Acanthosis nigricans is a reliable cutaneous marker of insulin resistance in obese Japanese children

Pediatrics International

Volumn 45, Issue 6, 2003, Pages 701-705

  Yamazaki, Hajime ^a,b   Ito, Sueshi ^a   Yoshida, Hiroshi ^a  

^a Tsuruoka City Shonai Hospital   (Japan)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

Acanthosis nigricans; Insulin resistance; Normal glucose tolerance; Oral glucose tolerance test; Type 2 diabetes

Indexed keywords

BIOCHEMICAL MARKER; GLUCOSE; LIPID;

ACANTHOSIS NIGRICANS; ADOLESCENT; ARTICLE; BIRTH WEIGHT; BLOOD PRESSURE; BODY HEIGHT; BODY WEIGHT; CHILD; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; JAPAN; LIPID BLOOD LEVEL; LIVER FUNCTION; MAJOR CLINICAL STUDY; MALE; NECK; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PATIENT SELECTION; PRIORITY JOURNAL; TOXICITY;

ACANTHOSIS NIGRICANS; CHILD; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN RESISTANCE; JAPAN; MALE; OBESITY;

EID: 1642439999     PISSN: 13288067     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1442-200X.2003.01812.x     Document Type: Article

References (10)

1. Ebling FJG, Rook A. Acanthosis nigricans. In: Rook A, Wilkinson DS, Ebling FJG (eds). Textbook of Dermatology. Blackwell Scientific Publications, Oxford, 1979, 1307-10.
2. Flier JS, Eastman RC, Minaker KL, Mattesen D, Rowe JW. Acanthosis nigricans in obese women with hyperandrogenism. Characterization of an insulin-resistant state distinct from the type A and B syndromes. Diabetes 1985; 34: 101-7.
3. Dunaif A, Graf M, Mandeli J, Laumas V, Dobrjansky A. Characterization of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance, and/or hyperinsulinemia. J. Clin. Endocrinol. Metab 1987; 65: 499-507.
4. Dunaif A, Green G, Phelps RG, Lebwohl M, Futterweit W, Lewy L. Acanthosis nigricans, insulin action, and hyperandrogenism: clinical, histological, and biochemical findings. J. Clin. Endocrinol. Metab 1991; 73: 590-95.
5. Stuart CA, Pate CJ, Peters EJ. Prevalence of acanthosis nigricans in an unselected population. Am. J. Med. 1989; 87: 269-72.
6. Kuzuya T, Nakagawa S, Satoh J et al. Report of the committee of Japan Diabetes Society on the classification and diagnostic criteria of diabetes mellitus. J. Japan Diab. Soc. 1999; 42: 385-404.
7. Murata M, Yamazaki K, Itani A, Inaba M. Standard body weight for age between 5 years and 17 years. Shouni Hoken Kenkyu 1980; 39: 93-6.
8. Fagot-Campagna A, Pettitt DJ, Engelgau MM et al. Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective. J. Pediatr. 2000; 136: 664-72.
9. Stuart CA, Gilkison CR, Smith MM, Bosma AM, Keenan BS, Nagamani M. Acanthosis nigricans as a risk factor for non-insulin dependent diabetes mellitus. Clin. Pediatr. (Phila) 1998; 37: 73-9.
10. Mukhtar Q, Cleverley G, Voorhees RE, McGrath JW. Prevalence of acanthosis nigricans and its association with hyperinsulinemia in New Mexico adolescents. J. Adolesc. Health 2001; 28: 372-6.