99mTc-labeled murine ior C5 monoclonal antibody in colorectal carcinoma patients: Pharmacokinetics, biodistribution, absorbed radiation doses to normal organs and tissues and tumor localization

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 26, Issue 9, 2004, Pages 687-696

  Iznaga Escobar, N ^a   Ramos Suzarte, M ^a   Morales Morales, A ^a   Torres Arocha, L ^b   Rodriguez Mesa N ^b   Perez Rodriguez R ^a  

^a CENTER OF MOLECULAR IMMUNOLOGY   (Cuba)

^b Medical Surgical Research Center   (Cuba)

Author keywords

Biodistribution; Dosimetry; mAb ior C5; Radiolabeling; Tumor localization

Indexed keywords

HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; MEDRONATE TECHNETIUM TC 99M; MEDRONIC ACID; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY IOR C5; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BOLUS INJECTION; BONE SCINTISCANNING; CLINICAL ARTICLE; COLORECTAL CARCINOMA; COMPARTMENT MODEL; DOSIMETRY; DRUG CLEARANCE; DRUG HALF LIFE; FEMALE; HEART; HUMAN; IMMUNOREACTIVITY; ISOTOPE LABELING; KIDNEY; LIVER; MALE; RADIATION DOSE; SCINTILLATION CAMERA; SIDE EFFECT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPLEEN; TISSUE DISTRIBUTION; TUMOR LOCALIZATION; URINARY EXCRETION; WHOLE BODY SCINTISCANNING;

AGED; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; COLORECTAL NEOPLASMS; COMPLEMENT C5; CUBA; FEASIBILITY STUDIES; FEMALE; HALF-LIFE; HUMAN BODY; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MICE; MIDDLE AGED; RADIOPHARMACEUTICALS; RADIOTHERAPY DOSAGE; TECHNETIUM; TISSUE DISTRIBUTION;

EID: 1642371976     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2004.26.9.872566     Document Type: Article

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