NMDA receptors in nucleus tractus solitarii are linked to soluble guanylate cyclase

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 286, Issue 4 55-4, 2004, Pages

  Chianca Jr , Deoclecio A ^a,b   Lin, Li Hsien ^a   Dragon, Deidre Nitschke ^a   Talman, William T ^a  

^a UNIVERSITY OF IOWA   (United States)

^b FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

Author keywords

Baroreflex; Ionotropic receptor

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CHLORALOSE; GUANYLATE CYCLASE; IONOTROPIC RECEPTOR; IONOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SOLUBLE GUANYLATE CYCLASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; CARDIOVASCULAR RESPONSE; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; SOLITARY TRACT NUCLEUS;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; AMINOQUINOLINES; ANIMALS; BAROREFLEX; BIOTRANSFORMATION; BLOOD PRESSURE; CYCLOLEUCINE; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; GUANYLATE CYCLASE; MALE; MICROINJECTIONS; N-METHYLASPARTATE; NITRIC OXIDE; OXADIAZOLES; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SOLITARY NUCLEUS; STEREOTAXIC TECHNIQUES;

EID: 1642311877     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00236.2003     Document Type: Article

References (78)

1. + currents in frog cardiac myocytes. Br J Pharmacol 121: 1369-1377, 1997.
2. Abrahams TP, Hornby PJ, Chen K, Dasilva AMT, and Gillis RA. The non-NMDA subtype of excitatory amino acid receptor plays the major role in control of cardiovascular function by the subretrofacial nucleus in cats. J Pharmacol Exp Ther 270: 424-432, 1994.
3. Andresen MC and Yang M. Non-NMDA receptors mediate sensory afferent synaptic transmission in medial nucleus tractus solitarius. Am J Physiol Heart Circ Physiol 259: H1307-H1311, 1990.
4. Bredt DS and Snyder SH. Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci USA 86: 9030-9033, 1989.
5. Brenman JE and Bredt DS. Synaptic signaling by nitric oxide. Curr Opin Neurobiol 7: 374-378, 1997.
6. Brodin L, Shupliakov O, and Grillner SE. Central glutamatergic transmission: a view from the presynaptic axon. Adv Second Messenger Phosphoprotein Res 29: 205-222, 1994.
7. Chan JYH, Yang SM, and Chan SHH. Mediation by N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors in the expression of Fos protein at the nucleus tractus solitarii in response to baroreceptor activation in the rat. Neuroscience 83: 93-105, 1998.
8. Ciriello J. Brainstem projections of aortic baroreceptor afferent fibers in the rat. Neurosci Lett 36: 37-42, 1983.
9. Ciriello J, Hrycyshyn AW, and Calaresu FR. Glossopharyngeal and vagal afferent projections to the brain stem of the cat: a horseradish peroxidase study. J Auton Nerv Syst 4: 63-79, 1981.
10. Claps A, Torrealba F, and Calderón F. Segregation of coarse and fine glossopharyngeal axons in the visceral nucleus of the tractus solitarius of the cat. Brain Res 489: 80-92, 1989.
11. Di Paola ED, Vidal MJ, and Nisticò G. L-Glutamate evokes the release of an endothelium-derived relaxing factor-like substance from the rat nucleus tractus solitarius. J Cardiovasc Pharmacol 17, Suppl 3: S269-S272, 1991.
12. Doba N and Reis DJ. Acute fulminating neurogenic hypertension produced by brainstem lesions in the rat. Circ Res 32: 584-593, 1973.
13. East SJ and Garthwaite J. NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the L-arginine-nitric oxide pathway. Neurosci Lett 123: 17-19, 1991.
14. Foley CM, Vogl HW, Mueller PJ, Hay M, and Hasser EM. Cardiovascular response to group 1 metabotropic glutamate receptor activation in NTS. Am J Physiol Regul Integr Comp Physiol 276: R1469-R1478, 1999.
15. 3H]cGMP binding, by the rat vagus nerve. Brain Res 878: 240-246, 2000.
16. Garthwaite J and Boulton CL. Nitric oxide signaling in the central nervous system. Annu Rev Physiol 57: 683-706, 1995.
17. Glaum SR and Miller RJ. Metabotropic glutamate receptors depress afferent excitatory transmission in the rat nucleus tractus solitarii. J Neurophysiol 70: 2669-2672, 1993.
18. Glaum SR and Miller RJ. Zinc protoporphyrin-IX blocks the effects of metabotropic glutamate receptor activation in the rat nucleus tractus solitarii. Mol Pharmacol 43: 965-969, 1993.
19. Gordon FJ and Leone C. Non-NMDA receptors in the nucleus of the tractus solitarius play the predominant role in mediating aortic baroreceptor reflexes. Brain Res 568: 319-322, 1991.
20. Gordon FJ and Talman WT. Role of excitatory amino acids and their receptors in bulbospinal control of cardiovascular function. In: Central Neural Mechanisms in Cardiovascular Regulation, edited by Kunos G and Ciriello J. New York: Birkhauser, 1992, vol. 2, p. 209-225.
21. + requirement. J Neurochem 57: 1488-1500, 1991.
22. Guiramand J, Vignes M, and Récasens M. A specific transduction mechanism for the glutamate action on phosphoinositide metabolism via the quisqualate metabotropic receptor in rat brain synaptoneurosomes: II. Calcium dependency, cadmium inhibition. J Neurochem 57: 1501-1509, 1991.
23. Harada S, Tokunaga S, Momohara M, Masaki H, Tagawa T, Imaizumi T, and Takeshita A. Inhibition of nitric oxide formation in the nucleus tractus solitarius increases renal sympathetic nerve activity in rabbits. Circ Res 72: 511-516, 1993.
24. Hollmann M and Heinemann S. Cloned glutamate receptors. Annu Rev Neurosci 17: 31-108, 1994.
25. Hume RI, Dingledine R, and Heinemann SF. Identification of a site in glutamate receptor subunits that controls calcium permeability. Science 253: 1028-1031, 1991.
26. Ignarro LJ. Heme-dependent activation of guanylate cyclase by nitric oxide: a novel signal transduction mechanism. Blood Vessels 28: 67-73, 1991.
27. Ingi T, Cheng J, and Ronnett GV. Carbon monoxide: an endogenous modulator of the nitric oxide-cyclic GMP signaling system. Neuron 16: 835-842, 1996.
28. Kalia M and Mesulam MM. Brain stem projections of sensory and motor components of the vagus complex in the cat. I. The cervical vagus and nodose ganglion. J Comp Neurol 193: 435-465, 1980.
29. Kalia M and Mesulam MM. Brain stem projections of sensory and motor components of the vagus complex in the cat. II. Laryngeal, tracheobronchial, pulmonary, cardiac, and gastrointestinal branches. J Comp Neurol 193: 467-508, 1980.
30. Katusic ZS and Cosentino F. Nitric oxide synthase: from molecular biology to cerebrovascular physiology. News Physiol Sci 9: 64-67, 1994.
31. Kharitonov VG, Sharma VS, Pilz RB, Magde D, and Koesling D. Basis of guanylate cyclase activation by carbon monoxide. Proc Natl Acad Sci USA 92: 2568-2571, 1995.
32. Kiedrowski L, Costa E, and Wroblewski JT. Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells. J Neurochem 58: 335-341, 1992.
33. Kontos HA and Wei EP. Hydroxyl radical-dependent inactivation of guanylate cyclase in cerebral arterioles by methylene blue and by LY83583. Stroke 24: 427-434, 1993.
34. Lawrence AJ. Neurotransmitter mechanisms of rat vagal afferent neurons. Clin Exp Pharmacol Physiol 22: 869-873, 1995.
35. Lawrence AJ and Jarrott B. Nitric oxide increases interstitial excitatory amino acid release in the rat dorsomedial medulla oblongata. Neurosci Lett 151: 126-129, 1993.
36. Lawrence AJ and Jarrott B. L-Glutamate as a neurotransmitter at baroreceptor afferents: evidence from in vivo microdialysis. Neuroscience 58: 585-591, 1994.
37. Lei SZ, Pan ZH, Aggarwal SK, Chen HSV, Hartman J, Sucher NJ, and Lipton SA. Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex. Neuron 8: 1087-1099, 1992.
38. Leone C and Gordon FJ. Is L-glutamate a neurotransmitter of baroreceptor information in the nucleus of the tractus solitarius? J Pharmacol Exp Ther 250: 953-962, 1989.
39. Lewis SJ, Machado BH, Ohta H, and Talman WT. Processing of cardiopulmonary afferent input within the nucleus tractus solitarii involves activation of soluble guanylate cyclase. Eur J Pharmacol 203: 327-328, 1991.
40. Lewis SJ, Ohta H, Machado B, Bates JN, and Talman WT. Microinjection of S-nitrosocysteine into the nucleus tractus solitarii decreases arterial pressure and heart rate via activation of soluble guanylate cyclase. Eur J Pharmacol 202: 135-136, 1991.
41. Lin HC, Kang BH, Wan FJ, Huang ST, and Tseng CJ. Reciprocal regulation of nitric oxide and glutamate in the nucleus tractus solitarii of rats. Eur J Pharmacol 407: 83-89, 2000.
42. Lin HC, Wan FJ, and Tseng CJ. Modulation of cardiovascular effects produced by nitric oxide and ionotropic glutamate receptor interaction in the nucleus tractus solitarii of rats. Neuropharmacology 38: 935-941, 1999.
43. Lin LH, Cassell MD, Sandra A, and Talman WT. Direct evidence for nitric oxide synthase in vagal afferents to the nucleus tractus solitarii. Neuroscience 84: 549-558, 1998.
44. Lin LH, Emson PC, and Talman WT. Apposition of neuronal elements containing nitric oxide synthase and glutamate in the nucleus tractus solitarii of rat: a confocal microscopic analysis. Neuroscience 96: 341-350, 2000.
45. Lin LH and Talman WT. N-methyl-D-aspartate receptors on neurons that synthesize nitric oxide in rat nucleus tractus solitarii. Neuroscience 100: 581-588, 2000.
46. Lin LH and Talman WT. Colocalization of GluR1 and neuronal nitric oxide synthase in rat nucleus tractus solitarii neurons. Neuroscience 106: 801-809, 2001.
47. Lin LH and Talman WT. Coexistence of NMDA and AMPA receptor subunits with nNOS in the nucleus tractus solitarii of rat. J Chem Neuroanat 24: 287-296, 2002.
48. Liu Z, Chen CY, and Bonham AC. Metabotropic glutamate receptors depress vagal and aortic baroreceptor signal transmission in the NTS. Am J Physiol Heart Circ Physiol 275: H1682-H1694, 1998.
49. Lo WC, Lin HC, Ger LP, Tung CS, and Tseng CJ. Cardiovascular effects of nitric oxide and N-methyl-D-aspartate receptors in the nucleus tractus solitarii of rats. Hypertension 30: 1499-1503, 1997.
50. Luo D, Das S, and Vincent SR. Effects of methylene blue and LY83583 on neuronal nitric oxide synthase and NADPH-diaphorase. Eur J Pharmacol 290: 247-251, 1995.
51. Machado BH and Bonagamba LGH. Microinjection of S-nitrosocysteine into the nucleus tractus solitarii of conscious rats decreases arterial pressure but L-glutamate does not. Eur J Pharmacol 221: 179-182, 1992.
52. Matsuo I, Hirooka Y, Hironaga K, Eshima K, Shigematsu H, Shihara M, Sakai K, and Takeshita A. Glutamate release via NO production evoked by NMDA in the NTS enhances hypotension and bradycardia in vivo. Am J Physiol Regul Integr Comp Physiol 280: R1285-R1291, 2001.
53. Mayer B, Brunner F, and Schmidt K. Inhibition of nitric oxide synthesis by methylene blue. Biochem Pharmacol 45: 367-374, 1993.
54. Meeley MP, Underwood MD, Talman WT, and Reis DJ. Content and in vitro release of endogenous amino acids in the area of the nucleus of the solitary tract of the rat. J Neurochem 53: 1807-1817, 1989.
55. Moncada S. The 1991 Ulf von Euler Lecture. The L-arginine: nitric oxide pathway. Acta Physiol Scand 145: 201-227, 1992.
56. Nakanishi S, Nakajima Y, Masu M, Ueda Y, Nakahara K, Watanabe D, Yamaguchi S, Kawabata S, and Okada M. Glutamate receptors: brain function and signal transduction. Brain Res Brain Res Rev 26: 230-235, 1998.
57. Obata K. Biochemistry and physiology of amino acid transmitters. In: Handbook of Physiology. The Nervous System. Bethesda, MD: Am. Physiol. Soc., 1977, sect. 1, vol. I, pt. 1, chapt. 17, p. 625-650.
58. Ogawa H, Mizusawa A, Kikuchi Y, Hida W, Miki H, and Shirato K. Nitric oxide as a retrograde messenger in the nucleus tractus solitarii of rats during hypoxia. J Physiol 486: 495-504, 1995.
59. Ohta H, Li X, and Talman WT. Release of glutamate in the nucleus tractus solitarii in response to baroreflex activation in rats. Neuroscience 74: 29-37, 1996.
60. Ohta H and Talman WT. Both NMDA and non-NMDA receptors in the NTS participate in the baroreceptor reflex in rats. Am J Physiol Regul Integr Comp Physiol 267: R1065-R1070, 1994.
61. Pawloski-Dahm C and Gordon FJ. Evidence for a kynurenate-insensitive glutamate receptor in nucleus tractus solitarii. Am J Physiol Heart Circ Physiol 262: H1611-H1615, 1992.
62. Prezeau L, Manzoni O, Homburger V, Sladeczek F, Curry K, and Bockaert J. Characterization of a metabotropic glutamate receptor: Direct negative coupling to adenylyl cyclase and involvement of a pertussis toxin-sensitive G protein. Proc Natl Acad Sci USA 89: 8040-8044, 1992.
63. Sladeczek F, Recasens M, and Bockaert J. A new mechanism for glutamate receptor action: phosphoinositide hydrolysis. Trends Neurosci 11: 545-549, 1988.
64. Southam E, East SJ, and Garthwaite J. Excitatory amino acid receptors coupled to the nitric oxide/cyclic GMP pathway in rat cerebellum during development. J Neurochem 56: 2072-2081, 1991.
65. Southam E and Garthwaite J. The nitric oxide-cyclic GMP signalling pathway in rat brain. Neuropharmacology 32: 1267-1277, 1993.
66. Sugiyama H, Ito I, and Watanabe M. Glutamate receptor subtypes may be classified into two major categories: a study on Xenopus oocytes injected with rat brain mRNA. Neuron 3: 129-132, 1989.
67. Sundqvist T and Axelsson KL. The cGMP modulator, LY83583 alters oxygen metabolites differently in cultured endothelial cells and isolated neutrophilic granulocytes. Pharmacol Toxicol 72: 169-174, 1993.
68. Tagawa T, Imaizumi T, Harada S, Endo T, Shiramoto M, Hirooka Y, and Takeshita A. Nitric oxide influences neuronal activity in the nucleus tractus solitarius of rat brainstem slices. Circ Res 75: 70-76, 1994.
69. Talman WT. Kynurenic acid microinjected into the nucleus tractus solitarius of rat blocks the arterial baroreflex but not responses to glutamate. Neurosci Lett 102: 247-252, 1989.
70. Talman WT, Nitschke Dragon D, and Lin LH. Cardiovascular responses to glutamate linked to neuronal nitric oxide synthesis (Abstract). Soc Neurosci Abst 24: 1028, 1998.
71. Talman WT, Nitschke Dragon D, Ohta H, and Lin LH. Nitroxidergic influences on cardiovascular control by NTS: a link with glutamate. Ann NY Acad Sci 940: 169-178, 2001.
72. Talman WT, Perrone MH, and Reis DJ. Evidence for L-glutamate as the neurotransmitter of baroreceptor afferent nerve fibers. Science 209: 813-815, 1980.
73. Tseng CJ, Liu HY, Lin HC, Ger LP, Tung CS, and Yen MH. Cardiovascular effects of nitric oxide in the brain stem nuclei of rats. Hypertension 27: 36-42, 1996.
74. Vardhan A, Kachroo A, and Sapru HN. Excitatory amino acid receptors in commissural nucleus of the NTS mediate carotid chemoreceptor responses. Am J Physiol Regul Integr Comp Physiol 264: R41-R50, 1993.
75. Vitagliano S, Berrino L, D'Amico M, Maione S, De Novellis V, and Rossi F. Involvement of nitric oxide in cardiorespiratory regulation in the nucleus tractus solitarii. Neuropharmacology 35: 625-631, 1996.
76. Zhang J and Mifflin SW. Influences of excitatory amino acid receptor agonists on nucleus of the solitary tract neurons receiving aortic depressor nerve inputs. J Pharmacol Exp Ther 282: 639-647, 1997.
77. Zhang W and Mifflin SW. Excitatory amino acid receptors within NTS mediate arterial chemoreceptor reflexes in rats. Am J Physiol Heart Circ Physiol 265: H770-H773, 1993.
78. Zuo Z, Tichotsky A, and Johns RA. Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics. Neuroscience 93: 1167-1172, 1999.