Biochemical analysis and immunohistochemical determination of cardiac troponin for the postmortem diagnosis of myocardial damage

Histology and Histopathology

Volumn 20, Issue 2, 2005, Pages 475-481

  Martinez Diaz F ^a   Rodriguez Morlensin M ^a   Perez Carceles M D ^a   Noguera, J ^b   Luna, A ^a   Osuna, E ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

Author keywords

Damage; Myocardial; Postmortem

Indexed keywords

BIOTIN; CREATINE KINASE MB; EOSIN; FORMALDEHYDE; HEMATOXYLIN; MYOGLOBIN; PARAFFIN; PEROXIDASE; STREPTAVIDIN; TROPONIN; TROPONIN C; TROPONIN I; TROPONIN T;

ADOLESCENT; ADULT; AGED; ARTICLE; BIOCHEMISTRY; BLOOD SAMPLING; CADAVER; CAUSE OF DEATH; CHILD; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; HEART INFARCTION; HEART MUSCLE INJURY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; KRUSKAL WALLIS TEST; MALE; PERICARDIAL EFFUSION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ASPHYXIA; AUTOPSY; CAUSE OF DEATH; CHILD; DEATH, SUDDEN, CARDIAC; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MULTIPLE TRAUMA; MYOCARDIAL INFARCTION; MYOCARDIUM; TROPONIN C; TROPONIN T;

EID: 16344367371     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Adams J.E., Davila-Roman V.G., Bessey P.Q., Blake D.P., Ladenson J.H. and Jaffe A.S. (1996). Improved detection of cardiac contusion with cardiac troponin I. Am. Heart J. 131, 308-312.
2. Antman E.M., Sacks D.B., Rifai N., McCabe C.H., Cannon C.P. and Braunwald E. (1998). Time to positivity of a rapid bedside assay for cardiac-specific troponin T predicts prognosis in acute coronary syndromes: a Thrombolysis in myocardial infarction (TIMI) 11A substudy. J. Am. Coll. Cardiol. 31, 326-330.
3. Bertinchant J.P., Larue C., Pernel I., Ledermann B., Fabbro-Peray P., Beck L., Calzolari C., Trinquier S., Nigond J. and Pau B. (1996). Release kinetics of serum cardiac troponin I in ischemic myocardial injury. Clin. Biochem. 29, 587-594.
4. Bodor G.S., Proterfield D., Voss E.M., Smith S. and Apple F.S. (1995). Cardiac troponin is not expressed in fetal and healthy or diseased adult human skeletal muscle tissue. Clin. Chem. 41, 1710-1715.
5. Butany J. and Woo A. (2001). The pericardium and its diseases. In: Cardiovascular pathology. 3rd ed. Silver M.D., Gotlieb A.I. and Schoen F.J. (eds). Churchill Livingstone. Edimburgh. pp 375-401.
6. Cina S.J., Li D.J., Chan D.W., Boitnott J.K., Hruban R.H. and Smialek J.E. (1998). Serum concentrations of cardiac troponin I in sudden death. Am. J. Forensic Med. Pathol. 19, 324-328.
7. Cina S.J., Brown D.K., Smialek J.E. and Collins K.A. (2001). A rapid postmortem cardiac troponin T assay. Am. J. Forensic Med. Pathol. 22, 173-176.
8. Coe J.I. (1993) Postmortem chemistry update: emphasis on forensic application. Am. J. Forensic Med. Pathol. 14, 91-117.
9. Coudrey L. (1998). The troponins. Arch, Intern. Med. 158, 1173-1180.
10. Ebell M.H., Flewelling D. and Flynn C.A. (2000). A systematic review of troponin T and I for diagnosing acute myocardial infarction. J. Fam. Pract. 49, 550-556.
11. Fredericks S., Murray J.F., Bewick M., Chang R., Collison P.O., Carter N.D. and Holt D.W. (2001). Cardiac troponin T and creatine kinase MB are not increased in exterior oblique muscle of patients with renal failure. Clin. Chem. 47, 1023-1030.
12. Hansen S.H. and Rossen K. (1999). Evaluation of cardiac troponin I immunorection in autopsy hearts: a possible marker of early myocardial infarction. Forensic Sci. Int. 99, 189-196.
13. Heeschen C., Deu A., Langenbrink L., Goldmann B.U. and Hamm C.W. (2000). Analytical and diagnostic performance of troponin assays in patients suspicious for acute coronary syndromes. Clin. Biochem. 33, 359-368.
14. Hein S., Scheffold T. and Schaper J. (1995). Ischemia induces early changes to cytoskeletal and contractile protein in diseased human myocardium. J. Thorac. Cardiovasc. Surg. 110, 89-98.
15. Hsu S., Raine L. and Fanger H. (1981). Use of avidin-biotin-peroxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 29, 577-580.
16. Janssen W. (1984). Histological findings in poisoning. In: Forensic histopathology. Janssen W. (ed). Springer Verlag. Berlin. pp 293-328.
17. Katus H.A., Looser S., Hallermayer K., Remppis A., Scheffold T., Borgya A., Essig U. and Geuss U. (1992). Development and in vitro characterization of a new immunoassay of cardiac troponin. Clin. Chem. 38, 386-393.
18. Lachica E., Villanueva E. and Luna A. (1988). Comparison of different techniques for the postmortem diagnosis of myocardial infartion. Forensic Sci. Int. 38, 21-26.
19. Larue C., Calzolari C., Bertinchant J.P., Leclercq F., Grolleau R. and Pau B. (1993). Cardiac-specific immunoenzymometric assay of troponin I in the early phase of acute myocardial infarction. Clin. Chem. 39, 972-979.
20. Leadbetter S., Wawman H.M. and Jasani B. (1990). Further evaluation of immunocytochemical staining in the diagnosis of early myocardial ischaemic/hypoxic damage. Forensic Sci. Int. 45, 135-141.
21. Luna A., Villanueva E., Castellano M. and Jiménez G. (1982). The determination of CK, LDH and its isoenzymes in pericardial fluid and its application to the postmortem diagnosis of myocardial infarction. Forensic Sci. Int. 19, 85-91.
22. Mair J., Wagner I., Morass B., Fridich L., Lechleitner P., Dienstl F., Calzolari C., Larue C. and Puschendorf B. (1995). Cardiac troponin I release correlates with myocardial infarction size. Eur. J. Clin. Chem. Clin. Biochem. 33, 869-872.
23. Martinez-Diaz F., Bernal-Gilar M., Gomez-Zapata M. and Luna A. (2004). Expression and significance of cell immunohistochemical markers (HHF-35, CD-31, Bcl-2, P-53 and apopDETEC®) in hypertrophic cardiomyopathy. Histol. Histopathol. 19, 9-14.
24. Ognibene A., Mori F., Santoni R., Zuppiroli A., Peris A., Targioni G. and Dolara A. (1998). Cardiac troponin I in myocardial contusion. Clin. Chem. 44, 889-890.
25. Ortmann C., Pfeiffer H. and Brinkmann B. (2000). A comparative study on the immunohistochemical detection of early myocardial damage. Int. J. Legal Med. 113, 215-220.
26. Ortmann C., Pfeiffer H. and Brinkmann B. (2001). Immunohistochemical alterations after intravital and post-mortem trauamtic myocardial damage. Int. J. Legal Med. 115, 23-28.
27. Osuna E., Pérez Cárceles M.D., Álvarez M.V., Noguera. J. and Luna A. (1998a). Cardiac troponin I (cTnI) and the postmortem diagnosis of myocardial infarction. Int. J. Legal Med. 111, 173-176.
28. Osuna E., Pérez Cárceles M.D., Vieira D.N. and Luna A. (1998b). Distribution of biochemical markers in biological fluids. Application to the postmortem diagnosis of myocardial infarction. Am. J. Forensic Med. Pathol. 19, 123-128.
29. Pagani F., Bonetti G. and Panteghini M. (2001). Comparative study of cardiac troponin I and T measurements in a routine extracardiological clinical setting. J. Clin. Lab. Anal. 15, 210-214.
30. Pérez Cárceles M.D., Osuna E., Vieira D.N., Martínez A. and Luna A. (1995). Biochemical assesment of acute myocardial ischaemia. J. Clin. Pathol. 48, 124-128.
31. Pérez Cárceles M.D., Noguera J., Jiménez J.L., Martínez, P., Luna A. and Osuna E. (2004). Diagnostic efficacy of biochemical markers in diagnosis post-mortem of ischaemic heart disease. Forensic Sci. Int. 142, 1-7.
32. Stewart R.V., Zumwalt R.E., Hirsch C.S. and Kaplan L. (1984). Postmortem diagnosis of myocardial disease by enzymes assays of pericardial fluid. Am. J. Clin. Pathol. 82, 411-417.
33. Tenzer M.D. (1985). The spectrum of myocardial contusion: A review. J. Trauma 25, 620-627.