A Rapid Quantitative Turbimetric D-dimer Assay Has High Sensitivity for Detection of Pulmonary Embolism in the ED

American Journal of Emergency Medicine

Volumn 22, Issue 2, 2004, Pages 111-114

  Kulstad, Erik B ^a,b   Kulstad, Christine E ^a   Lovell, Elise O ^a  

^a ADVOCATE CHRIST MEDICAL CENTER   (United States)

^b NONE   (United States)

Author keywords

D dimer; Diagnosis; Emergency department; Pulmonary embolism

Indexed keywords

D DIMER;

ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; EMERGENCY WARD; HUMAN; LUNG EMBOLISM; LUNG VENTILATION PERFUSION RATIO; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RETROSPECTIVE STUDY; TURBIDIMETRY;

EID: 1642380565     PISSN: 07356757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajem.2003.12.002     Document Type: Article

References (27)

1. Duet M, Benelhadj S, Kedra W, et al: A new quantitative d-dimer assay appropriate in emergency: reliability of the assay for pulmonary embolism exclusion diagnosis. Thromb Res 1998;91:1-5
2. Meyer G, Fischer AM, Collignon MA, et al: Diagnostic value of two rapid and individual d-dimer assays in patients with clinically suspected pulmonary embolism: comparison with microplate enzyme-linked immunosorbent assay. Blood Coagul Fibrinolysis 1998; 9:603-608
3. Oger E, Leroyer C, Bressollette L, et al: Evaluation of a new, rapid, and quantitative d-dimer test in patients with suspected pulmonary embolism. Am J Respir Crit Care Med 1998;158:65-70
4. Reber G, Bounameaux H, Perrier A, de Moerloose P: Performances of a new, rapid and automated microlatex d-dimer assay for the exclusion of pulmonary embolism in symptomatic outpatients. Thromb Haemost 1998;80:719-720
5. Dunn KL, Wolf JP, Dorfman DM, Fitzpatrick P, Baker JL, Goldhaber SZ: Normal d-dimer levels in emergency department patients suspected of acute pulmonary embolism. J Am Coll Cardiol 2002; 40:1475-1478
6. Kline JA, Johns KL, Colucciello SA, et al: New diagnostic tests for pulmonary embolism. Ann Emerg Med 2000;35:168-180
7. Kline JA, Nelson RD, Jackson RE, Courtney DM: Criteria for the safe use of d-dimer testing in emergency department patients with suspected pulmonary embolism: a multicenter US study. Ann Emerg Med 2002;39:144-152
8. Escoffre-Barbe M, Oger E, Leroyer C, et al: Evaluation of a new rapid d-dimer assay for clinically suspected deep venous thrombosis (Liatest D-dimer). Am J Clin Pathol 1998;109:748-753
9. Roussi J, Bentolila S, Boudaoud L, et al: Contribution of d-dimer determination in the exclusion of deep venous thrombosis in spinal cord injury patients. Spinal Cord 1999;37:548-552
10. Harper P, Marson C, Grimmer A, Monahan K, Humm G, Baker B: The rapid whole blood agglutination d-dimer assay has poor sensitivity for use as an exclusion test in suspected deep vein thrombosis. N Z Med J 2001;114:61-64
11. Funfsinn N, Caliezi C, Biasiutti FD, et al: Rapid d-dimer testing and pre-test clinical probability in the exclusion of deep venous thrombosis in symptomatic outpatients. Blood Coagul Fibrinolysis 2001;12:165-170
12. Anderson DR, Wells PS: D-dimer for the diagnosis of venous thromboembolism. Curr Opin Hematol 2000;7:296-301
13. Adcock D, Joiner-Maier D: An automated, rapid ELISA for the determination of d-dimer in the evaluation of venous thrombosis. Am Clin Lab 1999;18:6
14. Farrell S, Hayes T, Shaw M: A negative SimpliRED d-dimer assay result does not exclude the diagnosis of deep vein thrombosis or pulmonary embolus in emergency department patients. Ann Emerg Med 2000;35:121-125
15. Kutinsky I, Blakley S, Roche V: Normal d-dimer levels in patients with pulmonary embolism. Arch Intern Med 1999;159:1569-1572
16. Pappas AA, Dalrymple G, Harrison K, et al: The application of a rapid d-dimer test in suspected pulmonary embolus. Arch Pathol Lab Med 1993;117:977-980
17. Quinn DA, Fogel RB, Smith CD, et al: D-dimers in the diagnosis of pulmonary embolism. Am J Respir Crit Care Med 1999; 159:1445-1449
18. Harrison KA, Haire WD, Pappas AA, et al: Plasma d-dimer: a useful tool for evaluating suspected pulmonary embolus. J Nucl Med 1993;34:896-898
19. van der Graaf F, van den Borne H, van der Kolk M, de Wild PJ, Janssen GW, van Uum SH: Exclusion of deep venous thrombosis with d-dimer testing-comparison of 13 d-dimer methods in 99 outpatients suspected of deep venous thrombosis using venography as reference standard. Thromb Haemost 2000;83:191-198
20. Dempfle C, Schraml M, Besenthal I, et al: Multicentre evaluation of a new point-of-care test for the quantitative determination of d-dimer. Clin Chim Acta 2001;307:211-218
21. Houbouyan-Reveillard LL, Mihoubi A, Houdijk WP, et al: Preliminary evaluation of two new rapid immunoturbidimetric d-dimer assays in patients with clinically suspected venous thromboembolism (VTE). Thromb Haemost 2000;84:770-774
22. Gilbert EH, Lowenstein SR, Koziol-McLain J, Barta DC, Steiner J: Chart reviews in emergency medicine research: where are the methods? Ann Emerg Med 1996;27:305-308
23. GraphPad. Available at: http://graphpad.com. 2002 Accessed February 20, 2003
24. Prologo JD, Glauser J: Variable diagnostic approach to suspected pulmonary embolism in the ED of a major academic tertiary care center. Am J Emerg Med 2002;20:5-9
25. Wells PS, Anderson DR, Rodger M, et al: Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and d-dimer. Ann Intern Med 2001;135:98-107
26. Fesmire FM, Kline JA, Wolf SJ: Clinical policy: critical issues in the evaluation and management of adult patients presenting with suspected pulmonary embolism. Ann Emerg Med 2003;41:257-270
27. Prosser RL Jr: De disappearing d-dimer. Ann Emerg Med 2003;41:154-155; author reply 155