Plasma glutamine changes after high-intensity exercise in elite male swimmers

Research in Sports Medicine

Volumn 13, Issue 1, 2005, Pages 7-21

  Kargotich, Stephen ^a   Rowbottom, David G ^a   Keast, David ^a   Goodman, Carmél ^a   Dawson, Brian ^a   Morton, Alan R ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Diurnal cycle; Diurnal exercise; Glutamine; Swimming

Indexed keywords

GLUTAMINE;

ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; CIRCADIAN RHYTHM; CONTROLLED STUDY; EXERCISE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; SWIMMING; TRAINING; VENOUS BLOOD;

ADULT; EXERTION; GLUTAMINE; HEART RATE; HUMANS; LACTIC ACID; MALE; SWIMMING;

EID: 16344386009     PISSN: 15438627     EISSN: None     Source Type: Journal    
DOI: 10.1080/15438620590922040     Document Type: Article

References (36)

1. Ardawi MSM, Newsholme EA (1985) Metabolism in lymphocytes and its importance in the immune response. Essays in Biochemistry 21: 1-44.
2. Brand K, Leibold W, Luppa P, Schoener C, Schultz A (1986) Metabolic alterations associated with proliferation of mitogen activated lymphocytes and of lymphoblastoid cell lines: evaluation of glucose and glutamine metabolism. Immunology 173: 23-34.
3. Calder P, Newsholme EA (1991) Glutamine promotes interleukin-2 production by concanavalin A-stimulated lymphocytes. Proceedings of Nutrition Society 51: 105A.
4. Castell LM (2003) Glutamine supplementation in vitro and in vivo, in exercise and in immunosuppresion. Sports Medicine 33(5): 323-345.
5. Castell LM, Liu CT, Newsholme EA (1995) Diurnal variation of plasma glutamine and arginine in normal and fasting subjects. Proceedings of Nutrition Society 54: 118A.
6. Castell LM, Newsholme EA (2001) The relation between glutamine and the immunodepression observed in exercise. Amino Acids 20: 49-61.
7. Decömbaz J, Reinhardt P, Anantharaman K, Von Glutz G, Poortmans J (1979) Biochemical changes in a 100km run: Free amino acids, urea, and creatinine. European Journal of Applied Physiology 41: 61-72.
8. Dill DB, Costill DL (1974) Calculation of percentage changes in volumes of red blood cells and plasma in dehydration. Journal of Applied Physiology 37: 247-248.
9. Feigin RD, Klainer AS, Beisel WR (1967) Circadian periodicity of blood amino acids in adult men. Nature 215: 512-514.
10. Feigin RD, Klainer AS, and Beisel WR (1968) Factors affecting circadian periodicity of blood amino acids in man. Metabolism 17: 764-775.
11. Frisina JP, Gaudieri S, Cable T, Keast D, Palmer T (1994) Effects of acute exercise on lymphocyte subsets and metabolic activity. International Journal of Sports Medicine 15: 36-41.
12. Fry RW, Morton AR, Crawford GPM, Keast D (1992) Cell numbers and in vitro responses of leucocytes and lymphocyte subpopulations following maximal exercise and interval training sessions of different intensities. European Journal of Applied Physiology 64: 218-227.
13. Greig JE, Rowbottom DG, Keast D (1995) The effect of a common (viral) stress on plasma glutamine concentrations. Medical Journal of Australia 163: 385-388.
14. Griffiths M, Keast D (1990) The effect of glutamine on marine splenic leukocyte responses to T and B cell mitogens. Immunology and Cell Biology 68: 405-408.
15. Halson SL, Lancaster GI, Jeukendrup AE, Gleeson M (2003) Immunological responses to overreaching in cyclists. Medicine and Science in Sports and Exercise 35(5): 854-861.
16. Kargotich S, Keast D, Goodman C, Rowbottom D, Morton A (1997a) The influence of exercise induced plasma volume changes on the interpretation of biochemical data following high intensity exercise. Clinical Journal of Sports Medicine 7(3): 185-191.
17. Kargotich S, Keast D, Goodman C, Crawford G, Morton A (1997b). The influence of blood volume changes on leucocyte and lymphocyte subpopulations in elite swimmers following interval training of varying intensities. International Journal of Sports Medicine 18(5): 373-338.
18. Katz A, Broberg S, Sahlin K, Wahren J (1986) Muscle ammonia and amino acid metabolism during dynamic exercise in man. Clinical Physiology 6: 365-379.
19. Keast D, Arstein D, Harper W, Fry R, Morton A (1995) Depression of plasma glutamine following exercise stress and its possible influence on the immune system. Medical Journal of Australia 162: 15-18.
20. Keast D, Harper W, Rowbottom DG, Greig S, Kargotich S (1998) A simple bacterial bioassay for the measurement of L-glutamine. Annals of Clinical Biochemistry 35(1): 110-114.
21. Newsholme EA, Lang J, Relamn AS (1982) Control of rate of glutamine metabolism in the kidney. Contributions to Nephrology 31: 1-4.
22. Newsholme EA, Parry-Billings M (1990) Properties of glutamine release from muscle and its importance in the immune system. Journal of Parenteric and Enteric Nutrition 14: 635-675.
23. Nieman DC, Miller AR, Henson DA, Warren G, Gusewitch G, Johnson R, Davis J, Butterworth D, Herring J, Nehlsen-Cannarella S (1994). Effects of high-versus moderate-intensity exercise on lymphocyte subpopulations and proliferative response. International Journal of Sports Medicine 15: 199-206.
24. Parry-Billings M, Budgett R, Koutedakis Y, Williams C, Calder P, Pilling S, Baigrie R, Newsholme EA (1992) Plasma amino acid concentrations in the overtraining syndrome: possible effects on the immune system. Medicine and Science in Sports and Exercise 24: 1353-1358.
25. Pyne DB (1994) Exercise-induced muscle damage and inflammation: A review. Australian Journal of Science and Medicine in Sport 26: 49-58.
26. Rhode T, MacLean DA, Hartkopp A (1996) The immune system and serum glutamine during a triathlon. European Journal of Applied Physiology 74: 428-434.
27. Rowbottom DG, Keast D, Goodman C, Morton A (1995) The haematological, biochemical and immunological profile of athletes suffering from the overtraining syndrome. European Journal of Applied Physiology 70: 502-509.
28. Rowbottom DG, Keast D, Morton AR (1996) The emerging role for glutamine as an indicator of exercise stress and overtraining. Sports Medicine 21: 80-97.
29. Schneider YJ, Lavoix A (1990) Monoclonal antibody production in semicontinuous serum- and protein-free culture. Journal of Immunology Methods 129: 405-408.
30. Sewell DA, Gleeson M, Blannin AK (1994) Hyperammoneamia in relation to high-intensity exercise duration in man. European Journal of Applied Physiology 69: 350-354.
31. Smith LL (2000) Cytokine hypothesis of overtraining: A physiological adaptation to excessive stress. Medicine and Science in Sports and Exercise 32: 317-331.
32. Telford RD, Tumility D, Damm G (1984) Skinfold measurements in well performed Australian athletes. Sports Science and Medicine Quarterly 1: 13-16.
33. Wallace C, Keast D (1992) Glutamine and macrophage function. Metabolism 41: 1016-1020.
34. Walsh NP, Blanuin AK, Robson PJ, Gleeson M (1998) Glutamine, exercise and immune function: links and possible mechanisms. Sports Medicine 26: 177-191.
35. Welbourne TC, Childress D, Givens G (1986) Renal regulation of interorgan glutamine flow in metabolic acidosis. American Journal of Physiology 251: R858-R866.
36. Welbourne TC, Joshi S (1990) Interorgan glutamine metabolism during acidosis. Journal of Parenteric and Enteric Nutrition 14: S77-S85