Prothrombin gene variant (G20210A) in a patient with cerebral venous sinus thrombosis and bilateral deep vein thrombosis [1];Mutación del gen de la protrombina (G20210A) en un paciente con trombosis de senos venosos cerebrales y trombosis venosa profunda bilateral

Medicina Clinica

Volumn 122, Issue 4, 2004, Pages 158-

  Ortin, Xavier ^a   Ugarriza, Aránzazu ^a   Escoda, Lourdes ^a   Mesa, Rafel ^a  

^a HOSPITAL UNIVERSITARI JOAN XXIII   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN III; BLOOD CLOTTING FACTOR 5 LEIDEN; PHOSPHOLIPID ANTIBODY; PROTEIN C; PROTEIN S;

ADULT; ANTIPHOSPHOLIPID SYNDROME; ANTITHROMBIN III DEFICIENCY; BLOOD CLOTTING FACTOR 5 DEFICIENCY; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; GENE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; HEADACHE; HUMAN; HYPERCOAGULABILITY; LETTER; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MORTALITY; NAUSEA; NEUROLOGIC EXAMINATION; OCCLUSIVE CEREBROVASCULAR DISEASE; PROTEIN C DEFICIENCY; PROTEIN S DEFICIENCY; PROTHROMBIN GENE; RISK FACTOR; THROMBOEMBOLISM; THROMBOPHILIA; TREATMENT CONTRAINDICATION; VEIN THROMBOSIS; VOMITING;

EID: 1642380291     PISSN: 00257753     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0025-7753(04)74178-0     Document Type: Letter

References (10)

1. Heckmann JG, Tomandl B, Erbguth F, Neidhardt B, Zingsem H, Neundörfer B. Cerebral vein thrombosis and prothrombin gene (G20210A) mutation. Clin Neurol Neurosurg 2001;103:191-3.
2. Stolz E, Kemkes-Matthes B, Pötzsch B, Hahn M, Kraus J, Wirbartz A, et al. Screening for thrombophilic risk factors among 25 German patients with cerebral venous thrombosis. Acta Neurol Scand 2000;103:31-6.
3. Martinelli I, Sacchi E, Gianluca L, Taioli E, Duca F, Mannucci PM. High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives. N Engl J Med 1998;33:1793-7.
4. 20210 → A transition is a risk factor for cerebral venous thrombosis. Stroke 1998;29:1765-9.
5. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996;88:3698-703.
6. Madonna P, De Stefano V, Coppola A, Albisinni R, Cerbone A. G20210A PRTH gene mutation and other trombophilic polymorphisms in patients with cerebral vein trombosis. Stroke 2000;31:1787-88.
7. Krimpen J, Leebeek F, Dippel D, Gómez García E. Prothrombin gene variant (G20210A) in a patient with cerebral venous sinus thrombosis. Clin Neurol Neurosurg 1999;101:53-5.
8. Biousse V, Conard J, Briuzes C, Horellou MH, Ameri A, Bousser MG. Frequency of the 20210 G → A mutation in the 3′-untranslated region of the prothrombin gene in 35 cases of cerebral venous thrombosis. Stroke 1998;29:1398-400.
9. 20210 → A transition is a risk factor for cerebral venous trombosis. Stroke 1998;29:1765-69.
10. Simons P, Vanhooren G. Cerebral venous thrombosis and the G20210A mutation of factor II. Stroke 2000;31:543.