α2-Adrenergic receptor inhibition of cAMP accumulation is transformed to facilitation by tumor necrosis factor-α

Brain Research

Volumn 1004, Issue 1-2, 2004, Pages 212-216

  Renauld, Amy E ^a   Ignatowski, Tracey A ^a   Spengler, Robert N ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

2 Adrenergic receptor; Catecholamine receptors; Cyclic adenosine monophosphate; Neuron; Neurotransmitters, modulators, transporters, and receptors; Tumor necrosis factor

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CYCLIC AMP; FORSKOLIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; AUTOCRINE EFFECT; BIOACCUMULATION; CELL ACTIVITY; CELL LINE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXPOSURE; HUMAN; HUMAN CELL; NERVE CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; STIMULATION;

CELL LINE, TUMOR; CYCLIC AMP; HUMANS; RECEPTORS, ADRENERGIC, ALPHA-2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 1642304164     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.01.029     Document Type: Article

References (35)

1. Banks W.A., Kastin A.J., Broadwell R.D. Passage of cytokines across the blood-brain barrier. Neuroimmunomodulation. 2:1995;241-248.
2. Biedler J.L., Roffler-Tarlov S., Schachner M., Freedman L.S. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38:1978;3751-3757.
3. Breder C.D., Tsujimoto M., Terano Y., Scott D.W., Saper C.B. Distribution and characterization of tumor necrosis factor-α-like immunoreactivity in the murine central nervous system. J. Comp. Neurol. 337:1993;543-567.
4. Chabre O., Conklin B.R., Brandon S., Bourne H.R., Limbird L.E. Coupling of the alpha 2A-adrenergic receptor to multiple G-proteins. A simple approach for estimating receptor-G-protein coupling efficiency in a transient expression system. J. Biol. Chem. 269(8):1994;5730-5734.
5. 2-mediated cAMP production during neuronal differentiation of human neuroblastoma SK-N-BE(2)C cells. J. Neurochem. 79:2001;303-310.
6. Covey W.C., Ignatowski T.A., Knight P.R., Spengler R.N. Brain-derived TNFα: involvement in neuroplastic changes implicated in the conscious perception of persistent pain. Brain Res. 859:2000;113-122.
7. Dantzer R., Konsman J.P., Bluthe R.M., Kelley K.W. Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent? Auton. Neurosci. 85:2000;60-65.
8. Dixon W.R., Mosimann W.F., Weiner N. The role of presynaptic feedback mechanisms in regulation of norepinephrine release by nerve stimulation. J. Pharmacol. Exp. Ther. 209:1979;196-204.
9. Eason M.G., Liggett S.B. Identification of a Gs coupling domain in the amino terminus of the third intracellular loop of the alpha 2A-adrenergic receptor. Evidence for distinct structural determinants that confer Gs versus Gi coupling. J. Biol. Chem. 270(42):1995;24753-24760.
10. 2-adrenergic receptors to two G-proteins with opposing effects. J. Biol. Chem. 22(5):1992;15795-15801.
11. Elenkov I.J., Kovacs K., Duda E., Stark E., Vizi E.S. Presynaptic inhibitory effect of TNF-α on the release of noradrenaline in isolated median eminence. J. Neuroimmunol. 41:1992;117-120.
12. Goehler L.E., Gaykema R.P., Hansen M.K., Anderson K., Maier S.F., Watkins L.R. Vagal immune-to-brain communication: a visceral chemosensory pathway. Auton. Neurosci. 85:2000;49-59.
13. Ignatowski T.A., Spengler R.N. Tumor necrosis factor-alpha: pre-synaptic sensitivity is modified after antidepressant drug administration. Brain Res. 665:1994;239-299.
14. Ignatowski T.A., Chou R.C., Spengler R.N. Changes in noradrenergic sensitivity to tumor necrosis factor-α in brains of rats administered clonidine. J. Neuroimmunol. 70:1996;55-63.
15. Ignatowski T.A., Noble B.K., Wright J.R., Gorfien J.L., Heffner R.R., Spengler R.N. Neuronal-associated tumor necrosis factor (TNFα): its role in noradrenergic functioning and modification of its expression following antidepressant drug administration. J. Neuroimmunol. 79:1997;84-90.
16. Ignatowski T.A., Covey W.C., Knight P.R., Severin C.M., Nickola T.J., Spengler R.N. Brain-derived TNFα mediates neuropathic pain. Brain Res. 841:1999;70-77.
17. 2-adrenergic and prostaglandin response in the regulation of macrophage-derived tumor necrosis factor. Clin. Immunol. 96(1):2000;44-51.
18. Maier S.F., Watkins L.R. Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition. Psychol. Rev. 105:1998;83-107.
19. Nader N.D., Ignatowski T.A., Kurek C.J., Knight P.R., Spengler R.N. Clonidine suppresses plasma and cerebrospinal fluid concentrations of TNF-alpha during the perioperative period. Anesth. Analg. 93(2):2001;363-369.
20. 2-adrenergic sensitivity and levels of TNF in the rat brain. J. Neuroimmunol. 107:2000;50-58.
21. 2C-adrenoceptors in human neuroblastoma SH-SY5Y cells. Eur. J. Pharmacol. 372:1999;109-115.
22. Reithmann C., Gierschik P., Jakobs K.H., Werdan K. Regulation of adenylyl cyclase by noradrenaline and tumor necrosis factor α in rat cardiomyocytes. Eur. Heart J. 12(Suppl. F):1991;139-142.
23. Remold-O'Donnell E. Stimulation and desensitization of macrophage adenylate cyclase by prostaglandins and catecholamines. J. Biol. Chem. 249:1974;3615-3621.
24. 2- adrenergic receptor activation. J. Neurosci. Res. 67:2002;264-274.
25. Rock C.S., Lowry S.F. Current research reviews: tumor necrosis factor-α J. Surg. Res. 51:1991;434-445.
26. Scherzer J.A., Lin Y., McLeish K.R., Klein J.B. TNF translationally modulates the expression of G1 protein alpha(i2) subunits in human polymorphonuclear leukocytes. J. Immunol. 158(2):1997;913-918.
27. 3H]norepinephrine release by activation of alpha-2 adrenergic receptors in cultured rat ganglion cells. Neuroscience. 52:1993;107-113.
28. 2- Adrenoreceptors in rat brain are decreased after long-term tricyclic antidepressant drug treatment. Brain Res. 210:1981;413-418.
29. 2-mediated suppression of lipopolysaccharide-induced tumor necrosis factor alpha gene expression. Infect. Immun. 57(9):1989;2837-2841.
30. 2-induced suppression. J. Immunol. 142(12):1989;4346-4350.
31. Spengler R.N., Allen R.M., Remick D.G., Strieter R.M., Kunkel S.L. Stimulation of α-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor. J. Immunol. 145(5):1990;1430-1434.
32. Spengler R.N., Chensue S.W., Giacherio D.A., Blenk N., Kunkel S.L. Endogenous norepinephrine regulates tumor necrosis factor-α production from macrophages in vitro. J. Immunol. 152:1994;3024-3031.
33. Starke K. Regulation of noradrenaline release by presynaptic receptor systems. Rev. Physiol., Biochem. Pharmacol. 77:1977;1-124.
34. Stoll G., Jander S., Schroeter M. Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system. Adv. Exp. Med. Biol. 513:2002;87-113.
35. 2. Int. J. Immunopharmacol. 17:1995;779-786.