Folding and binding integrity of variants of a prototype ligand-binding module from the LDL receptor possessing multiple alanine substitutions

Biochemistry

Volumn 44, Issue 13, 2005, Pages 5075-5085

  Abdul Aziz, Dunia ^a   Fisher, Carl ^a   Beglova, Natalia ^a   Blacklow, Stephen C ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CELLS; HYDROGEN BONDS; ISOMERS; NITROGEN COMPOUNDS;

LIGANDS; NONREDUNDANT PROTEIN SEQUENCE;

BIOCHEMISTRY;

ALANINE; APOLIPOPROTEIN E; CALCIUM; CYSTEINE; DISULFIDE; LOW DENSITY LIPOPROTEIN RECEPTOR;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; ISOMER; LIGAND BINDING; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; PROTEIN VARIANT;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; APOLIPOPROTEINS E; BINDING SITES; CALCIUM; DIMYRISTOYLPHOSPHATIDYLCHOLINE; HUMANS; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, LDL; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; VARIATION (GENETICS);

EID: 16344394980     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047575j     Document Type: Article

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