Somatostatin receptor imaging in vivo by planar scintigraphy facilitates the diagnosis of canine insulinomas

Journal of Veterinary Internal Medicine

Volumn 19, Issue 2, 2005, Pages 168-176

  Garden, Oliver A ^a,c,d   Reubi, Jean Claude ^b   Dykes, Nathan L ^a   Yeager, Amy E ^a   McDonough, Sean P ^a   Simpson, Kenneth W ^a  

^a Cornell University ^*  (United States)

^b UNIVERSITY OF BERN   (Switzerland)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

Autoradiography; Histopathology; Indium 111 pentetreotide; Neuroendocrine tumor; Octreotide; Pancreatic; Radioligand

Indexed keywords

INDIUM; IODINE 125; LEUCINE; OCTREOTIDE; PENTETREOTIDE IN 111; RADIOLIGAND; SOMATOSTATIN 28; SOMATOSTATIN RECEPTOR; TRYPTOPHAN; TYROSINE;

ACCURACY; AUTORADIOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DOG; FEMALE; HYPOGLYCEMIA; INSULINOMA; MALE; NONHUMAN; PANCREAS TUMOR; PREDICTION; REVIEW; SCINTIGRAPHY; TUMOR LOCALIZATION;

ANIMALS; AUTORADIOGRAPHY; DOG DISEASES; DOGS; INDIUM RADIOISOTOPES; INSULINOMA; PANCREATIC NEOPLASMS; RECEPTORS, SOMATOSTATIN;

CANIS FAMILIARIS;

EID: 16244387313     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2005)19<168:SRIIVB>2.0.CO;2     Document Type: Review

References (44)

1. Elic M, Zerbe C. Insulinoma in dogs, cats and ferrets. Compend Cont Educ Pract Vet 1995;17:51-59.
2. Menegaux F, Schmitt G, Mercadler H, Chigot J. Pancreatic insulinomas. Am J Surg 1993;165:243-248.
3. Steiner J, Bruyette D. Canine insulinoma. Compend Cont Educ Pract Vet 1996;18:13-24.
4. Kraje A. Hypoglycemia and irreversible neurologic complications in a cat with insulinoma. J Am Vet Med Assoc 2003;223:812-814.
5. Fenton A. Pancreatic insulin-secreting neoplasia in a 9-year-old Afghan Hound. Can Vet J 2003;44:918-920.
6. Burns A, Dackiw A. Insulinoma. Curr Treat Options Oncol 2003;4:309-317.
7. Leifer C, Peterson M, Matus R. Insulin-secreting tumor: Diagnosis and medical and surgical management in 55 dogs. J Am Vet Med Assoc 1986;188:60-64.
8. Kruth S, Feldman E, Kennedy P. Insulin-secreting islet cell tumors: Establishing a diagnosis and the clinical course for 25 dogs. J Am Vet Med Assoc 1982;181:54-58.
9. Dunn J, Bostock D, Herrtage M, et al. Insulin-secreting tumours of the canine pancreas: Clinical and pathological features of 11 cases. J Small Anim Pract 1993;34:325-331.
10. Caywood D, Klausner J, O'Leary T, et al. Pancreatic insulin-secreting neoplasms: Clinical, diagnostic, and prognostic features in 73 dogs J Am Anim Hosp Assoc 1988;24:577-584.
11. Trifonidou M, Kirpensteijn J, Robben J. A retrospective evaluation of 51 dogs with insulinoma. Vet Q 1998;20:S114-S115.
12. Schrauwen E, Ham LV, Desmidt M, Hoorens J. Peripheral polyneuropathy associated with insulinoma in the dog: Clinical, pathological, and electrodiagnostic features. Prog Vet Neurol 1996;7:16-19.
13. Shahar R, Rousseaux C, Steiss J. Peripheral polyneuropathy in a dog with functional islet B-cell tumor and widespread metastasis. J Am Vet Med Assoc 1985;187:175-177.
14. Proye C, Malvaux P, Pattou F, et al. Noninvasive imaging of insulinomas and gastrinomas with endoscopic ultrasonography and somatostatin receptor scintigraphy. Surgery 1998;124:1134-1144.
15. Krenning E, Kwekkeboom D, Oei H, et al. Somatostatin-receptor scintigraphy in gastroenteropancreatic tumors. Ann N Y Acad Sci 1994;733:416-424.
16. Warner R, O'Dorisio T. Radiolabeled peptides in diagnosis and tumor imaging: Clinical overview. Semin Nucl Med 2002;32:79-83.
17. Lurye J, Behrend E. Endocrine tumors. Vet Clin North Am Small Anim Pract 2001;31:1083-1110.
18. Reubi J, Haecki W, Lamberts S. Hormone-producing gastrointestinal tumors contain a high density of somatostatin receptors. J Clin Endocrinol Metab 1987;65:1127-1134.
19. Schirmer W, Melvin W, Rush R, et al. Indium-111-pentetreotide scanning versus conventional imaging techniques for the localization of gastrinoma. Surgery 1995;118:1105-1114.
20. Lamberts S, Krenning E, Reubi J. The role of somatostatin and its analogs in the diagnosis and treatment of tumors. Endocrinol Rev 1991;12:450-482.
21. Altschul M, Simpson K, Dykes N, et al. Evaluation of somatostatin analogues for the detection and treatment of gastrinoma in a dog. J Small Anim Pract 1997;38:286-291.
22. Buchanan JW, Boggs LS, Dewan S, et al. Left atrial paraganglioma in a dog: Echocardiography, surgery, and scintigraphy. J Vet Intern Med 1998;12:109-115.
23. Lester N, Newell S, Hill R, Lanz O. Scintigraphic diagnosis of insulinoma in a dog. Vet Radiol Ultrasound 1999;40:174-178.
24. Robben J, Visser-Wisselaar H, Rutteman G, et al. In vitro and in vivo detection of functional somatostatin receptors in canine insulinomas. J Nucl Med 1997;38:1036-1042.
25. Reubi J, Waser B, Schaer J, Laissue J. Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands. Eur J Nucl Med 2001;28:836-846.
26. Reubi J, Schaer J, Wenger S, et al. SST3-selective potent peptidic somatostatin receptor antagonists. Proc Natl Acad Sci USA 2000;97:13973-13978.
27. Reubi J, Kvols L, Waser B, et al. Detection of somatostatin receptors in surgical and percutaneous needle biopsy samples of carcinoids and islet cell carcinomas. Cancer Res 1990;50:5969-5977.
28. Dunn J, Heath M, Herrtage M, et al. Diagnosis of insulinoma in the dog: A study of 11 cases. J Small Anim Pract 1992;33:514-520.
29. Siliart B, Stambouli F. Laboratory diagnosis of insulinoma in the dog: A retrospective study and a new diagnostic procedure. J Small Anim Pract 1996;37:367-370.
30. McKenzie K, Hind C, Farquharson M, et al. Demonstration of insulin production and storage in insulinomas by in situ hybridization and immunocytochemistry. J Pathol 1997;181:218-222.
31. Lamb C, Simpson K, Boswood A, Matthewman L. Ultrasonography of pancreatic neoplasia in the dog: A retrospective review of 16 cases. Vet Rec 1995;137:65-68.
32. Boukhman M, Karam J, Shaver J, et al. Localization of insulinomas. Arch Surg 1999;134:818-823.
33. Galiber A, Reading C, Charboneau J, et al. Localization of pancreatic insulinoma: Comparison of pre- and intraoperative US with CT and angiography. Radiology 1988;166:405-408.
34. Machado M, Cimha JD, Jukemura J, et al. Insulinoma: Diagnostic strategies and surgical treatment. A 22-year experience. Hepatogastroenterology 2001;48:854-858.
35. O'Hanlon D, Clarke E, Fenlon H, et al. Insulinoma of the pancreas. Am J Surg 2001;182:73-74.
36. Chatziioannou A, Kehagias D, Mourikis D, et al. Imaging and localization of pancreatic insulinomas. Clin Imaging 2001;25:275-283.
37. Gouya H, Vignaux O, Augui J, et al. CT. endoscopic sonography, and a combined protocol for preoperative evaluation of pancreatic insulinomas. Am J Roentgenol 2003;181:987-992.
38. Robben J, Reubi J-C, Pollak Y, Voorhout G. Biodistribution of [111In-DTPA-D-Phe1]-octreotide in dogs: Uptake in the stomach and intestines but not the spleen points towards interspecies differences. Nucl Med Biol 2003;30:225-232.
39. Wangberg B, Forssell-Aronsson E, Tisell L, et al. Intraoperative detection of somatostatin-receptor-positive neuroendocrine tumour using indium-111-labelled DTPA-D-Phe1-octreotide. Br J Cancer 1996;73:770-775.
40. Fingeroth J, Smeak D. Intravenous methylene blue infusion for intraoperative identification of pancreatic islet-cell tumors in dogs. Part II: Clinical trials and results in four dogs. J Am Anim Hosp Assoc 1988;24:175-182.
41. Dickinson C, DelValle J, Todisco A, et al. Canine prosomatostatin: Isolation of a cDNA, regulation of gene expression, and characterization of post-translational processing intermediates. Regul Pept 1996;67:145-152.
42. Bertherat J, Tenenbaum F, Perlemoine K, et al. Somatostatin receptors 2 and 5 are the major somatostatin receptors in insulinomas: An in vivo and in vitro study. J Clin Endocrinol Metab 2003;88:5353-5360.
43. Otte A, Jermann E, Behe M, et al. DOTATOC: A powerful new tool for receptor-mediated radionuclide therapy. Eur J Nucl Med 1997;24:792-795.
44. Jong MD, Valkema R, Jamar F, et al. Somatostatin receptor-targeted radionuclide therapy of tumors: Preclinical and clinical findings. Semin Nucl Med 2002;32:133-140.