Influence of sedation on morbidity and mortality in the intensive care unit

Sao Paulo Medical Journal

Volumn 122, Issue 1, 2004, Pages 8-11

  Rodrigues Jr , Geraldo Rolim ^a   Gomes do Amaral, José Luiz ^b  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

APACHE; Complications; Intensive care unit; Mortality

Indexed keywords

ADULT; ARTICLE; CAUSE OF DEATH; CONTROLLED STUDY; DECUBITUS; DEEP VEIN THROMBOSIS; DISEASE ASSOCIATION; DISEASE SEVERITY; FATALITY; FEMALE; HEALTH STATUS; HIGH RISK PATIENT; HOSPITAL INFECTION; HOSPITALIZATION; HUMAN; INCIDENCE; INFECTION RISK; INTENSIVE CARE; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; MORBIDITY; MORTALITY; PATIENT SELECTION; PROGNOSIS; PROSPECTIVE STUDY; SEDATION; STATISTICAL SIGNIFICANCE; TEACHING HOSPITAL;

EID: 1642323619     PISSN: 15163180     EISSN: None     Source Type: Journal    
DOI: 10.1590/s1516-31802004000100003     Document Type: Article

References (22)

1. Amaral JLG, Rodrigues Jr GR, Rocha RGA, et al. Sedação. In: Amaral JLG, editor. Clínicas Brasileiras de Medicina Intensiva: Sedação. Analgesia e Bloqueio Neuromuscular em UTI. São Paulo: Editor Atheneu; 1997.p.75-94.
2. Dobb GJ, Murphy DF. Sedation and Analgesia during Intensive Care. Clin Anaesth 1985;3(4):1055-83.
3. Bion JF, Ledingham IM. Sedation in intensive care - a postal survey. Intensive Care Med 1987;13(3):215-6.
4. Siegel S. Estatística no Parametrica. Ciudad de Mexico: Ed. Trillas Mexico; 1975.p.346.
5. Ramsay MA, Savage TM, Simpson BR, Goodwin R. Controlled sedation with alphaxalone-alphadolone. Br Med J 1974; 2(920):656-9.
6. Aitkenhead AR. Analgesia and sedation in intensive care. Br J Anaesth 1989;63(2):196-206.
7. Buchanan N, Cane RD. Drug utilization in a general intensive care unit. Intensive Care Med 1978;4(2):75-7.
8. Ledingham IM, Watt I. Influence of sedation on mortality in critically ill multiple trauma patients. Lancet 1983; 1(8336):1270.
9. Watt I, Ledingham IM. Mortality amongst multiple trauma patients admitted to an intensive therapy unit. Anaesthesia 1984;39(10)973-81.
10. Ledingham IM, Bion JF, Newman LH, McDonald JC, Wallace PG. Mortality and morbidity amongst scaled sedated intensive care patients. Resuscitation 1988;16(Suppl):S69-77.
11. Etomnidate. Lancet 1983;2(8342):168-9.
12. Tubaro E, Borelli, G, Croce C, Cavallo G, Santiangeli C. Effect of morphine on resistance to infection. J Infect Dis 1983;148(4):656-66.
13. Moudgil GC. Effect or premedicants, intravenous anaesthetic agents an local anaesthetics on phagocytosis in vitro. Can Anaesth Soc J 1981;28(6):597-602.
14. Hole A. Depression of monocytes and lymphocytes by stress-related humoral factors and anaesthetic-related drugs. Acta Anaesthesiol Scand 1984;28(3):280-6.
15. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. Apache II: a severity of disease classification system. Crit Care Med 1985;13(10):818-29.
16. Bion JF, Logan BK, Newman PM, Brodie MJ, Oliver JS, Aitchison TC, Ledingham JM. Sedation in intensive care morphine and renal function. Intensive Care Med 1986;12(5)359-65.
17. Wallace PGM, Bion JF, Ledingham IM. The changing face of sedative practice. In: Ledingham IM, editor. Recent Advances in Critical Care Medicine. Edinburgh: Churchill-Livingstone; 1988. p.70-93.
18. Moritz RD, Goldwasser RS. O uso de analgésicos, sedativos e bloqueadores neuromuscular nas UTIs brasileiras. [Use of sedatives, analgesics and neuromuscular blocking agents in Brasil ICUs]. Rev Bras Ter Intensiva 1999;11(4):139-45.
19. Shapiro BA, Warren J, Egol Ab, et al. Practice parameters for intravenous analgesia and sedation for adult patients in the intensive care unit: an executive summary. Society of Critical Care Medicine. Crit Care Med 1995;23(9):1596-600.
20. Nasraway Jr SA. Use of Sedative Medications in the Intensive Care Unit. Sem Resp Crit Care Med 2001;22(2):165-74.
21. Amaral JLG, Réa Neto A, Conceição NA, et al. I Consenso Brasileiro sobre Sedação, analgesia e bloqueio neuromuscular em Terapia Intensiva. In: Amaral JLG, editor. Clínicas Brasileiras de Medicina Intensiva. Sedação, Analgesia e Bloqueio Neuromuscular em. UTI. São Paulo: Editora Athene 1997.p.241-55.
22. Amaral JLG, Issy, AM, Conceição NA, et al. Recomendações da Associação Brasileira de Medicina Intensiva Brasileira sobre analgesia, sedação e bloqueio neuromuscular em Terapia Intensiva. São Paulo: AMIB; 1999.