메뉴 건너뛰기




Volumn 13, Issue 3, 2005, Pages 153-159

Advances in opioid pharmacology

Author keywords

Metabolism; Opioids; Pharmacology; Receptors

Indexed keywords

ANALGESIC AGENT; BUPRENORPHINE; CODEINE; CYTOCHROME P450; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DIAMORPHINE; FENTANYL; HYDROMORPHONE; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; LEVORPHANOL; METHADONE; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALOXAZONE; NALOXONE; NORMORPHINE; NORPETHIDINE; OPIATE DERIVATIVE; OXYCODONE; PENTAZOCINE; PETHIDINE; RECEPTOR SUBTYPE; SEROTONIN UPTAKE INHIBITOR; SUFENTANIL; UNINDEXED DRUG;

EID: 16344367289     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-004-0690-6     Document Type: Review
Times cited : (32)

References (55)
  • 1
    • 0036323891 scopus 로고    scopus 로고
    • Clinical pharmacology of opioids for pain
    • Inturrisi CE (2002) Clinical pharmacology of opioids for pain. Clin J Pain 18:S3-13
    • (2002) Clin J Pain , vol.18
    • Inturrisi, C.E.1
  • 3
    • 0017138988 scopus 로고
    • Sigma effects of nalorphine in the chronic spinal dog
    • Gilbert PE, Martin WR (1976) Sigma effects of nalorphine in the chronic spinal dog. Drug Alcohol Depend 1:373-376
    • (1976) Drug Alcohol Depend , vol.1 , pp. 373-376
    • Gilbert, P.E.1    Martin, W.R.2
  • 4
    • 0017064976 scopus 로고
    • The effects of morphine- and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog
    • Martin WR, Eades CG, Thompson JA, Huppler RE, Gilbert PE (1976) The effects of morphine- and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog. J Pharmacol Exp Ther 197:517-532
    • (1976) J Pharmacol Exp Ther , vol.197 , pp. 517-532
    • Martin, W.R.1    Eades, C.G.2    Thompson, J.A.3    Huppler, R.E.4    Gilbert, P.E.5
  • 5
    • 0017735536 scopus 로고
    • Endogenous opioid peptides: Multiple agonists and receptors
    • Lord JA, Waterfield AA, Hughes J, Kosterlitz HW (1977) Endogenous opioid peptides: multiple agonists and receptors. Nature 267:495-499
    • (1977) Nature , vol.267 , pp. 495-499
    • Lord, J.A.1    Waterfield, A.A.2    Hughes, J.3    Kosterlitz, H.W.4
  • 6
    • 0019305614 scopus 로고
    • Multiple opiate receptors: [3H].ethylketocyclazocine receptor binding and ketocyclazocine analgesia
    • Pasternak GW (1980) Multiple opiate receptors: [3H].ethylketocyclazocine receptor binding and ketocyclazocine analgesia. Proc Natl Acad Sci USA 77:3691-3694
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 3691-3694
    • Pasternak, G.W.1
  • 7
    • 0027471855 scopus 로고
    • Pharmacological mechanisms of opioid analgesics
    • Pasternak GW (1993) Pharmacological mechanisms of opioid analgesics. Clin Neuropharmacol 16:1-18
    • (1993) Clin Neuropharmacol , vol.16 , pp. 1-18
    • Pasternak, G.W.1
  • 8
    • 12644300917 scopus 로고
    • Mediation of analgesia by multiple opioid receptors
    • Hill CS, Fields WS (eds) Raven Press, New York
    • Knapp RJ, Porreca F, Burks TF, Yamamura HI (1989) Mediation of analgesia by multiple opioid receptors. In: Hill CS, Fields WS (eds) Advances in pain research and therapy. Raven Press, New York, pp 247-289
    • (1989) Advances in Pain Research and Therapy , pp. 247-289
    • Knapp, R.J.1    Porreca, F.2    Burks, T.F.3    Yamamura, H.I.4
  • 10
    • 0011204773 scopus 로고
    • Classification of multiple morphine and enkephalin binding sites in the central nervous system
    • Wolozin BL, Pasternak GW (1981) Classification of multiple morphine and enkephalin binding sites in the central nervous system. Proc Natl Acad Sci U S A 78:6181-6185
    • (1981) Proc Natl Acad Sci U S A , vol.78 , pp. 6181-6185
    • Wolozin, B.L.1    Pasternak, G.W.2
  • 11
    • 0030469897 scopus 로고    scopus 로고
    • The u-opioid receptor
    • Traynor JR (1996) The u-opioid receptor. Pain Rev 3:221-248
    • (1996) Pain Rev , vol.3 , pp. 221-248
    • Traynor, J.R.1
  • 12
    • 0025770914 scopus 로고
    • Differential antagonism of opioid delta antinociception by [D-Ala2, Leu5, Cys6]. Enkephalin and naltrindole 5′-isothiocyanate: Evidence for delta receptor subtypes
    • Jiang Q, Takemori AE, Sultana M, Portoghese PS, Bowen WD, Mosberg HI, Porreca F (1991) Differential antagonism of opioid delta antinociception by [D-Ala2, Leu5, Cys6]. enkephalin and naltrindole 5′-isothiocyanate: evidence for delta receptor subtypes. J Pharmacol Exp Ther 257:1069-1075
    • (1991) J Pharmacol Exp Ther , vol.257 , pp. 1069-1075
    • Jiang, Q.1    Takemori, A.E.2    Sultana, M.3    Portoghese, P.S.4    Bowen, W.D.5    Mosberg, H.I.6    Porreca, F.7
  • 13
    • 0020364899 scopus 로고
    • Evidence for multiple "kappa" binding sites by use of opioid peptides in the guinea-pig lumbo-sacral spinal cord
    • Attali B, Gouarderes C, Mazarguil H, Audigier Y, Cros J (1982) Evidence for multiple "kappa" binding sites by use of opioid peptides in the guinea-pig lumbo-sacral spinal cord. Neuropeptides 3:53-64
    • (1982) Neuropeptides , vol.3 , pp. 53-64
    • Attali, B.1    Gouarderes, C.2    Mazarguil, H.3    Audigier, Y.4    Cros, J.5
  • 14
    • 0027202213 scopus 로고
    • Molecular cloning and functional expression of a mu-opioid receptor from rat brain
    • Chen Y, Mestek A, Liu J, Hurley JA, Yu L (1993) Molecular cloning and functional expression of a mu-opioid receptor from rat brain. Mol Pharmacol 44:8-12
    • (1993) Mol Pharmacol , vol.44 , pp. 8-12
    • Chen, Y.1    Mestek, A.2    Liu, J.3    Hurley, J.A.4    Yu, L.5
  • 17
    • 0036462450 scopus 로고    scopus 로고
    • Regulation of opioid receptor expression
    • Wei LN, Loh HH (2002) Regulation of opioid receptor expression. Curr Opin Pharmacol 2:69-75
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 69-75
    • Wei, L.N.1    Loh, H.H.2
  • 18
    • 16344371181 scopus 로고    scopus 로고
    • Clinical pharmacology of the treatment of chronic non-cancer pain
    • Giamberardino MA (ed) IASP Press, Seattle
    • Gourlay GK (2002) Clinical pharmacology of the treatment of chronic non-cancer pain. In: Giamberardino MA (ed) Pain 2002 - an updated review (refresher course syllabus). IASP Press, Seattle, pp 381-394
    • (2002) Pain 2002 - An Updated Review (Refresher Course Syllabus) , pp. 381-394
    • Gourlay, G.K.1
  • 19
    • 0036878162 scopus 로고    scopus 로고
    • Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method
    • Filizola M, Olmea O, Weinstein H (2002) Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method. Protein Eng 15:881-885
    • (2002) Protein Eng , vol.15 , pp. 881-885
    • Filizola, M.1    Olmea, O.2    Weinstein, H.3
  • 20
    • 0033578005 scopus 로고    scopus 로고
    • G-protein-coupled receptor heterodimerization modulates receptor function
    • Jordan BA, Devi LA (1999) G-protein-coupled receptor heterodimerization modulates receptor function. Nature 399:697-700
    • (1999) Nature , vol.399 , pp. 697-700
    • Jordan, B.A.1    Devi, L.A.2
  • 22
    • 0036551766 scopus 로고    scopus 로고
    • Opioid receptor genes inactivated in mice: The highlights
    • Gaveriaux-Ruff C, Kieffer BL (2002) Opioid receptor genes inactivated in mice: the highlights. Neuropeptides 36:62-71
    • (2002) Neuropeptides , vol.36 , pp. 62-71
    • Gaveriaux-Ruff, C.1    Kieffer, B.L.2
  • 28
    • 0032481350 scopus 로고    scopus 로고
    • Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50, 488H and attenuates morphine withdrawal
    • Simonin F, Valverde O, Smadja C, Slowe S, Kitchen I, Dierich A, Le Meur M, Roques BP, Maldonado R, Kieffer BL (1998) Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50, 488H and attenuates morphine withdrawal. EMBO J 17:886-897
    • (1998) EMBO J , vol.17 , pp. 886-897
    • Simonin, F.1    Valverde, O.2    Smadja, C.3    Slowe, S.4    Kitchen, I.5    Dierich, A.6    Le Meur, M.7    Roques, B.P.8    Maldonado, R.9    Kieffer, B.L.10
  • 30
    • 0034998004 scopus 로고    scopus 로고
    • The pharmacology of mu analgesics: From patients to genes
    • Pasternak GW (2001) The pharmacology of mu analgesics: from patients to genes. Neuroscientist 7:220-231
    • (2001) Neuroscientist , vol.7 , pp. 220-231
    • Pasternak, G.W.1
  • 31
    • 0036095186 scopus 로고    scopus 로고
    • Exploring the opioid system by gene knockout
    • Kieffer BL, Gaveriaux-Ruff C (2002) Exploring the opioid system by gene knockout. Prog Neurobiol 66:285-306
    • (2002) Prog Neurobiol , vol.66 , pp. 285-306
    • Kieffer, B.L.1    Gaveriaux-Ruff, C.2
  • 33
    • 0032436459 scopus 로고    scopus 로고
    • Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone
    • Heiskanen T, Olkkola KT, Kalso E (1998) Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. Clin Pharmacol Ther 64:603-611
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 603-611
    • Heiskanen, T.1    Olkkola, K.T.2    Kalso, E.3
  • 34
    • 0035876325 scopus 로고    scopus 로고
    • Hydromorphone-3-glucuronide: A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide
    • Wright AW, Mather LE, Smith MT (2001) Hydromorphone-3-glucuronide: a more potent neuro-excitant than its structural analogue, morphine-3-glucuronide. Life Sci 69:409-420
    • (2001) Life Sci , vol.69 , pp. 409-420
    • Wright, A.W.1    Mather, L.E.2    Smith, M.T.3
  • 35
    • 16344392053 scopus 로고    scopus 로고
    • Roxane Laboratories, Columbus, OH
    • Roxane Laboratories (2000) Levorphanol (prescribing information). Roxane Laboratories, Columbus, OH
    • (2000) Levorphanol (Prescribing Information)
  • 36
    • 0032903876 scopus 로고    scopus 로고
    • Methadone N-demethylation in human liver microsomes: Lack of stereoselectivity and involvement of CYP3A4
    • Foster DJ, Somogyi AA, Bochner F (1999) Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4. Br J Clin Pharmacol 47:403-412
    • (1999) Br J Clin Pharmacol , vol.47 , pp. 403-412
    • Foster, D.J.1    Somogyi, A.A.2    Bochner, F.3
  • 37
    • 0035433503 scopus 로고    scopus 로고
    • Pharmacologic management of acute and chronic pain: Focus on drug interactions and patient-specific pharmacotherapeutic selection
    • Barkin RL, Barkin D (2001) Pharmacologic management of acute and chronic pain: focus on drug interactions and patient-specific pharmacotherapeutic selection. South Med J 94:756-770
    • (2001) South Med J , vol.94 , pp. 756-770
    • Barkin, R.L.1    Barkin, D.2
  • 39
    • 0034053670 scopus 로고    scopus 로고
    • Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolites
    • Smith MT (2000) Neuroexcitatory effects of morphine and hydromorphone: evidence implicating the 3-glucuronide metabolites. Clin Exp Pharmacol Physiol 27:524-528
    • (2000) Clin Exp Pharmacol Physiol , vol.27 , pp. 524-528
    • Smith, M.T.1
  • 40
    • 0028981680 scopus 로고
    • The apparent affinity of morphine-3-glucuronide at mul-opioid receptors results from morphine contamination: Demonstration using HPLC and radioligand binding
    • Bartlett SE, Smith MT (1995) The apparent affinity of morphine-3-glucuronide at mul-opioid receptors results from morphine contamination: demonstration using HPLC and radioligand binding. Life Sci 57:609-615
    • (1995) Life Sci , vol.57 , pp. 609-615
    • Bartlett, S.E.1    Smith, M.T.2
  • 41
    • 0022532772 scopus 로고
    • Morphine intoxication in renal failure: The role of morphine-6- glucuronide
    • Osborne RJ, Joel SP, Slevin ML (1986) Morphine intoxication in renal failure: the role of morphine-6-glucuronide. BMJ 292:1548-1549
    • (1986) BMJ , vol.292 , pp. 1548-1549
    • Osborne, R.J.1    Joel, S.P.2    Slevin, M.L.3
  • 42
    • 0031746749 scopus 로고    scopus 로고
    • Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation
    • Eckhardt K, Li S, Ammon S, Schanzle G, Mikus G, Eichelbaum M (1998) Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation. Pain 76:27-33
    • (1998) Pain , vol.76 , pp. 27-33
    • Eckhardt, K.1    Li, S.2    Ammon, S.3    Schanzle, G.4    Mikus, G.5    Eichelbaum, M.6
  • 44
    • 0035221609 scopus 로고    scopus 로고
    • Meperidine - A liability
    • Waitman J, McCaffery M (2001) Meperidine - a liability. Am J Nurs 101:57-58
    • (2001) Am J Nurs , vol.101 , pp. 57-58
    • Waitman, J.1    McCaffery, M.2
  • 45
    • 2442766374 scopus 로고
    • Management of cancer pain, clinical guideline number 9
    • Agency for Healthcare Policy and Research (1994) Management of cancer pain, clinical guideline number 9 (AHCPR publication number 94-0592)
    • (1994) AHCPR Publication Number 94-0592
  • 46
    • 0021321306 scopus 로고
    • Effect of nonselective and selective inhibitors of monoamine oxidases A and B on pethidine toxicity in mice
    • Boden R, Botting R, Coulson P, Spanswick G (1984) Effect of nonselective and selective inhibitors of monoamine oxidases A and B on pethidine toxicity in mice. Br J Pharmacol 82:151-154
    • (1984) Br J Pharmacol , vol.82 , pp. 151-154
    • Boden, R.1    Botting, R.2    Coulson, P.3    Spanswick, G.4
  • 47
    • 0022616622 scopus 로고
    • Low doses of naloxone produce analgesia in the mouse brain by blocking presynaptic autoinhibition of enkephalin release
    • Ueda H, Fukushima N, Kitao T, Ge M, Takagi H (1986) Low doses of naloxone produce analgesia in the mouse brain by blocking presynaptic autoinhibition of enkephalin release. Neurosci Lett 65:247-252
    • (1986) Neurosci Lett , vol.65 , pp. 247-252
    • Ueda, H.1    Fukushima, N.2    Kitao, T.3    Ge, M.4    Takagi, H.5
  • 48
    • 0031033471 scopus 로고    scopus 로고
    • Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro
    • Vaughan CW, Christie MJ (1997) Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro. J Physiol 498 (Pt 2):463-472
    • (1997) J Physiol , vol.498 , Issue.2 PART , pp. 463-472
    • Vaughan, C.W.1    Christie, M.J.2
  • 49
    • 0035808569 scopus 로고    scopus 로고
    • Acute thermal hyperalgesia elicited by low-dose morphine in normal mice is blocked by ultra-low-dose naltrexone, unmasking potent opioid analgesia
    • Cram SM, Shen KF (2001) Acute thermal hyperalgesia elicited by low-dose morphine in normal mice is blocked by ultra-low-dose naltrexone, unmasking potent opioid analgesia. Brain Res 888:75-82
    • (2001) Brain Res , vol.888 , pp. 75-82
    • Cram, S.M.1    Shen, K.F.2
  • 50
    • 0028804902 scopus 로고
    • Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatment
    • Crain SM, Shen KF (1995) Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatment. Proc Natl Acad Sci U S A 92:10540-10544
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 10540-10544
    • Crain, S.M.1    Shen, K.F.2
  • 51
    • 0026506055 scopus 로고
    • The influence of naloxone infusion on the action of intrathecal diamorphine: Low-dose naloxone and neuroendocrine responses
    • Wright PM, O'Toole DP, Barron DW (1992) The influence of naloxone infusion on the action of intrathecal diamorphine: low-dose naloxone and neuroendocrine responses. Acta Anaesthesiol Scand 36:230-233
    • (1992) Acta Anaesthesiol Scand , vol.36 , pp. 230-233
    • Wright, P.M.1    O'Toole, D.P.2    Barron, D.W.3
  • 52
    • 0032925452 scopus 로고    scopus 로고
    • Effects of prophylactic nalmefene on the incidence of morphine-related side effects in patients receiving intravenous patient-controlled analgesia
    • Joshi GP, Duffy L, Chehade J, Wesevich J, Gajraj N, Johnson ER (1999) Effects of prophylactic nalmefene on the incidence of morphine-related side effects in patients receiving intravenous patient-controlled analgesia. Anesthesiology 90:1007-1011
    • (1999) Anesthesiology , vol.90 , pp. 1007-1011
    • Joshi, G.P.1    Duffy, L.2    Chehade, J.3    Wesevich, J.4    Gajraj, N.5    Johnson, E.R.6
  • 53
    • 0030730101 scopus 로고    scopus 로고
    • Opioid-sparing effects of a low-dose infusion of naloxone in patient-administered morphine sulfate
    • Gan TJ, Ginsberg B, Glass PS, Fortney J, Jhaveri R, Perno R (1997) Opioid-sparing effects of a low-dose infusion of naloxone in patient-administered morphine sulfate. Anesthesiology 87:1075-1081
    • (1997) Anesthesiology , vol.87 , pp. 1075-1081
    • Gan, T.J.1    Ginsberg, B.2    Glass, P.S.3    Fortney, J.4    Jhaveri, R.5    Perno, R.6
  • 54
    • 0036217546 scopus 로고    scopus 로고
    • The combination of low dose of naloxone and morphine in PCA does not decrease opioid requirements in the postoperative period
    • Cepeda MS, Africano JM, Manrique AM, Fragoso W, Carr DB (2002) The combination of low dose of naloxone and morphine in PCA does not decrease opioid requirements in the postoperative period. Pain 96:73-79
    • (2002) Pain , vol.96 , pp. 73-79
    • Cepeda, M.S.1    Africano, J.M.2    Manrique, A.M.3    Fragoso, W.4    Carr, D.B.5
  • 55
    • 0037219290 scopus 로고    scopus 로고
    • The combination of low dose of naloxone and morphine in patient-controlled (PCA) does not decrease opioid requirements in the postoperative period
    • Mehlisch DR (2003) The combination of low dose of naloxone and morphine in patient-controlled (PCA) does not decrease opioid requirements in the postoperative period. Pain 101:209-211
    • (2003) Pain , vol.101 , pp. 209-211
    • Mehlisch, D.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.