Initiation of highly active antiretroviral therapy in advanced AIDS with CD4<50 cells/mm3 in a resource-limited setting: Efficacy and tolerability

International Journal of STD and AIDS

Volumn 16, Issue 3, 2005, Pages 243-246

  Sungkanuparph, Somnuek ^a   Kiertiburanakul, Sasisopin ^a   Manosuthi, Weerawat ^a   Kiatatchasai, Wiphawee ^a   Vibhagool, Asda ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Advanced AIDS; Antiretroviral therapy; Efficacy; HIV; Resource limited setting

Indexed keywords

ABACAVIR; ANTIRETROVIRUS AGENT; EFAVIRENZ; INDINAVIR; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; AGED; ANEMIA; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DEVELOPING COUNTRY; DIZZINESS; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FEVER; FOLLOW UP; FUNGAL MENINGITIS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV ASSOCIATED LIPODYSTROPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NAUSEA; OPPORTUNISTIC INFECTION; PANCREATITIS; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; RASH; RETROSPECTIVE STUDY; STEVENS JOHNSON SYNDROME; THAILAND; TUBERCULOSIS; VOMITING;

ADULT; AGED; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; MIDDLE AGED; POVERTY; RETROSPECTIVE STUDIES; RNA, VIRAL; TREATMENT OUTCOME;

EID: 16344393524     PISSN: 09564624     EISSN: None     Source Type: Journal    
DOI: 10.1258/0956462053420121     Document Type: Article

References (25)

1. Egger M, Hirschel B, Francioli P, et al. Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study: Swiss HIV Cohort Study. BMJ 1997;315:1194-9
2. Mocroft A, Vella S, Benfield T, et al. Changing patterns of mortality across Europe in patients infected with HIV-1. Lancet 1998;352:1725-30
3. Palella Jr FJ, Delaney KM, Moorman AC, et al., HIV Outpatient Study Investigators. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998;338:853-60
4. Egger M, May M, Chene G, et al. Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies. Lancet 2002;360:119-29
5. Sathapatayavongs B, Thakkinstian A, Promchanyakul K. Five-year experience on AIDS 1990-1994: Ramathibodi Hospital, Thailand. J Infect Dis Antimicrob Agents 1999;16:69-72
6. Ruxrungtham K, Phanuphak P. Update on HIV/AIDS in Thailand. J Med Assoc Thai 2001;84(Suppl 1):S1-7
7. Fisk DT, Meshnick S, Kazanjian PH. Pneumocystis carinii pneumonia in patients in the developing world who have acquired immunodeficiency syndrome. Clin Infect Dis 2003;36:70-8
8. Cameron DW. Needs and prospects for HIV therapy in developing countries. J Int Assoc Physicians AIDS Care 2002;1:44-5
9. Dorrington R, Bradshaw D, Budlender D, Bourne D. The current state and future projections of the HIV/AIDS epidemic in South Africa. SADJ 2002;57:449-50
10. Sachs J. HIV/AIDS in developing countries. J R Soc Med 2002;95:631-2
11. Staszewski S, Morales-Ramirez J, Tashima KT, et al. Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults. Study 006 Team. N Engl J Med 1999;341:1865-73
12. Shafer RW, Smeaton LM, Robbins GK, et al. AIDS Clinical Trials Group 384 Team. Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med 2003;349:2304-15
13. Robbins GK, De Gruttola V, Shafer RW, et al. AIDS Clinical Trials Group 384 Team. Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med 2003;349:2293-303
14. Keiser P, Nassar N, Yazdani B, Armas L, Moreno S. Comparison of efficacy of efavirenz and nevirapine: lessons learned for cohort analysis in light of the 2NN Study. HIV Clin Trials 2003;4:358-60
15. Shelburne III SA, Hamill RJ, Rodriguez-Barradas MC, et al. Immune reconstitution inflammatory syndrome: emergence of a unique syndrome during highly active antiretroviral therapy. Medicine (Baltimore) 2002;81:213-27
16. Behrens GM, Meyer D, Stoll M, Schmidt RE. Immune reconstitution syndromes in human immuno-deficiency virus infection following effective antiretroviral therapy. Immunobiology 2000;202:186-93
17. Sungkanuparph S, Vibhagool A, Mootsikapun P, Chetchotisakd P, Tansuphaswaswadikul S, Bowonwatanuwong C. Opportunistic infections after the initiation of highly active antiretroviral therapy in advanced AIDS patients in an area with a high prevalence of tuberculosis. AIDS 2003;17: 2129-31
18. Jenny-Avital ER, Abadi M. Immune reconstitution cryptococcosis after initiation of successful highly active antiretroviral therapy. Clin Infect Dis 2002;35:e128-33
19. King MD, Perlino CA, Cinnamon J, Jernigan JA. Paradoxical recurrent meningitis following therapy of cryptococcal meningitis: an immune reconstitution syndrome after initiation of highly active antiretroviral therapy. Int J STD AIDS 2002;13:724-6
20. Hoffmann C, Horst HA, Albrecht H, Schlote W. Progressive multifocal leucoencephalopathy with unusual inflammatory response during antiretroviral treatment. J Neurol Neurosurg Psychiatry 2003;74:1142-4
21. Cinque P, Pierotti C, Vigano MG, et al. The good and evil of HAART in HIV-related progressive multifocal leukoencephalopathy. J Neurovirol 2001;7:358-63
22. van Leeuwen R, Katlama C, Murphy RL, et al. A randomized trial to study first-line combination therapy with or without a protease inhibitor in HIV-1-infected patients. AIDS 2003;17:987-99
23. Erb P, Battegay M, Zimmerli W, Rickenbach M, Egger M. Effect of antiretroviral therapy on viral load, CD4 cell count, and progression to acquired immunodeficiency syndrome in a community human immunodeficiency virus-infected cohort. Swiss HIV Cohort Study. Arch Intern Med 2000;160:1134-40
24. Landon BE, Wilson IB, Cohn SE, et al. Physician specialization and antiretroviral therapy for HIV. J Gen Intern Med 2003;18:233-41
25. Laine C, Markson LE, McKee LJ, Hauck WW, Fanning TR, Turner BJ. The relationship of clinic experience with advanced HIV and survival of women with AIDS. AIDS 1998;12:417-24