Mechanisms responsible for the in vitro relaxation of a novel dibenzothiepine derivative (NSU-242) on tracheal and vascular smooth muscles

European Journal of Pharmacology

Volumn 488, Issue 1-3, 2004, Pages 191-199

  Ozaki, Hiroshi ^a   Hori, Masatoshi ^a   Takeo, Jiro ^b   Hata, Jun Ichiro ^b   Jinno, Shuji ^b   Okita, Takaaki ^b   Yamashita, Shinya ^b   Karaki, Hideaki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NIPPON SUISAN KAISHA LTD   (Japan)

Author keywords

Actin assembly; Myosin phosphorylation; NSU 242; Relaxation; Tracheal smooth muscle

Indexed keywords

ACTIN; CALCIUM; CARBACHOL; CYCLIC AMP; CYCLIC GMP; CYTOCHALASIN D; DIBENZOTHIEPIN DERIVATIVE; FLUORESCEIN ISOTHIOCYANATE; MYOSIN LIGHT CHAIN; NORADRENALIN; NSU 242; POTASSIUM; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; GUINEA PIG; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; STAINING; STRESS FIBER; TRACHEA MUSCLE; VASCULAR SMOOTH MUSCLE;

ACTOMYOSIN; ANIMALS; BRONCHOCONSTRICTION; CARBACHOL; CYCLIC AMP; CYCLIC GMP; DIBENZOTHIEPINS; GUINEA PIGS; MICROFILAMENTS; MUSCARINIC AGONISTS; MUSCLE RELAXATION; MUSCLE, SMOOTH; MUSCLE, SMOOTH, VASCULAR; MYOSIN LIGHT CHAINS; PHOSPHORYLATION; POTASSIUM CHLORIDE; SWINE; TRACHEA;

EID: 1642293182     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.02.017     Document Type: Article

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