The P Cytotype in Drosophila melanogaster: A Maternally Transmitted Regulatory State of the Germ Line Associated with Telomeric P Elements

Genetics

Volumn 166, Issue 1, 2004, Pages 243-254

  Simmons, Michael J ^a   Raymond, John D ^a   Niemi, Jarad B ^a   Stuart, Jeremy R ^a   Merriman, Peter J ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GENE PRODUCT; POLYPEPTIDE; PROTEIN TP5; PROTEIN TP6; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL TYPE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE TRANSMISSION; DROSOPHILA MELANOGASTER; EPISTASIS; FEMALE; GENDER; GENE INSERTION; GERM LINE; GONADAL DYSGENESIS; HEREDITY; MALE; NONHUMAN; NUCLEOTIDE REPEAT; P CYTOTYPE; PEPTIDE ANALYSIS; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; REPRESSOR GENE; SINGED GENE; SOMATIC CELL; TAS REPEAT; TELOMERE; VERTICAL TRANSMISSION; X CHROMOSOME;

ALLELES; ANIMALS; CROSSES, GENETIC; DNA TRANSPOSABLE ELEMENTS; DROSOPHILA MELANOGASTER; FEMALE; GERM CELLS; GONADAL DYSGENESIS; MALE; PHENOTYPE; TELOMERE; TRANSPOSASES; X CHROMOSOME;

ANIMALIA; ARACHNIDA; DROSOPHILA MELANOGASTER; EUKARYOTA; HEXAPODA; MELANOGASTER;

EID: 1642325147     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: 10.1534/genetics.166.1.243     Document Type: Article

References (37)

1. ADAMS, M. D., S. E. CELNIKER, R. A. HOLT, C. A. EVANS, J. D. GOCAYNE et al., 2000 The genome sequence of Drosophila melanogaster. Science 287: 2185-2195.
2. BINGHAM, P. M., M. G. KIDWELL and G. M. RUBIN, 1982 The molecular basis of P-M hybrid dysgenesis: the role of the P element, a P strain-specific transposon family. Cell 29: 995-1004.
3. BLACK, D. M., M. S. JACKSON, M. G. KIDWELL and G. A. DOVER, 1987 KP elements repress P-induced hybrid dysgenesis in Drosophila melanogaster. EMBO J. 6: 4125-4135.
4. ENGELS, W. R., 1979a Hybrid dysgenesis in Drosophila melanogaster: rules of inheritance of female sterility. Genet. Res. 33: 219-236.
5. ENGELS, W. R., 1979b Extrachromosomal control of mutability in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 76: 4011-4015.
6. ENGELS, W. R., 1984 A trans-acting product needed for P factor transposition in Drosophila. Science 226: 1194-1196.
7. GLOOR, G. B., C. R. PRESTON, D. M. JOHNSON-SCHLITZ, N. A. NASSIF, R. W. PHILLIS et al., 1993 Type I repressors of P-element mobility. Genetics 135: 81-95.
8. HODGETTS, R. B., and S. L. O'KEEFE, 2001 The mutant phenotype associated with P-element alleles of the vestigial locus in Drosophila melanogaster may be caused by a readthrough transcript initiated at the P-element promoter. Genetics 157: 1665-1672.
9. JACKSON, M. S., D. M. BLACK and G. A. DOVER, 1988 Amplification of KP elements associated with the repression of hybrid dysgenesis in Drosophila melanogaster. Genetics 120: 1003-1013.
10. KARESS, R., and G. M. RUBIN, 1984 Analysis of P transposable element functions in Drosophila. Cell 38: 135-146.
11. KIDWELL, M. G., J. F. KIDWELL and J. A. SVED, 1977 Hybrid dysgenesis in Drosophila melanogaster: a syndrome of aberrant traits including mutation, sterility and male recombination. Genetics 86: 813-833.
12. LASKI, F. A., D. C. RIO and G. M. RUBIN, 1986 Tissue specificity of Drosophila P element transposition is regulated at the level of mRNA splicing. Cell 44: 7-19.
13. LEE, C. C., Y. M. MUL and D. C. RIO, 1996 The Drosophila P-element KP repressor protein dimerizes and interacts with multiple sites on P-element DNA. Mol. Cell. Biol. 16: 5616-5622.
14. LEE, C. C., E. L. BEALL and D. C. RIO, 1998 DNA binding by the KP repressor protein inhibits P-element transposase activity in vivo. EMBO J. 17: 4166-4174.
15. LEMAITRE, B., S. RONSSERAY and D. COEN, 1993 Maternal repression of the P element promoter in the germline of Drosophila melanogaster: a model for the P cytotype. Genetics 135: 149-160.
16. LINDSLEY, D. L., and G. ZIMM, 1992 The Genome of Drosophila melanogaster. Academic Press, New York.
17. MARIN, L., M. LEHMANN, D. NOUAUD, H. IZAABEL, D. ANXOLABÉH̀ ERE et al., 2000 P-element repression in Drosophila melanogaster by a naturally occurring defective telomeric P copy. Genetics 155: 1841-1854.
18. MISRA, S., and D. C. Rio, 1990 Cytotype control of Drosophila P element transposition: the 66 kD protein is a repressor of transposase activity. Cell 62: 269-284.
19. O'HARE, K., and G. M. RUBIN, 1983 Structure of P transposable elements and their sites of insertion and excision in the Drosophila melanogaster genome. Cell 34: 25-35.
20. O'HARE, K., A. DRIVER, S. MCGRATH and D. M. JOHNSON-SCHLITZ, 1992 Distribution and structure of cloned P elements from the Drosophila melanogaster P strain Π2. Genet. Res. 60: 33-41.
21. RASMUSSON, K. E., M. J. SIMMONS, J. D. RAYMOND and C. F. MCLARNON, 1990 Quantitative effects of P elements on hybrid dysgenesis in Drosophila melanogaster. Genetics 124: 647-662.
22. ROBERTSON, H. M., and W. R. ENGELS, 1989 Modified P elements that mimic the P cytotype in Drosophila melanogaster. Genetics 123: 815-824.
23. ROBERTSON, H. M., C. R. PRESTON, R. W. PHILLIS, D. JOHNSON-SCHLITZ, W. K. BENZ et al., 1988 A stable genomic source of P element transposase in Drosophila melanogaster. Genetics 118: 461-470.
24. ROCHE, S., M. SCHIFF and D. C. RIO, 1995 P-element repressor auto-regulation involves germ-line transcriptional repression and reduction of third intron splicing. Genes Dev. 9: 1278-1288.
25. ROIHA, H., G. M. RUBIN and K. O'HARE, 1988 P element insertions and rearrangements at the singed locus of Drosophila melanogaster. Genetics 119: 75-83.
26. RONSSERAY, S., M. LEHMANN and D. ANXOLABÉHÈRE, 1991 The maternally inherited regulation of P elements in Drosophila melanogaster can be elicited by two P copies at cytological site 1A on the X chromosome. Genetics 129: 501-512.
27. RONSSERAY, S., M. LEHMANN, D. NOUAND and D. ANXOLABÉHÈRE, 1996 The regulatory properties of autonomous subtelomeric P elements are sensitive to a Suppressor of variegation in Drosophila melanogaster. Genetics 143: 1663-1674.
28. RONSSERAY, S., L. MARIN, M. LEHMANN and D. ANXOLABÉHÈRE, 1998 Repression of hybrid dysgenesis in Drosophila melanogaster by combinations of telomeric P-element reporters and naturally occurring P elements. Genetics 149: 1857-1866.
29. RONSSERAY, S., A. BOIVIN and D. ANXOLABÉHÈRE, 2001 P-element repression in Drosophila melanogaster by variegating clusters of P-lacZ-white transgenes. Genetics 159: 1631-1642.
30. SIMMONS, M. J., N. A. JOHNSON, T. M. FAHEY, S. M. NELLET and J. D. RAYMOND, 1980 High mutability in male hybrids of Drosophila melanogaster. Genetics 96: 479-490.
31. SIMMONS, M. J., J. D. RAYMOND, K. E. RASMUSSON, L. M. MILLER, C. F. MCLARNON et al., 1990 Repression of P-element-mediated hybrid dysgenesis in Drosophila melanogaster. Genetics 124: 663-676.
32. SIMMONS, M. J., K. J. HALEY, C. D. GRIMES, J. D. RAYMOND and J. B. NIEMI, 2002a A hobo transgene that encodes the P-element transposase in Drosophila melanogaster: autoregulation and cytotype control of transposase activity. Genetics 161: 195-204.
33. SIMMONS, M. J., K. J. HALEY, C. D. GRIMES, J. D. RAYMOND and J. C. L. FONG, 2002b Regulation of P-element transposase activity in Drosophila melanogaster by hobo transgenes that contain KP elements. Genetics 161: 205-215.
34. SIMMONS, M. J., K. J. HALEY and S. J. THOMPSON, 2002c Maternal transmission of P element transposase activity in Drosophila melanogaster depends on the last P intron. Proc. Natl. Acad. Sci. USA 99: 9306-9309.
35. STUART, J. R., K. J. HALEY, D. SWEDZINSKI, S. LOCKNER, P. E. KOCIAN et al., 2002 Telomeric P elements associated with cytotype regulation of the P transposon family in Drosophila melangoaster. Genetics 162: 1641-1654.
36. SVED, J. A., 1987 Hybrid dysgenesis in Drosophila melanogaster: evidence from sterility and Southern hybridization tests that P cytotype is not maintained in the absence of chromosomal P factors. Genetics 115: 121-127.
37. WILLIAMS, J. A., S. S. PAPPU and J. B. BELL, 1988 Suppressible P-element alleles of the vestigial locus in Drosophila melanogaster. Mol. Gen. Genet. 212: 370-374.