Transgene stability for three replication-competent murine leukemia virus vectors

Gene

Volumn 329, Issue 1-2, 2004, Pages 61-69

  Duch, Mogens ^a   Carrasco, Maria L ^a   Jespersen, Thomas ^a,b   Hansen, Bettina D ^a   Pedersen, Finn Skou ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Complete revertants; Deletion mutants; DMEM; Enhanced green fluorescence protein; Gene transfer; Internal ribosome entry site; International ribosome entry site; IRES; Long terminal repeats; LTR; MLV; Murine leukemia virus; Retroviral vector

Indexed keywords

GREEN FLUORESCENT PROTEIN; RETROVIRUS VECTOR;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; DNA FLANKING REGION; GENE CASSETTE; GENE INSERTION; GENE REPLICATION; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; MOUSE; MURINE LEUKEMIA VIRUS VECTOR; NONHUMAN; PRIORITY JOURNAL; RNA TRANSLATION; TRANSGENE; VIRUS GENOME;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CELL LINE; DNA, RECOMBINANT; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; LEUKEMIA VIRUS, MURINE; LUMINESCENT PROTEINS; MICE; MOLECULAR SEQUENCE DATA; TRANSFECTION; TRANSGENES; VIRUS REPLICATION;

MURINAE; MURINE LEUKEMIA VIRUS;

EID: 1642386937     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2003.12.032     Document Type: Article

References (28)

1. An W., Telesnitsky A. Frequency of direct repeat deletion in a human immunodeficiency virus type 1 vector during reverse transcription in human cells. Virology. 286:2001;475-482.
2. An W., Telesnitsky A. Effects of varying sequence similarity on the frequency of repeat deletion during reverse transcription of a human immunodeficiency virus type 1 vector. J. Virol. 76:2002;7897-7902.
3. Bacharach E., Gonsky J., Lim D., Goff S.P. Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5′ plus-strand DNA ends in vivo. J. Virol. 74:2000;4755-4764.
4. Bachrach E., Pelegrin M., Piechaczyk M., Pedersen F.S., Duch M. Efficient gene transfer into spleen cells of newborn mice by a replication-competent retroviral vector. Virology. 293:2002;328-334.
5. Bachrach E., Duch M., Pelegrin M., Dreja H., Pedersen F.S., Piechaczyk M. In vivo infection of mice by replication-competent MLV-based retroviral vectors. Methods Mol. Med. 76:2003;343-352.
6. Carrasco, M.L., Duch, M., Pedersen, F.S., 2004. Patch insertion of tRNA sequences at sites of heterologous sequence deletions in a replication competent retroviral vector. Submitted for publication.
7. Chang Z., Pan J., Logg C., Kasahara N., Roy-Burman P. A replication-competent feline leukemia virus, subgroup A (FeLV-A), tagged with green fluorescent protein reporter exhibits in vitro biological properties similar to those of the parental FeLV-A. J. Virol. 75:2001;8837-8841.
8. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
9. Duch, M., Carrasco, M.L., Jespersen, T., Aagaard, L., Pedersen, F.S., 2004. An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo. Submitted for publication.
10. Etzerodt M., Mikkelsen T., Pedersen F.S., Kjeldgaard N.O., Jorgensen P. The nucleotide sequence of the Akv murine leukemia virus genome. Virology. 134:1984;196-207.
11. Feinberg A.P., Vogelstein B. Alterations in DNA methylation in human colon neoplasia. Sem. Surg. Oncol. 3:1987;149-151.
12. Gelinas C., Temin H.M. Nondefective spleen necrosis virus-derived vectors define the upper size limit for packaging reticuloendotheliosis viruses. Proc. Natl. Acad. Sci. 83:1986;9211-9215.
13. Graham F.L., van der Eb A.J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 52:1973;456-467.
14. Jang S.K., Krausslich H.G., Nicklin M.J., Duke G.M., Palmenberg A.C., Wimmer E. A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J. Virol. 62:1988;2636-2643.
15. Jespersen T., Duch M., Carrasco M.L., Warming S., Pedersen F.S. Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors. Gene. 239:1999;227-235.
16. Jorgensen P., Mikkelsen T., Pedersen F.S., Kjeldgaard N.O. An MuLV transmission vector system designed to permit recovery in E. coli of proviral and cellular flanking sequences. Virus Genes. 1:1988;221-233.
17. Logg C.R., Logg A., Tai C.K., Cannon P.M., Kasahara N. Genomic stability of murine leukemia viruses containing insertions at the Env-3′ untranslated region boundary. J. Virol. 75:2001;6989-6998.
18. Logg C.R., Tai C.K., Logg A., Anderson W.F., Kasahara N. A uniquely stable replication-competent retrovirus vector achieves efficient gene delivery in vitro and in solid tumors. Hum. Gene Ther. 12:2001;921-932.
19. Pear W.S., Nolan G.P., Scott M.L., Baltimore D. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. U. S. A. 90:1993;8392-8396.
20. Pedersen F.S., Duch M. Replication competent retroviral vectors. Bioforum Int. 6:2002;100-104.
21. Pfeiffer J.K., Telesnitsky A. Effects of limiting homology at the site of intermolecular recombinogenic template switching during Moloney murine leukemia virus replication. J. Virol. 75:2001;11263-11274.
22. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd ed. 1989;Cold Spring Harbour Press, NY.
23. Shin N.H., Hartigan-O'Connor D., Pfeiffer J.K., Telesnitsky A. Replication of lengthened Moloney murine leukemia virus genomes is impaired at multiple stages. J. Virol. 74:2000;2694-2702.
24. Solly S.K., Trajcevski S., Frisen C., Holzer G.W., Nelson E., Clerc B., Abordo-Adesida E., Castro M., Lowenstein P., Klatzmann D. Replicative retroviral vectors for cancer gene therapy. Cancer Gene Ther. 10:2003;30-39.
25. Van Beveren C., Coffin J., Hughes S. Nucleotide sequences complemented with functional and structural analysis. Weiss R., Teich H., Varmus H., Coffin J. RNA Tumor Viruses. 1985;790-805 CSHL Press, New York.
26. Yin P.D., Hu W.S. Insertion of sequences into the 3′ untranslated region of a replication-competent spleen necrosis virus vector disrupts env gene expression. Arch. Virol. 144:1999;73-87.
27. Yu S.S., Kim J.M., Kim S. The 17 nucleotides downstream from the env gene stop codon are important for murine leukemia virus packaging. J. Virol. 74:2000;8775-8780.
28. Zhao S.C., Li M.X., Banerjee D., Schweitzer B.I., Mineishi S., Gilboa E., Bertino J.R. Long-term protection of recipient mice from lethal doses of methotrexate by marrow infected with a double-copy vector retrovirus containing a mutant dihydrofolate reductase. Cancer Gene Ther. 1:1994;27-33.