Chiral arylpyrrolidinols: Preparation and biological profile

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 9, 2005, Pages 3117-3126

  Collina, Simona ^a   Rossi, Daniela ^a   Loddo, Guya ^a   Barbieri, Annalisa ^a   Lanza, Enrica ^a   Linati, Laura ^a   Alcaro, Stefano ^b   Gallelli, Andrea ^b   Azzolina, Ornella ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

Antinociceptive activity; Arylpyrrolidinols; Enantioselective synthesis; Molecular modeling

Indexed keywords

1 METHYL 3 HYDROXY 3 (4 BIPHENYL)PYRROLIDINE DEXTRO LEVO TARTRATE; 1 METHYL 3 HYDROXY 3 NAPHTHALEN 2 YLPYRROLIDINE DEXTRO LEVO TARTRATE; 1,2 DIMETHYL 3 HYDROXY 3 (4 BENZYLOXYPHENYL)PYRROLIDINE; 1,2 DIMETHYL 3 HYDROXY 3 (4 BIPHENYL)PYRROLIDINE; 1,2 DIMETHYL 3 HYDROXY 3 (4 CHLOROPHENYL)PYRROLIDINE DEXTRO LEVO TARTRATE; 1,2 DIMETHYL 3 HYDROXY 3 (6 FLUORONAPHTHALEN 2 YL)PYRROLIDINE; 1,2 DIMETHYL 3 HYDROXY 3 (6 METHOXYNAPHTHALEN 2 YL)PYRROLIDINE; 1,2 DIMETHYL 3 HYDROXY 3 NAPHTHALEN 2 YLPYRROLIDINE; 1,2 DIMETHYL 3 HYDROXY 3 PHENYLPYRROLIDINE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHIRALITY; CHRONIC PAIN; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENANTIOMER; EXPERIMENTAL TEST; FORMALIN TEST; HOT PLATE TEST; IN VIVO STUDY; MALE; MOTOR COORDINATION; MOUSE; NOCICEPTION; NONHUMAN; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

EID: 16244392433     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.02.054     Document Type: Article

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