Cutaneous Leishmaniasis: Recognition and Treatment

American Family Physician

Volumn 69, Issue 6, 2004, Pages 1455-1460

  Markle, William H ^a,b   Makhoul, Khaldoun ^a,c  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c Univ of Pittsburgh Med Ctr ^*

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; ANTIFUNGAL AGENT; ANTIMONY DERIVATIVE; MEGLUMINE ANTIMONATE; PAROMOMYCIN; PENTAMIDINE ISETHIONATE; STIBOGLUCONATE SODIUM;

ANEMIA; ARGENTINA; ARTHRALGIA; BONE MARROW TOXICITY; DIABETES MELLITUS; DIAGNOSTIC PROCEDURE; ECG ABNORMALITY; ENDEMIC DISEASE; FATIGUE; GASTROINTESTINAL SYMPTOM; HEALING; HIGH RISK PATIENT; HUMAN; IMMIGRANT; IMMUNOLOGICAL PROCEDURES; INCIDENCE; LEUKOPENIA; LIVER DYSFUNCTION; MIDDLE EAST; NEEDLE BIOPSY; NEPHROTOXICITY; NORTH AFRICA; PANCREAS INJURY; POLYMERASE CHAIN REACTION; PRURITUS; PSYCHODIDAE; PUNCH BIOPSY; REVIEW; SENSITIVITY AND SPECIFICITY; SIDE EFFECT; SKIN LEISHMANIASIS; SOLDIER; TRAVEL; TREATMENT INDICATION; UNITED STATES;

ANIMALS; ANTIPROTOZOAL AGENTS; DIAGNOSIS, DIFFERENTIAL; HUMANS; LEISHMANIA; LEISHMANIASIS, CUTANEOUS; PROTOZOAN VACCINES;

EID: 1642350982     PISSN: 0002838X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (21)

1. Dedet JP, Pratlong F. Leishmaniasis. In: Manson P, Cook GC, Zumla A, eds. Manson's Tropical diseases. 21st ed. London: Saunders, 2003:1339-64.
2. Herwaldt BL. Leishmaniasis. Lancet 1999;354:1191-9.
3. Cope SE, Schultz GW, Richards AL, Savage HM, Smith GC, Mitchell CJ, et al. Assessment of arthropod vectors of infectious diseases in areas of U.S. troop deployment in the Persian Gulf. Am J Trop Med Hyg 1996;54:49-53.
4. Hyams KC, Hanson K, Wignall FS. Escamilla J, Oldfield EC 3d. The impact of infectious diseases on the health of U.S. troops deployed to the Persian Gulf during operations Desert Shield and Desert Storm. Clin Infect Dis 1995;20:1497-504.
5. McNeil DG Jr. A region inflamed: medicine; hundreds of U.S. troops infected by parasite borne by sand flies, Army says. New York Times December 6, 2003:A,8.
6. Centers for Disease Control and Prevention (CDC). Cutaneous leishmaniasis in U.S. military personnel-Southwest/Central Asia, 2002-2003. MMWR Morb Mortal Wkly Rep 2003;52:1009-12.
7. Lane RP. Phlebotomine sandflies. In: Manson P, Cook GC, Zumla A, eds. Manson's Tropical diseases. 21st ed. London: Saunders, 2003:1733-41.
8. WHO fact sheet. The leishmaniases and leishmania/HIV coinfections. Accessed October 16, 2003, at: http://www.who.int/inf-fs/en/fact116.html.
9. Magill AJ. Leishmaniasis. In: Hunter GW, Strickland GT, eds. Hunter's Tropical medicine and emerging infectious diseases. 8th ed. Philadelphia: Saunders, 2000:665-87.
10. Aronson NE, Wortmann GW, Johnson SC, Jackson JE, Gasser RA Jr, Magill AJ, et al. Safety and efficacy of intravenous sodium stibogluconate in the treatment of leishmaniasis: recent U.S. military experience. Clin Infect Dis 1998;27:1457-64.
11. Martinez S, Marr JJ. Allopurinol in the treatment of American cutaneous leishmaniasis. N Engl J Med 1992;326:741-4.
12. Velez I, Agudelo S, Hendrickx E, Puerta J, Grogl M, Modabber F, et al. Inefficacy of allopurinol as monotherapy for Colombian cutaneous leishmaniasis. A randomized, controlled trial. Ann Intern Med 1997;126:232-6.
13. Esfandiarpour I, Alavi A. Evaluating the efficacy of allopurinol and meglumine antimoniate (Glucan-time) in the treatment of cutaneous leishmaniasis. Int J Dermatol 2002;41:521-4.
14. Llanos-Cuentas A, Echevarria J, Cruz M, La Rosa A, Campos P, Campos M, et al. Efficacy of sodium stibogluconate alone and in combination with allopurinol for treatment of mucocutaneous leishmaniasis. Clin Infect Dis 1997;25:677-84.
15. Navin TR, Arana BA, Arana FE, de Merida AM, Castillo AL, Pozuelos JL. Placebo-controlled clinical trial of meglumine antimonate (glucantime) vs. localized controlled heat in the treatment of cutaneous leishmaniasis in Guatemala. Am J Trop Med Hyg 1990;42:43-50.
16. Velasco-Castrejon O, Walton BC, Rivas-Sanchez B, Garcia MF, Lazaro GJ, et al. Treatment of cutaneous leishmaniasis with localized current field (radio frequency) in Tabasco, Mexico. Am J Trop Med Hyg 1997;57:309-12.
17. Gurei MS, Tatli N, Ozbilge H, Erel O, Seyrek A, Kocyigit A, et al. Efficacy of cryotherapy and intralesional pentostam in treatment of cutaneous leishmaniasis. J Egypt Soc Parasitol 2000;30:169-76.
18. Alrajhi AA, Ibrahim EA, De Vol EB, Khairat M, Faris RM, Maguire JH. Fluconazole for the treatment of cutaneous leishmaniasis caused by Leishmania major. N Engl J Med 2002;346:891-5.
19. Davies CR, Kaye P, Croft SL, Sundar S. Leishmaniasis: new approaches to disease control. BMJ 2003;326:377-82.
20. Sharifi I, FeKri AR, Aflatonian MR, Khamesipour A, Nadim A, Mousavi MR, et al. Randomised vaccine trial of single dose of killed Leishmania major plus BCG against anthroponotic cutaneous leishmaniasis in Bam, Iran. Lancet 1998;351:1540-3.
21. Kroeger A, Avila EV, Morison L. Insecticide impregnated curtains to control domestic transmission of cutaneous leishmaniasis in Venezuela: cluster randomised trial. BMJ 2002;325:810-3.