Both catabolic pathways of histamine via histamine-N-melhyl-transferase and diamine oxidase are diminished in the colonic mucosa of patients with food allergy

Inflammation Research

Volumn 53, Issue SUPPL. 1, 2004, Pages

  Kuefner, M A ^a   Schwelberger, H G ^b   Weidenhiller, M ^c   Hahn, E G ^c   Raithel, M ^c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b Universitatsklinik fur Chirurgie Innsbruck   (Austria)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRALDEHYDE; AMINE OXIDASE (COPPER CONTAINING); HISTAMINE; HISTAMINE METHYLTRANSFERASE; IMMUNOGLOBULIN E; N METHYLHISTAMINE; PUTRESCINE; PYRROLINE DERIVATIVE;

ADULT; CATABOLISM; COLON MUCOSA; COLONOSCOPY; CONFERENCE PAPER; CONTROLLED STUDY; DEAMINATION; DIARRHEA; ENZYME ACTIVITY; FOOD ALLERGY; HISTAMINE METABOLISM; HUMAN; HUMAN TISSUE; METHYLATION; PROVOCATION TEST; SKIN MANIFESTATION;

ADULT; AMINE OXIDASE (COPPER-CONTAINING); COLON; FOOD HYPERSENSITIVITY; HISTAMINE N-METHYLTRANSFERASE; HISTAMINE RELEASE; HUMANS; INTESTINAL MUCOSA; MIDDLE AGED;

EID: 1642356756     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00011-003-0314-5     Document Type: Conference Paper

References (8)

1. Maslinski C, Fogel WA. Catabolism of histamine. In: Uvnäs B, editor, Handbook of experimental pharmacology. Vol. 97. Histamine and histamine antagonists. Berlin, Heidelberg: Springer 1991; 165-89.
2. Raithel M, Küfner M, Ulrich P, Hahn EG. The involvement of the histamine degradation pathway by diamine oxidase in manifest gastrointestinal allergies. Inflamm Res 1999; 48 Suppl 1: S75-6.
3. Kuefner M, Schwelberger HG, Ulrich P, Hahn EG, Raithel M. Total histamine degradation capacity (THDC) as an important biological marker of histamine metabolism in human colonic mucosa. Inflamm Res 2002; 51 Suppl 1: S87-8.
4. Schwelberger HG, Klocker J, Sattler J, Bodner E. Determination of the activity of diamine oxidase in extremely small tissue samples. Inflamm Res 1995; 44 Suppl 1: S94-5.
5. Küfher MA, Ulrich P, Raithel M, Schwelberger HG. Determination of the histamine degradation capacity in extremely small human colon samples. Inflamm Res 2001; 50 Suppl 2: S96-7.
6. Crowe SE, Perdue MH. Gastrointestinal food hypersensitivity: basic mechanisms of pathophysiology. Gastroenterology 1992; 103: 1075-95.
7. Wantke F, Jarisch J, Götz M. Histamine-free diet: treatment of choice for histamine-induced food intolerance and supporting treatment for chronic headaches. Clin Exp Allergy 1993; 23: 982-5.
8. Bodmer S, Imark C, Kneubühl M. Biogenic amines in food: Histamine and food processing. Inflamm Res 1999; 48: 296-300.