Muscle mechanoreflex induces the pressor response by resetting the arterial baroreflex neural arc

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 286, Issue 4 55-4, 2004, Pages

  Yamamoto, Kenta ^a   Kawada, Toru ^a   Kamiya, Atsunori ^a   Takaki, Hiroshi ^a   Miyamoto, Tadayoshi ^a,b   Sugimachi, Masaru ^a   Sunagawa, Kenji ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b Japan Association for the Advancement of Medical Equipment   (Japan)

Author keywords

Arterial pressure; Baroreflex equilibrium diagram; Exercise; Exercise pressor reflex; Sympathetic nerve activity

Indexed keywords

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; CAROTID SINUS; CAROTID SINUS PRESSORECEPTOR; EXERCISE; HINDLIMB; MUSCLE REFLEX; MUSCLE STRETCHING; MUSCLE TONE; NEGATIVE FEEDBACK; NONHUMAN; PRESSOR RESPONSE; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; SYMPATHETIC TONE; VASODILATATION;

ACTION POTENTIALS; ALGORITHMS; ANIMALS; ARTERIES; BAROREFLEX; BIOMECHANICS; CAROTID SINUS; HINDLIMB; MUSCLE CONTRACTION; MUSCLE SPINDLES; MUSCLE, SKELETAL; RABBITS; SYMPATHETIC NERVOUS SYSTEM;

EID: 1642321741     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00801.2003     Document Type: Article

References (42)

1. Aicher SA, Kurucz OS, Reis DJ, and Milner TA. Nucleus tractus solitarius efferent terminals synapse on neurons in the caudal ventrolateral medulla that project to the rostral ventrolateral medulla. Brain Res 693: 51-63, 1995.
2. Bauer RM, Iwamoto GA, and Waldrop TG. Discharge patterns of ventrolateral medullary neurons during muscular contraction. Am J Physiol Regul Integr Comp Physiol 259: R606-R611, 1990.
3. Bauer RM, Waldrop TG, Iwamoto GA, and Holzwarth MA. Properties of ventrolateral medullary neurons that respond to muscular contraction. Brain Res Bull 28: 167-178, 1992.
4. Buckwalter JB, Naik JS, Valic Z, and Clifford PS. Exercise attenuates α-adrenergic receptor responsiveness in skeletal muscle vasculature. J Appl Physiol 90: 172-178, 2001.
5. Fadel PJ, Ogoh S, Watenpaugh DE, Wasmund W, Olivencia-Yurvati A, Smith ML, and Raven PB. Carotid baroreflex regulation of sympathetic nerve activity during dynamic exercise in humans. Am J Physiol Heart Circ Physiol 280: H1383-H1390, 2001.
6. Gallagher KM, Fadel PJ, Smith SA, Norton KH, Querry RG, Olivencia-Yurvati A, and Raven PB. Increases in intramuscular pressure raise arterial blood pressure during dynamic exercise. J Appl Physiol 91: 2351-2358, 2001.
7. Gallagher KM, Fadel PJ, Stromstad M, Ide K, Smith SA, Querry RG, Raven PB, and Secher NH. Effects of exercise pressor reflex activation on carotid baroreflex function during exercise in humans. J Physiol 533: 871-880, 2001.
8. Gallagher KM, Fadel PJ, Stromstad M, Ide K, Smith SA, Querry RG, Raven PB, and Secher NH. Effects of partial neuromuscular blockade on carotid baroreflex function during exercise in humans. J Physiol 533: 861-870, 2001.
9. Hayes SG and Kaufman MP. Gadolinium attenuates exercise pressor reflex in cats. Am J Physiol Heart Circ Physiol 280: H2153-H2161, 2001.
10. Hayes SG and Kaufman MP. MLR stimulation and exercise pressor reflex activate different renal sympathetic fibers in decerebrate cats. J Appl Physiol 92: 1628-1634, 2002.
11. Howard MG and DiCarlo SE. Reduced vascular responsiveness after a single bout of dynamic exercise in the conscious rabbit. J Appl Physiol 73: 2662-2667, 1992.
12. Howard MG, DiCarlo SE, and Stallone JN. Acute exercise attenuates phenylephrine-induced contraction of rabbit isolated aortic rings. Med Sci Sports Exerc 24: 1102-1107, 1992.
13. Iellamo F, Legramante JM, Raimondi G, and Peruzzi G. Baroreflex control of sinus node during dynamic exercise in humans: effects of central command and muscle reflexes. Am J Physiol Heart Circ Physiol 272: H1157-H1164, 1997.
14. Kamiya A, Michikami D, Fu Q, Niimi Y, Iwase S, Mano T, and Suzumura A. Static handgrip exercise modifies arterial baroreflex control of vascular sympathetic outflow in humans. Am J Physiol Regul Integr Comp Physiol 281: R1134-R1139, 2001.
15. Kaufman MP and Forster HV. Reflexes controlling circulatory, ventilatory and airway responses to exercise. In: Handbook of Physiology. Exercise: Regulation and Integration of Multiple Systems. Control of Respiratory and Cardiovascular Systems. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 12, pt. II, chapt. 10, p. 381-447.
16. Kawada T, Shishido T, Inagaki M, Tatewaki T, Zheng C, Yanagiya Y, Sugimachi M, and Sunagawa K. Differential dynamic baroreflex regulation of cardiac and renal sympathetic nerve activities. Am J Physiol Heart Circ Physiol 280: H1581-H1590, 2001.
17. Kawada T, Shishido T, Inagaki M, Zheng C, Yanagiya Y, Uemura K, Sugimachi M, and Sunagawa K. Estimation of baroreflex gain using a baroreflex equilibrium diagram. Jpn J Physiol 52: 21-29, 2002.
18. Kawada T, Uemura K, Kashihara K, Jin Y, Li M, Zheng C, Sugimachi M, and Sunagawa K. Uniformity in dynamic baroreflex regulation of left and right cardiac sympathetic nerve activities. Am J Physiol Regul Integr Comp Physiol 284: R1506-R1512, 2003.
19. Kent BB, Drane JW, Blumenstein B, and Manning JW. A mathematical model to assess changes in the baroreceptor reflex. Cardiology 57: 295-310, 1972.
20. Leshnower BG, Potts JT, Garry MG, and Mitchell JH. Reflex cardiovascular responses evoked by selective activation of skeletal muscle ergoreceptors. J Appl Physiol 90: 308-316, 2001.
21. Matsukawa K, Wall PT, Wilson EB, and Mitchell JH. Reflex responses of renal nerve activity during isometric muscle contraction in cats. Am J Physiol Heart Circ Physiol 259: H1380-H1388, 1990.
22. McCloskey DI and Mitchell JH. Reflex cardiovascular and respiratory responses originating in exercising muscle. J Physiol 224: 173-186, 1972.
23. McIlveen SA, Hayes SG, and Kaufman MP. Both central command and exercise pressor reflex reset carotid sinus baroreflex. Am J Physiol Heart Circ Physiol 280: H1454-H1463, 2001.
24. Melcher A and Donald DE. Maintained ability of carotid baroreflex to regulate arterial pressure during exercise. Am J Physiol Heart Circ Physiol 241: H838-H849, 1981.
25. Mense S and Stahnke M. Responses in muscle afferent fibres of slow conduction velocity to contractions and ischaemia in the cat. J Physiol 342: 383-397, 1983.
26. Miki K, Yoshimoto M, and Tanimizu M. Acute shifts of baroreflex control of renal sympathetic nerve activity induced by treadmill exercise in rats. J Physiol 548: 313-322, 2003.
27. Mitchell JH, Kaufman MP, and Iwamoto GA. The exercise pressor reflex: its cardiovascular effects, afferent mechanisms, and central pathways. Annu Rev Physiol 45: 229-242, 1983.
28. Mohrman DE and Heller LJ. Cardiovascular Physiology (4th ed.). New York: McGraw-Hill, 1997, p. 158-230.
29. Norton KH, Boushel R, Strange S, Saltin B, and Raven PB. Resetting of the carotid arterial baroreflex during dynamic exercise in humans. J Appl Physiol 87: 332-338, 1999.
30. Papelier Y, Escourrou P, Gauthier JP, and Rowell LB. Carotid baroreflex control of blood pressure and heart rate in men during dynamic exercise. J Appl Physiol 77: 502-506, 1994.
31. Potts JT and Li J. Interaction between carotid baroreflex and exercise pressor reflex depends on baroreceptor afferent input. Am J Physiol Heart Circ Physiol 274: H1841-H1847, 1998.
32. Potts JT and Mitchell JH. Rapid resetting of carotid baroreceptor reflex by afferent input from skeletal muscle receptors. Am J Physiol Heart Circ Physiol 275: H2000-H2008, 1998.
33. Potts JT, Paton JF, Mitchell JH, Garry MG, Kline G, Anguelov PT, and Lee SM. Contraction-sensitive skeletal muscle afferents inhibit arterial baroreceptor signalling in the nucleus of the solitary tract: role of intrinsic GABA interneurons. Neuroscience 119: 201-214, 2003.
34. Potts JT, Shi XR, and Raven PB. Carotid baroreflex responsiveness during dynamic exercise in humans. Am J Physiol Heart Circ Physiol 265: H1928-H1938, 1993.
35. Rowell LB and O'Leary DS. Reflex control of the circulation during exercise: chemoreflexes and mechanoreflexes. J Appl Physiol 69: 407-418, 1990.
36. Rowell LB, O'Leary DS, and Kellogg DS. Integration of cardiovascular control system in dynamic exercise. In: Handbook of Physiology. Exercise: Regulation and Integration of Multiple Systems. Bethesda, MD: Am. Physiol. Soc., sect. 12, pt. II, chapt. 17, 1996, p. 770-838.
37. Ruble SB, Valic Z, Buckwalter JB, and Clifford PS. Dynamic exercise attenuates sympathetic responsiveness of canine vascular smooth muscle. J Appl Physiol 89: 2294-2299, 2000.
38. Sato T, Kawada T, Inagaki M, Shishido T, Takaki H, Sugimachi M, and Sunagawa K. New analytic framework for understanding sympathetic baroreflex control of arterial pressure. Am J Physiol Heart Circ Physiol 276: H2251-H2261, 1999.
39. Stebbins CL, Brown B, Levin D, and Longhurst JC. Reflex effect of skeletal muscle mechanoreceptor stimulation on the cardiovascular system. J Appl Physiol 65: 1539-1547, 1988.
40. Sun MK and Guyenet PG. GABA-mediated baroreceptor inhibition of reticulospinal neurons. Am J Physiol Regul Integr Comp Physiol 249: R672-R680, 1985.
41. Victor RG, Rotto DM, Pryor SL, and Kaufman MP. Stimulation of renal sympathetic activity by static contraction: evidence for mechanoreceptor-induced reflexes from skeletal muscle. Circ Res 64: 592-599, 1989.
42. Waldrop TG, Eldridge FL, Iwamoto GA, and Mitchell JH. Central neural control of respiration and circulation during exercise, In: Handbook of Physiology. Exercise: Regulation and Integration of Multiple Systems. Control of Respiratory and Cardiovascular Systems. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 12, pt. II, chapt. 9, p. 333-380.