Mycophenolate mofetil inhibits intimal hyperplasia and attenuates the expression of genes favouring smooth muscle cell proliferation and migration

Transplantation Proceedings

Volumn 37, Issue 1, 2005, Pages 164-166

  Waller, J R ^a,b   Brook, N R ^a   Bicknell, G R ^a   Murphy, G J ^a   Nicholson, M L ^a  

^a LEICESTER GENERAL HOSPITAL   (United Kingdom)

^b Mental Illness Unit General Hospital   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN INHIBITOR; COLLAGEN TYPE 3; CYCLOSPORIN; METALLOPROTEINASE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; TACROLIMUS; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; CALCULATION; CELL HYPERPLASIA; CELL MIGRATION; CELL PROLIFERATION; COMMON CAROTID ARTERY; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFICACY; EXTRACELLULAR MATRIX; GENE EXPRESSION; MALE; MORPHOMETRICS; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; STAINING;

EID: 16244392430     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2005.01.049     Document Type: Conference Paper

References (6)

1. M.E. Billingham Histopathology of graft coronary disease J Heart Lung Transplant 3 1992 538
2. L.C. Paul Adverse effects of immunosuppressive drugs on long-term graft outcome Transplant Proc 30 1998 4001
3. R.N. Salomon, C.C.W. Hughes, F.J. Schoen Human transplant coronary arteriosclerosis: evidence for chronic immune reaction to activated graft endothelium Am J Pathol 138 1991 791
4. G.A.A. Ferns, E.W. Raines, K.H. Sprugel Inhibition of neointimal smooth muscle cell accumulation after angioplasty by an antibody to PDGF Science 253 1991 1129
5. N.E. Olson, S. Chao, V. Lindner Intima smooth muscle cell proliferation after balloon catheter injury: the role of basic fibroblast factor Am J Pathol 140 1992 1017
6. C.A. Allison, E.M. Eugui, H.W. Sollinger Mycophenolate mofetil (RS 61443): mechanism of action and effects of in transplantation Transplant Rev 7 1993 129