Vertex inhibitors of Aurora-2, glycogen synthase kinase-3 and Src kinase

Expert Opinion on Therapeutic Patents

Volumn 14, Issue 3, 2004, Pages 439-443

[No Author Info available]

Author keywords

Aurora 2; Glycogen synthase kinase 3 (GSK 3); Kinase inhibitor; Quinazoline; Src; Vertex

Indexed keywords

2 METHYLSULFONE DERIVATIVE 9; ENZYME INHIBITOR; FUSED HETEROCYCLIC RINGS; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; HUMAN; PATENT; PUBLISHING; STRUCTURE ACTIVITY RELATION;

EID: 1642283587     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/eotp.14.3.439.27472     Document Type: Article

References (1)

1. FOX T, COLL JT, XIE X et al.: A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase. Protein Sci. (1998) 7:2249-2255.