of two subtypes from funnel web spider (Agelenopsis aperta)
    • Adams M.E., Bindokas V.P., Hasegawa L., Venema V.J. Omega-agatoxins: novel calcium channel antagonists of two subtypes from funnel web spider (Agelenopsis aperta). J. Biol. Chem. 265:1990;861-867.
    • (1990) J. Biol. Chem. , vol.265 , pp. 861-867
    • Adams, M.E.1    Bindokas, V.P.2    Hasegawa, L.3    Venema, V.J.4
  • 5
    • 0024354054 scopus 로고
    • High resolution of honey bee (Apis mellifera) venom peptides by propionic acid/urea polyacrilamide gel electrophoresis after ethanol precipitation
    • Chettibi S., Lawrence A. High resolution of honey bee (Apis mellifera) venom peptides by propionic acid/urea polyacrilamide gel electrophoresis after ethanol precipitation. Toxicon. 27:1989;781-787.
    • (1989) Toxicon , vol.27 , pp. 781-787
    • Chettibi, S.1    Lawrence, A.2
  • 6
    • 0026705696 scopus 로고
    • The purification and amino acid sequences of four Tx2 neurotoxins from the venom of the Brazilian armed spider Phoneutria nigriventer (Keys.)
    • Cordeiro M.N., Diniz C.R., Valentim A.C., Von Eickstedt V.R.D., Gilroy J., Richardson M. The purification and amino acid sequences of four Tx2 neurotoxins from the venom of the Brazilian armed spider Phoneutria nigriventer (Keys.). FEBS Lett. 310:(2):1992;153-156.
    • (1992) FEBS Lett. , vol.310 , Issue.2 , pp. 153-156
    • Cordeiro, M.N.1    Diniz, C.R.2    Valentim, A.C.3    Von Eickstedt, V.R.D.4    Gilroy, J.5    Richardson, M.6
  • 7
    • 0027465984 scopus 로고
    • Purification and amino acid sequences of six Tx3 type neurotoxins from the venom of Brazilian armed spider Phoneutria nigriventer (Keys.)
    • Cordeiro M.N., Figueiredo S.G., Valentim A.C., Diniz C.R., Von Eickstedt R.D., Gilroy J., Richardson M. Purification and amino acid sequences of six Tx3 type neurotoxins from the venom of Brazilian armed spider Phoneutria nigriventer (Keys.). Toxicon. 31:1993;35-42.
    • (1993) Toxicon , vol.31 , pp. 35-42
    • Cordeiro, M.N.1    Figueiredo, S.G.2    Valentim, A.C.3    Diniz, C.R.4    Von Eickstedt, R.D.5    Gilroy, J.6    Richardson, M.7
  • 8
    • 0023202784 scopus 로고
    • Reexamination of the specificity of the scorpion Androctonus australis Hector insect toxin towards arthropods
    • De Dianous S., Hoarau F., Rochat H. Reexamination of the specificity of the scorpion Androctonus australis Hector insect toxin towards arthropods. Toxicon. 25:1987;411-417.
    • (1987) Toxicon , vol.25 , pp. 411-417
    • De Dianous, S.1    Hoarau, F.2    Rochat, H.3
  • 10
    • 0025349850 scopus 로고
    • The purification and amino acid sequence of the lethal neurotoxin Tx1 from the venom of the Brazilian 'armed' spider Phoneutria nigriventer
    • Diniz C.R., Cordeiro M.N., Rezende L. Jr., Kelly P., Fischer S., Reimann F., Oliveira E.B., Richardson M. The purification and amino acid sequence of the lethal neurotoxin Tx1 from the venom of the Brazilian 'armed' spider Phoneutria nigriventer. FEBS Lett. 263:(2):1990;251-253.
    • (1990) FEBS Lett. , vol.263 , Issue.2 , pp. 251-253
    • Diniz, C.R.1    Cordeiro, M.N.2    Rezende Jr., L.3    Kelly, P.4    Fischer, S.5    Reimann, F.6    Oliveira, E.B.7    Richardson, M.8
  • 11
    • 0033731951 scopus 로고    scopus 로고
    • Structure and pharmacology of spider venom neurotoxins
    • Escoubas P., Diochot S., Corzo G. Structure and pharmacology of spider venom neurotoxins. Biochimie. 82:2000;893-907.
    • (2000) Biochimie , vol.82 , pp. 893-907
    • Escoubas, P.1    Diochot, S.2    Corzo, G.3
  • 12
    • 0028920782 scopus 로고
    • Purification and amino acid sequence of the insecticidal neurotoxin Tx4(6-1) from the venom of the 'armed' spider Phoneutria nigriventer (Keys.)
    • Figueiredo S.G., De Lima M.E., Valentim A.C., Cordeiro M.N., Diniz C.R., Richardson M. Purification and amino acid sequence of the insecticidal neurotoxin Tx4(6-1) from the venom of the 'armed' spider Phoneutria nigriventer (Keys.). Toxicon. 33:(1):1995;83-93.
    • (1995) Toxicon , vol.33 , Issue.1 , pp. 83-93
    • Figueiredo, S.G.1    De Lima, M.E.2    Valentim, A.C.3    Cordeiro, M.N.4    Diniz, C.R.5    Richardson, M.6
  • 13
    • 0002739571 scopus 로고    scopus 로고
    • Purification and pharmacological activity of two potent insecticidal neurotoxins from Phoneutria nigriventer spider venom
    • Figueiredo S.G., Mafra R.A., Pimenta A.M.C., Cordeiro M.N., Diniz C.R., De Lima M.E. Purification and pharmacological activity of two potent insecticidal neurotoxins from Phoneutria nigriventer spider venom. J. Venom. Anim. Toxins. 3:(1):1997;231.
    • (1997) J. Venom. Anim. Toxins , vol.3 , Issue.1 , pp. 231
    • Figueiredo, S.G.1    Mafra, R.A.2    Pimenta, A.M.C.3    Cordeiro, M.N.4    Diniz, C.R.5    De Lima, M.E.6
  • 14
    • 0034598649 scopus 로고    scopus 로고
    • Purification and amino acid sequence of a highly insecticidal toxin from the venom of the Brazilian spider Phoneutria nigriventer which inhibits NMDA-evoked currents in rat hippocampal neurones
    • Figueiredo S.G., De Lima M.E., Cordeiro M.N., Diniz C.R., Patten D., Halliwell R.F., Gilroy J., Richardson M. Purification and amino acid sequence of a highly insecticidal toxin from the venom of the Brazilian spider Phoneutria nigriventer which inhibits NMDA-evoked currents in rat hippocampal neurones. Toxicon. 39:2001;309-317.
    • (2001) Toxicon , vol.39 , pp. 309-317
    • Figueiredo, S.G.1    De Lima, M.E.2    Cordeiro, M.N.3    Diniz, C.R.4    Patten, D.5    Halliwell, R.F.6    Gilroy, J.7    Richardson, M.8
  • 15
    • 0021330769 scopus 로고
    • Glutamate: A neurotransmitter in mammalian brain
    • Fonnum F. Glutamate: a neurotransmitter in mammalian brain. J. Neurochem. 42:1984;1-11.
    • (1984) J. Neurochem. , vol.42 , pp. 1-11
    • Fonnum, F.1
  • 16
    • 0014939933 scopus 로고
    • The chromatographic determination of cystine and cysteine residues in proteins as s-beta-(4-pyridylethyl)cysteine
    • Friedman M., Krull L.H., Cavins J.F. The chromatographic determination of cystine and cysteine residues in proteins as s-beta-(4-pyridylethyl)cysteine. J. Biol. Chem. 245:(15):1970;3868-3871.
    • (1970) J. Biol. Chem. , vol.245 , Issue.15 , pp. 3868-3871
    • Friedman, M.1    Krull, L.H.2    Cavins, J.F.3
  • 17
    • 73049155988 scopus 로고
    • The isolation of nerve endings from brain: An electron microscope study of cell fragments derived by homogenization and centrifugation
    • Gray E.G., Whittaker V.P. The isolation of nerve endings from brain: an electron microscope study of cell fragments derived by homogenization and centrifugation. J. Anat. 96:1962;79-87.
    • (1962) J. Anat. , vol.96 , pp. 79-87
    • Gray, E.G.1    Whittaker, V.P.2
  • 19
    • 0019940275 scopus 로고
    • Spider venom contains specific receptor blocker of glutaminergic synapses
    • Kawai N., Niwa A., Abe T. Spider venom contains specific receptor blocker of glutaminergic synapses. Brain Res. 247:(1):1982;169-171.
    • (1982) Brain Res. , vol.247 , Issue.1 , pp. 169-171
    • Kawai, N.1    Niwa, A.2    Abe, T.3
  • 21
    • 0001914208 scopus 로고
    • Isolierung and Krystallisation eines Garugferments aus Tumoren
    • Kubowitz F., Ott C. Isolierung and Krystallisation eines Garugferments aus Tumoren. Biochem. Z. 319:1943;94-117.
    • (1943) Biochem. Z. , vol.319 , pp. 94-117
    • Kubowitz, F.1    Ott, C.2
  • 23
    • 0034768977 scopus 로고    scopus 로고
    • Pharmacology and biochemistry of spider venoms
    • Rash L.D., Hodgson W.C. Pharmacology and biochemistry of spider venoms. Toxicon. 40:2002;225-254.
    • (2002) Toxicon , vol.40 , pp. 225-254
    • Rash, L.D.1    Hodgson, W.C.2
  • 25
    • 0033549272 scopus 로고    scopus 로고
    • PhTx4, a new class of toxins from Phoneutria nigriventer spider venom, inhibits the glutamate uptake in rat brain synaptosomes
    • Mafra R.A., Figueiredo S.G., Diniz C.R., Cordeiro M.N., Cruz J.S., De Lima M.E. PhTx4, a new class of toxins from Phoneutria nigriventer spider venom, inhibits the glutamate uptake in rat brain synaptosomes. Brain Res. 831:1999;297-300.
    • (1999) Brain Res. , vol.831 , pp. 297-300
    • Mafra, R.A.1    Figueiredo, S.G.2    Diniz, C.R.3    Cordeiro, M.N.4    Cruz, J.S.5    De Lima, M.E.6
  • 27
    • 0030954604 scopus 로고    scopus 로고
    • Application of physiologically active substances isolated from natural resources to pharmacological studies
    • Ohizumi Y. Application of physiologically active substances isolated from natural resources to pharmacological studies. Jpn. J. Pharmacol. 73:(4):1997;263-289.
    • (1997) Jpn. J. Pharmacol. , vol.73 , Issue.4 , pp. 263-289
    • Ohizumi, Y.1
  • 28
    • 0029876591 scopus 로고    scopus 로고
    • Insect neurotransmission: Neurotransmitters and their receptors
    • Osborne R.H. Insect neurotransmission: neurotransmitters and their receptors. Pharmacol. Ther. 69:1996;117-142.
    • (1996) Pharmacol. Ther. , vol.69 , pp. 117-142
    • Osborne, R.H.1
  • 30
    • 0034856719 scopus 로고    scopus 로고
    • Moving pieces in a proteomic puzzle: Mass fingerprinting of toxic fractions from the venom of Tityus serrulatus (Scorpiones, Buthidae)
    • Pimenta A.M.C., Stocklin R., Favreau P., Bougis P.E., Martin-Eauclaire M.F. Moving pieces in a proteomic puzzle: mass fingerprinting of toxic fractions from the venom of Tityus serrulatus (Scorpiones, Buthidae). Rapid Commun. Mass Spectrom. 15:(17):2001;1562-1572.
    • (2001) Rapid Commun. Mass Spectrom. , vol.15 , Issue.17 , pp. 1562-1572
    • Pimenta, A.M.C.1    Stocklin, R.2    Favreau, P.3    Bougis, P.E.4    Martin-Eauclaire, M.F.5
  • 31
    • 0035401349 scopus 로고    scopus 로고
    • Purification, amino-acid sequence and partial characterization of two toxins with anti-insect activity from the venom of the South American scorpion Tityus bahiensis (Buthidae)
    • Pimenta A.M.C., Martin-Eauclaire M.F., Rochat H., Figueiredo S.G., Kalapothakis E., Afonso L.C., De Lima M.E. Purification, amino-acid sequence and partial characterization of two toxins with anti-insect activity from the venom of the South American scorpion Tityus bahiensis (Buthidae). Toxicon. 39:(7):2001;1009-1019.
    • (2001) Toxicon , vol.39 , Issue.7 , pp. 1009-1019
    • Pimenta, A.M.C.1    Martin-Eauclaire, M.F.2    Rochat, H.3    Figueiredo, S.G.4    Kalapothakis, E.5    Afonso, L.C.6    De Lima, M.E.7
  • 32
    • 0001551016 scopus 로고
    • Purification and chemical characterization of the major toxins from the venom of the Brazilian scorpion Tityus serrulatus (Lutz and Mello)
    • Possani L.D., Martin B.M., Mochea-Morales J., Svendsen L. Purification and chemical characterization of the major toxins from the venom of the Brazilian scorpion Tityus serrulatus (Lutz and Mello). Carlsberg Res. Commun. 46:1981;195-205.
    • (1981) Carlsberg Res. Commun. , vol.46 , pp. 195-205
    • Possani, L.D.1    Martin, B.M.2    Mochea-Morales, J.3    Svendsen, L.4
  • 33
    • 0030020792 scopus 로고    scopus 로고
    • A novel tool for the investigation of glutamate release from rat cerebrocortical synaptosomes: The toxin Tx3-3 from the venom of the spider Phoneutria nigriventer
    • Prado M.A.M., Guatimosim C., Gomez M.V., Diniz C.R., Cordeiro M.N., Romano-Silva M.A. A novel tool for the investigation of glutamate release from rat cerebrocortical synaptosomes: the toxin Tx3-3 from the venom of the spider Phoneutria nigriventer. Biochem. J. 314:1996;145-150.
    • (1996) Biochem. J. , vol.314 , pp. 145-150
    • Prado, M.A.M.1    Guatimosim, C.2    Gomez, M.V.3    Diniz, C.R.4    Cordeiro, M.N.5    Romano-Silva, M.A.6
  • 34
    • 0026049291 scopus 로고
    • Isolation of neurotoxic peptides from the venom of the 'armed' spider Phoneutria nigriventer
    • Rezende L. Jr., Cordeiro M.N., Oliveira E.B., Diniz C.R. Isolation of neurotoxic peptides from the venom of the 'armed' spider Phoneutria nigriventer. Toxicon. 29:(10):1991;1225-1233.
    • (1991) Toxicon , vol.29 , Issue.10 , pp. 1225-1233
    • Rezende Jr., L.1    Cordeiro, M.N.2    Oliveira, E.B.3    Diniz, C.R.4
  • 35
    • 0020640298 scopus 로고
    • Isolation and characterization of toxic proteins from the venom of the Brazilian scorpion Tityus serrulatus
    • Sampaio S.V., Laure C.J., Giglio J.R. Isolation and characterization of toxic proteins from the venom of the Brazilian scorpion Tityus serrulatus. Toxicon. 21:1982;265-277.
    • (1982) Toxicon , vol.21 , pp. 265-277
    • Sampaio, S.V.1    Laure, C.J.2    Giglio, J.R.3
  • 36
    • 0033400679 scopus 로고    scopus 로고
    • Binding sites and actions of Tx1, a neurotoxin from the venom of the spider Phoneutria nigriventer, in guinea pig ileum
    • Santos R.G., Diniz C.R., Cordeiro M.N., De Lima M.E. Binding sites and actions of Tx1, a neurotoxin from the venom of the spider Phoneutria nigriventer, in guinea pig ileum. Braz. J. Med. Biol. Res. 32:1999;1565-1569.
    • (1999) Braz. J. Med. Biol. Res. , vol.32 , pp. 1565-1569
    • Santos, R.G.1    Diniz, C.R.2    Cordeiro, M.N.3    De Lima, M.E.4
  • 37
    • 0019397589 scopus 로고
    • Glutamate synapses and receptors on insect muscle
    • Usherwood P.N. Glutamate synapses and receptors on insect muscle. Adv. Biochem. Psychopharmacol. 27:1981;183-193.
    • (1981) Adv. Biochem. Psychopharmacol. , vol.27 , pp. 183-193
    • Usherwood, P.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.