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Volumn 60, Issue 1, 2005, Pages 1-15

New approaches in pharmacology: Numerical modelling and simulation;Modélisation numérique et simulation: Nouvelles applications en pharmacologie

Author keywords

Drug development; Drug innovation; Numerical modelling; Simulation; Therapeutic models

Indexed keywords

BIOLOGICAL MODEL; CEREBROVASCULAR ACCIDENT; CLINICAL PHARMACOLOGY; DOSE RESPONSE; DRUG DEVELOPMENT; DRUG TOLERANCE; FRANCE; JAPAN; NEW ZEALAND; PHARMACOGENOMICS; PRIORITY JOURNAL; REVIEW; UNITED STATES;

EID: 16344363975     PISSN: 00405957     EISSN: None     Source Type: Journal    
DOI: 10.2515/therapie:2005001     Document Type: Article
Times cited : (4)

References (33)
  • 2
    • 85030796454 scopus 로고    scopus 로고
    • Complexité
    • Lecourt D, éditeur. Paris: Presse Universitaires de France (PUF)
    • Complexité. In: Lecourt D, éditeur. Dictionnaire d'histoire et philosophie des sciences. Paris: Presse Universitaires de France (PUF), 1999
    • (1999) Dictionnaire d'Histoire et Philosophie des Sciences
  • 3
    • 0033515888 scopus 로고    scopus 로고
    • Complexity in biological signaling systems
    • Wheng G, Bhalla US, Iyengar R. Complexity in biological signaling systems. Science 1999; 284: 92-6
    • (1999) Science , vol.284 , pp. 92-96
    • Wheng, G.1    Bhalla, U.S.2    Iyengar, R.3
  • 4
    • 0033764285 scopus 로고    scopus 로고
    • The challenge of in silica biology
    • Palsson B. The challenge of in silica biology. Nat Biotechnol 2000; 18: 1147-50
    • (2000) Nat Biotechnol , vol.18 , pp. 1147-1150
    • Palsson, B.1
  • 6
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: A brief overview
    • Kitano H. Systems biology: a brief overview. Science 2002; 295: 1662-4
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 7
    • 16344362951 scopus 로고    scopus 로고
    • Entretien avec François Jacob, propos recueillis par M Alberganti, H Morin, JY Nau. Avr 9
    • Entretien avec François Jacob, propos recueillis par M Alberganti, H Morin, JY Nau. Le Monde 2003 Avr 9; pp 25
    • (2003) Le Monde , pp. 25
  • 8
    • 0037177552 scopus 로고    scopus 로고
    • Schizophrenia: Diverse approaches to a complex disease
    • Sawa A, Snyder SH. Schizophrenia: diverse approaches to a complex disease. Science 2002; 296: 692-5
    • (2002) Science , vol.296 , pp. 692-695
    • Sawa, A.1    Snyder, S.H.2
  • 9
    • 0036499997 scopus 로고    scopus 로고
    • Modeling the heart: From genes to cells to the whole organ
    • Noble D. Modeling the heart: from genes to cells to the whole organ. Science 2002; 295: 1678-82
    • (2002) Science , vol.295 , pp. 1678-1682
    • Noble, D.1
  • 10
    • 0027750786 scopus 로고
    • A mathematical model for dynamics of cardiovascular drug action: Application to intravenous dihydropyridines in healthy volunteers
    • Francheteau P, Steimer JL, Merdjan H, et al. A mathematical model for dynamics of cardiovascular drug action: application to intravenous dihydropyridines in healthy volunteers. J Pharmacokinet Biopharm 1993; 21: 489-514
    • (1993) J Pharmacokinet Biopharm , vol.21 , pp. 489-514
    • Francheteau, P.1    Steimer, J.L.2    Merdjan, H.3
  • 11
    • 0031929690 scopus 로고    scopus 로고
    • Revisiting the effect compartment through timing errors in drug administration
    • Nony P, Cucherat M, Boissel JP. Revisiting the effect compartment through timing errors in drug administration. Trends Pharmacol Sci 1998; 19: 49-54
    • (1998) Trends Pharmacol Sci , vol.19 , pp. 49-54
    • Nony, P.1    Cucherat, M.2    Boissel, J.P.3
  • 12
    • 0036704883 scopus 로고    scopus 로고
    • Clinical trial simulation using therapeutic effect modelling: Application to ivabradine efficacy in patients with angina pectoris
    • Chabaud S, Girard P, Nony P, et al. Clinical trial simulation using therapeutic effect modelling: application to ivabradine efficacy in patients with angina pectoris. J Pharmacokinet Pharmacodyn 2002; 29: 339-63
    • (2002) J Pharmacokinet Pharmacodyn , vol.29 , pp. 339-363
    • Chabaud, S.1    Girard, P.2    Nony, P.3
  • 13
    • 0036296318 scopus 로고    scopus 로고
    • Use of sensitivity functions to characterise and compare the forgiveness of drugs
    • Nony P, Boissel JP. Use of sensitivity functions to characterise and compare the forgiveness of drugs. Clin Pharmacokinet 2002; 41: 371-80
    • (2002) Clin Pharmacokinet , vol.41 , pp. 371-380
    • Nony, P.1    Boissel, J.P.2
  • 14
    • 0036329408 scopus 로고    scopus 로고
    • Physiologically based model of acute ischemic stroke
    • Duval V, Chabaud S, Girard P, et al. Physiologically based model of acute ischemic stroke. J Cereb Blood Flow Metab 2002; 8: 1010-8
    • (2002) J Cereb Blood Flow Metab , vol.8 , pp. 1010-1018
    • Duval, V.1    Chabaud, S.2    Girard, P.3
  • 15
    • 0003331185 scopus 로고    scopus 로고
    • 'In silica' simulation of biological processes
    • Chichester: John Wiley & Sons
    • Bock G, Goode JA. editors. 'In silica' simulation of biological processes. Novartis Foundation Symposium 247. Chichester: John Wiley & Sons, 2002
    • (2002) Novartis Foundation Symposium 247
    • Bock, G.1    Goode, J.A.2
  • 17
    • 0035478586 scopus 로고    scopus 로고
    • The virtual-cell: A software environment for computational cell biology
    • Loew LM, Schaff JC. The virtual-cell: a software environment for computational cell biology. Trends Biotechnol 2001; 19: 401-6
    • (2001) Trends Biotechnol , vol.19 , pp. 401-406
    • Loew, L.M.1    Schaff, J.C.2
  • 18
    • 0033031386 scopus 로고    scopus 로고
    • E-cell: Software environment for whole cell simulation
    • Tomita M, Hashimoto K, Takahashi K, et al. E-cell: software environment for whole cell simulation. Bioinformatics 1999; 15: 72-84
    • (1999) Bioinformatics , vol.15 , pp. 72-84
    • Tomita, M.1    Hashimoto, K.2    Takahashi, K.3
  • 19
    • 0032783433 scopus 로고    scopus 로고
    • Biological simulations in drug discovery
    • Noble D, Levin J, Scott W. Biological simulations in drug discovery. Drug Discov Today 1999; 4: 10-6
    • (1999) Drug Discov Today , vol.4 , pp. 10-16
    • Noble, D.1    Levin, J.2    Scott, W.3
  • 20
    • 0019047847 scopus 로고
    • Multistage model for carcinogenesis
    • Moolgavkar S. Multistage model for carcinogenesis. J Natl Cancer Inst 1980; 65: 215-6
    • (1980) J Natl Cancer Inst , vol.65 , pp. 215-216
    • Moolgavkar, S.1
  • 21
    • 0032612371 scopus 로고    scopus 로고
    • Mechanisms of carcinogenesis and biologically based models for estimation and prediction of risk
    • Moolgavkar S, Krewski D, Schwarz M. Mechanisms of carcinogenesis and biologically based models for estimation and prediction of risk. IARC Sci Publ 1999; 131: 179-237
    • (1999) IARC Sci Publ , vol.131 , pp. 179-237
    • Moolgavkar, S.1    Krewski, D.2    Schwarz, M.3
  • 22
    • 0027853051 scopus 로고
    • Using cell replication data in mathematical modeling in carcinogenesis
    • Portier CJ, Kopp-Schneider A, Sherman CD. Using cell replication data in mathematical modeling in carcinogenesis. Environ Health Perspect. 1993; 101 Suppl. 5: 79-86
    • (1993) Environ Health Perspect , vol.101 , Issue.SUPPL. 5 , pp. 79-86
    • Portier, C.J.1    Kopp-Schneider, A.2    Sherman, C.D.3
  • 23
    • 13244297069 scopus 로고    scopus 로고
    • A mathematical model of doxorubicin treatment efficacy on non-Hodgkin's lymphoma: Investigation of current protocol through theoretical modelling result
    • Ribba B, Alarcon T, Marron K, et al. A mathematical model of doxorubicin treatment efficacy on non-Hodgkin's lymphoma: investigation of current protocol through theoretical modelling result. Bull Math Biol 2005; 67 (1): 79-99
    • (2005) Bull Math Biol , vol.67 , Issue.1 , pp. 79-99
    • Ribba, B.1    Alarcon, T.2    Marron, K.3
  • 24
    • 0034119297 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic modeling in drug development
    • Sheiner LB, Steimer JL. Pharmacokinetic/pharmacodynamic modeling in drug development. Annu Rev Pharmacol Toxicol 2000; 40: 67-95
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 67-95
    • Sheiner, L.B.1    Steimer, J.L.2
  • 25
    • 20244376293 scopus 로고    scopus 로고
    • Exploring the systems of life
    • Service RF. Exploring the systems of life. Science 1999; 284: 80-3
    • (1999) Science , vol.284 , pp. 80-83
    • Service, R.F.1
  • 26
    • 0034741193 scopus 로고    scopus 로고
    • Biomarqueurs biologiques: Utilisation pour le développement et l'approbation des médicaments
    • Gueyffier F, Dib M, Boissel JP. Biomarqueurs biologiques: utilisation pour le développement et l'approbation des médicaments. Therapie 2001; 56: 355-61
    • (2001) Therapie , vol.56 , pp. 355-361
    • Gueyffier, F.1    Dib, M.2    Boissel, J.P.3
  • 27
    • 7544241929 scopus 로고    scopus 로고
    • Simulation des essais cliniques dans le développement des médicaments
    • Girard P, Cucherat M, Guez D. Simulation des essais cliniques dans le développement des médicaments. Therapie 2004; 59: 287-95
    • (2004) Therapie , vol.59 , pp. 287-295
    • Girard, P.1    Cucherat, M.2    Guez, D.3
  • 28
    • 0034109599 scopus 로고    scopus 로고
    • A pharmacokinetic simulation model for ivabradine in healthy volunteers
    • Duffull SB, Chabaud S, Nony P, et al. A pharmacokinetic simulation model for ivabradine in healthy volunteers. Eur J Pharm Sc 2000; 10: 285-94
    • (2000) Eur J Pharm Sc , vol.10 , pp. 285-294
    • Duffull, S.B.1    Chabaud, S.2    Nony, P.3
  • 29
    • 0033175670 scopus 로고    scopus 로고
    • Intérêt pronostique de la mesure ambulatoire de pression artérielle en France
    • Gueyffier F, Cornu C, Bossard N, et al. Intérêt pronostique de la mesure ambulatoire de pression artérielle en France. Arch Mal Coeur Vaiss 1999; 92: 1151-5
    • (1999) Arch Mal Coeur Vaiss , vol.92 , pp. 1151-1155
    • Gueyffier, F.1    Cornu, C.2    Bossard, N.3
  • 30
    • 7744229387 scopus 로고    scopus 로고
    • Mathematical modelling of ischémic stroke: An integrative approach
    • Dronne MA, Boissel JP, Grenier E, et al. Mathematical modelling of ischémic stroke: an integrative approach. Acta Biotheoretica 2004; 52: 255-72
    • (2004) Acta Biotheoretica , vol.52 , pp. 255-272
    • Dronne, M.A.1    Boissel, J.P.2    Grenier, E.3
  • 31
    • 0030965063 scopus 로고    scopus 로고
    • Effect of antihypertensive drug treatment on cardiovascular outcomes in women and men: A meta-analysis of individual patient data from randomized, controlled trials
    • The INDANA (INdividual Data ANalysis of Antihypertensive intervention trials) Project Collaborators
    • Gueyffier F, Boutitie F, Boissel JP, et al. The INDANA (INdividual Data ANalysis of Antihypertensive intervention trials) Project Collaborators. Effect of antihypertensive drug treatment on cardiovascular outcomes in women and men: a meta-analysis of individual patient data from randomized, controlled trials. Ann Intern Med 1997; 126: 761-7
    • (1997) Ann Intern Med , vol.126 , pp. 761-767
    • Gueyffier, F.1    Boutitie, F.2    Boissel, J.P.3
  • 32
    • 0142106330 scopus 로고    scopus 로고
    • Absolute benefit, number needed to treat and gain in life expectancy: Which efficacy indices for measuring the treatment benefit?
    • Kassai B, Gueyffier F, Boissel JP, et al. Absolute benefit, number needed to treat and gain in life expectancy: which efficacy indices for measuring the treatment benefit? J Clin Epidemiol 2003; 56: 977-82
    • (2003) J Clin Epidemiol , vol.56 , pp. 977-982
    • Kassai, B.1    Gueyffier, F.2    Boissel, J.P.3
  • 33
    • 0032619603 scopus 로고    scopus 로고
    • Note sur l'épistémiologie de la pharmacologie clinique: Confrontation à l'approche de Karl Popper
    • Boissel JP. Note sur l'épistémiologie de la pharmacologie clinique: confrontation à l'approche de Karl Popper. Therapie 1999; 54: 67-73
    • (1999) Therapie , vol.54 , pp. 67-73
    • Boissel, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.