Long-term prospective randomized study comparing two different regimens of oxybutynin as a treatment for detrusor overactivity

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 119, Issue 2, 2005, Pages 237-241

  Salvatore, Stefano ^a,e   Khullar, Vikram ^c   Cardozo, Linda ^b   Milani, Rodolfo ^a   Athanasiou, Stavros ^b   Kelleher, Con ^d  

^a UNIVERSITY OF MILAN   (Italy)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

^c ST MARY S HOSPITAL   (United Kingdom)

^d ST THOMAS HOSPITAL   (United Kingdom)

^e NONE   (Italy)

Author keywords

Efficacy; Oxybutynin; Starting dose; Tolerance

Indexed keywords

OXYBUTYNIN;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DETRUSOR DYSSYNERGIA; DISEASE DURATION; DIZZINESS; DOSE CALCULATION; DROWSINESS; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG WITHDRAWAL; DRY NOSE; EYE DISEASE; FEMALE; HEADACHE; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MEDICAL ASSESSMENT; NAUSEA; PATIENT COMPLIANCE; PATIENT INFORMATION; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; STATISTICAL ANALYSIS; TACHYCARDIA; THROAT DISEASE; VISUAL IMPAIRMENT; XEROSTOMIA;

EID: 16244393404     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2004.07.042     Document Type: Article

References (18)

1. S. Khullar, L. Salvatore, A. Cardozo, S.K. Yip, and C.J. Kelleher The importance of urinary symptoms and urodynamic parameters in quality of life assessment Neurourol Urodyn 14 1995 540 542
2. P. Abrams, L. Cardozo, M. Fall, D. Griffiths, P. Rosier, and U. Ulmsten The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the International Continence Society Neurourol Urodyn 21 2002 167 178
3. C.J. Kelleher, L.D. Cardozo, V. Khullar, and S. Salvatore A new questionnaire to assess the quality of life of urinary incontinent women Br J Obstet Gynaecol 104 1997 1374 1379
4. J. Malone Lee Lower urinary tract function in late life D. Rushton Marceled Handbook of neurourology 1994 Dekker New York 349 368
5. H.Y. Leung, S.K. Yip, C. Cheon, Y.S. Liu, J. Lau, and H.K. Wong A randomized controlled trial of tolterodine and oxybutynin on tolerability and clinical efficacy for treating Chinese women with an overactive bladder BJU Int 90 4 2002 375 380
6. J. Hay-Smith, P. Herbison, G. Ellis, and K. Moore Anticholinergic drugs versus placebo for overactive bladder syndrome in adults Cochrane Database Syst Rev 3 2002 CD003781
7. J.G. Lee, J.Y. Hong, M.S. Choo, H.Y. Kwon, Y. Chung do, and K.S. Lee Tolterodine: as effective but better tolerated than oxybutynin in Asian patients with symptoms of overactive bladder Int J Urol 9 5 2002 247 552
8. P. Abrams Evidence for the efficacy and safety of tolterodine in the treatment of overactive bladder Expert Opin Pharmacother 2 10 2001 1685 1701
9. A. Todorova, B. Vonderheid-Guth, and W. Dimpfel Effects of tolterodine, trospium chloride, and oxybutynin on the central nervous system J Clin Pharmacol 41 6 2001 636 644
10. C.J. Kelleher, L.D. Cardozo, V. Khullar, and S. Salvatore A medium term analysis of the sbjective efficacy of treatment for women with detrusor instability and low bladder compliance Br J Obstet Gynaecol 104 1997 988 993
11. J. Malone-Lee, D. Lubel, and G. Szonoi Low dose oxybutynin for the unstable bladder Br Med J 304 1992 595 597
12. J. Douchamps, F. Derenne, A. Stockis, D. Ganji, M. Juvent, and A. Herchuelz The pharmacokinetics of oxybutynin in man Eur J Clin Pharmacol 35 1988 515 520
13. K.M. Hughes, J.C. Lang, R. Lazare, D. Gordon, S.L. Stanton, and J. Malone-Lee Measurement of oxybutynin and its N-desmethyloxybutynin metabolite in plasma, and its application to pharmacokinetic studies in young, elderly and frail elderly subjects Xenobiotica 22 1992 859 869
14. P. Abrams, J.G. Blaivas, S.L. Stanton, and J.T. Andersen The standardisation of terminology of lower urinary tract function Br J Obstet Gynaecol 97 Suppl 6 1990 1 16
15. Altman DG, How large a sample? in: SM., Gore, DG., Altman, editors. Statistics in Practice, London: British Medical Association, p. 6-8.
16. J.A. Fantl, W.G. Hurt, and L.J. Dunn Detrusor instability syndrome: the use of bladder retraining drills with and without anticholinergics Am J Obstet Gynecol 140 1981 885
17. M.A. Aitchison, R. Carter, P. Paterson, and B. Ferrie Is the treatment of urgency incontinence a placebo response? Results of a five-year follow up Br J Urol 64 1989 478 480
18. H.H. Meyhoff, T.C. Gerstenberg, and J. Nordling Placebo: the drug of choice in female motor and urge incontinence Br J Urol 55 1983 34 37