Histamine-stimulated nerve growth factor secretion from cultured astrocyctes is blocked by protein kinase C inhibitors

Inflammation Research

Volumn 53, Issue SUPPL. 1, 2004, Pages

  Lipnik Stangelj M ^a   Carman Krzan M ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ADENYLATE CYCLASE; CALCIUM ION; DIACYLGLYCEROL; HISTAMINE; HISTAMINE H1 RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PROTEIN KINASE C INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ASTROCYTE; CELL CULTURE; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; HORMONE RELEASE; NONHUMAN; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ASTROCYTES; CELLS, CULTURED; ENZYME INHIBITORS; HISTAMINE; MAP KINASE SIGNALING SYSTEM; NERVE GROWTH FACTOR; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; RATS; RATS, WISTAR;

EID: 1642280381     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00011-003-0327-0     Document Type: Conference Paper

References (8)

1. Čarman-Kržan M, Wise BC. Arachidonic acid lipoxygenation may mediate interleukin-1 stimulation of nerve growth factor secretion in astroglial cultures. J Neurosci Res 1993; 34: 225-32.
2. Jehan F, Neveu I, Naveilhan P, Wion D, Brachet P. Interactions between second messenger pathways influence NGF synthesis in mouse primary astrocytes. Brain Res 1995; 672: 128-36.
3. Lipnik-Štangelj M, Jurič DM, Čarman-Kržan M. Histamine-induced synthesis and secretion of nerve growth factor from astrocytes. Inflamm Res 1998; 47(Suppl 1): S34-5.
4. 3-receptor antagonists on histamine stimulated NGF release from cultured astrocytes. Inflamm Res 2001; 50 (2): S84-5.
5. Obara Y, Kobayashi H, Ohta T, Ohizumi Y, Nakahata N. Scabronine G-Methylester Enhances secretion of neurotrophic factors mediated by an activation of protein kinase C-ζ. Mol Pharmacol 2001; 59: 1287-97.
6. 1-receptor to the nucleus. Mol Pharmacol 2001; 59: 1012-21.
7. Čarman-Kržan M, Vige X, Wise BC. Regulation by interleukin-1 of nerve growth factor secretion and nerve growth factor mRNA expression in rat primary astroglial cultures. J Neurochem 1991; 56(2): 636-43.
8. Korsching S, Thoenen H. Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation. Proc Natl Acad Sci USA 1983; 80: 3513-6.