Protein-Loaded Bioresorbable Fibers and Expandable Stents: Mechanical Properties and Protein Release

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 69, Issue 1, 2004, Pages 1-10

  Zilberman, Meital ^a   Schwade, Nathan D ^b   Eberhart, Robert C ^b,c  

^a TEL AVIV UNIVERSITY   (Israel)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS AT ARLINGTON   (United States)

Author keywords

Albumin release; Bioresorbable fibers; Mechanical properties; Poly(L lactic acid); Stent

Indexed keywords

MECHANICAL PROPERTIES; MOLECULAR WEIGHT; POLYMERS; PROTEINS; TISSUE;

EROSION RATE; MICROSPHERES;

BIOMEDICAL ENGINEERING;

ALBUMIN; MICROSPHERE; POLYLACTIC ACID; POLYMER; RESOMER L210;

ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; BIOMECHANICS; BIORESORBABLE STENT; BLOOD VESSEL; CHEMICAL STRUCTURE; COMPRESSIVE STRENGTH; CONTROLLED DRUG RELEASE; CORONARY STENT; DIFFUSION; EXPANDABLE STENT; FIBER; IN VITRO STUDY; MELTING POINT; MOLECULAR WEIGHT; PROTEIN SECRETION; STENT; STRESS STRAIN RELATIONSHIP; TENSILE STRENGTH; THERMAL ANALYSIS; TRACHEA STENT; URETHRA STENT; WOUND HEALING; YOUNG MODULUS;

EID: 1642354728     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.b.20026     Document Type: Article

References (22)

1. Eberhart RC, Su SH, Nguyen KT, Zilberman M, Tang L, Nelson KD, Frenkel P. Bioresorbable polymeric stents: Current status and future promise. J Biomater Sci Polym Ed (in press).
2. Leenslag JW, Pennings AJ, Bos RRM, Rosema FR, Boering G. Resorbable materials of poly(L-lactic acid). VI. Plates and screws for internal fracture fixation. Biomaterials 1987;8:70-73.
3. Bergsma EJ, Rozema FR, Bos RRM, de Bruijn WC. Foreign body reactions to resorbable poly(L-lactide) bone plates and screws used for the fixation of unstable zygomatic fractures. J Oral Maxillofac Surg 1993;51:666-670.
4. Bergsma EJ, de Bruijn WC, Rozema FR, Bos RRM, Boering G. Late degradation tissue response to poly(L-lactide) bone plates and screws. Biomaterials 1995;16:25-31.
5. Agrawal CM, Haas KF, Leopold DA, Clark H. Evaluation of poly(L-lactic acid) as a material for intravascular polymeric stents. Biomaterials 1992;13:176-182.
6. Pachence JM, Kohn J. Bioresorbable polymers for tissue engineering. In: Lanza RP, Langer R, Chick WL, editors. Principles of tissue engineering. San Diego: Academic Press, 1997. p 279.
7. Lewis DH. Controlled release of bioactive agents from lactide/ glycolide polymers. In: Chasin M, Langer R, editors. Biodegradable polymers as drug delivery systems. New York: Marcel Dekker; 1990. p. 1-41.
8. Leelarusamee N, Howard SA, Malango CJ, Ma JK. A method for the preparation of polylactic acid microencapsules of controlled particle size and drug loading. J Microencapsul 1988;5: 147-157.
9. Ye YW, Landau C, Willard JE, Rajasubramanian G, Moskowitz A, Aziz S, Meidell R, Eberhart RC. Bioresorbable microporous stents deliver recombinant adenovirus gene transfer vectors to the arterial wall. Ann Biomed Eng 1998;26:398-408.
10. Kemppainen E, Talja M, Riihela M, Pohjonen T, Tormala P, Alfthan O. A bioresorbable urethral stent. Urol Res 1993;21: 235-238.
11. Brauers A, Thissen O, Pfannschmidt O, Bienert H, Foerster A, Klee D, Michaeli W, Hocker H, Jakse. Development of a biodegradable uretenic stent: Surface modification and in vitro assessment. J Endourol 1997;11:399-403.
12. Agrawal CM, Clark HG. Deformation characteristics of a bioabsorbable intravascular stent. Invest Radiol 1992;27:1020-1024.
13. Gao R, Shi R, Qiao S, Song L, Li Y. A novel polymeric local heparin delivery stent: Initial experimental study. J Am Coll Cardiol 1996;27:85A.
14. Yamawaki T, Shimokawa H, Kozai T, Miyata K, Higo T, Tanaka E, Egashira K, Shiraishi T, Tamai H, Igaki K, Takeshita A. Intramural delivery of a specific tyrosine kinase inhibitor with biodegradable stent suppresses the restenotic changes of the coronary artery in pigs in vivo. J Am Coll Cardiol 1998;32: 780-786.
15. Tamai H, Igaki K, Kyo E, Kosuga K, Kawashima A, Matsui S, Komori H, Tsuji T, Motohara S, Uehata H. Initial and 6-month results of biodegradable poly-1-lactic acid coronary stents in humans. Circulation 2000;102:399-404.
16. Zilberman M, Eberhart RC, Schwade ND. In vitro study of drug loaded bioresorbable films and support structures. J Biomater Sci Polym Ed (in press).
17. Zilberman M, Schwade ND, Meidell RS, Eberhart RC. Structured drug loaded bioresorbable films for support structures. J Biomater Sci Polym Ed 2000;12:875-892.
18. Su S, Chao RY, Landau CL, Nelson KD, Timmons RB, Meidel RS, Eberhart RC. An expandable bioresorbable endovascular stent: 1. Fabrication and properties (in press).
19. Su S, Landau CL, Chao RYN, Timmons RB, Meidel RS, Tang L, Eberhart RC. Expandable, bioresorbable endovascular stent with anti-platelet and anti-inflammation treatments. Circulation 2001;104:507.
20. Celli MA, Scandola M. Thermal properties and physical aging of poly-1-lactic acid. Polymer 1992;33:2699-2710.
21. Morphology and order in crystalline polymers. In: Billmeyer FW, editor. Textbook of polymer science. New York: Wiley; 1984. p 141-184.
22. Peterlin A. The role of chain folding in fibers. Mark HF, Atlas SM, Cemia E, editors. Man-made fibers, science and technology. New York: Wiley Interscience; 1967. p 283-340.