Interleukin 8 dimerization as a mechanism for regulation of neutrophil adherence-dependent oxidant production

Shock

Volumn 23, Issue 4, 2005, Pages 371-376

  Williams, Mark A ^a   Cave, Cindy M ^a   Quaid, Gina ^a   Robinson, Chad ^a   Daly, Thomas J ^b   Witt, Dan ^c   Lentsch, Alex B ^a   Solomkin, Joseph S ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b REGENERON PHARMACEUTICALS INC   (United States)

^c REPLIGEN CORPORATION   (United States)

Author keywords

Chemokines; Cytokine receptors; Free radicals; Leukocyte

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; DIMER; ELASTASE INHIBITOR; GLYCOSAMINOGLYCAN; INTERLEUKIN 8; MONOMER; OXIDIZING AGENT; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BINDING AFFINITY; CALCIUM TRANSPORT; CELL ADHESION; CELL INTERACTION; CELL ISOLATION; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIMERIZATION; ENZYME RELEASE; HUMAN; HUMAN CELL; NEUTROPHIL; PROTEIN PROTEIN INTERACTION; RESPIRATORY BURST;

BINDING, COMPETITIVE; CALCIUM; CELL ADHESION; CHEMOKINES; CHEMOTAXIS; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; GLYCOSAMINOGLYCANS; HUMANS; HYDROGEN PEROXIDE; INTERLEUKIN-8; MUTATION; NEUTROPHILS; OXIDANTS; OXYGEN; PANCREATIC ELASTASE; RADIOLIGAND ASSAY; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; RESPIRATORY BURST; TUMOR NECROSIS FACTOR-ALPHA;

EID: 16244373398     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000158140.58335.54     Document Type: Article

References (38)

1. Ahuja SK, Murphy PM: The CXC chemokines growth-regulated oncogene (GRO) α, GROβ, GROγ, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor. J Biol Chem 271:20545-20550, 1996.
2. Campbell JJ, Qin S, Bacon KB, Mackay CR, Butcher EC: Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells. J Cell Biol 134:255-266, 1996.
3. Imaizumi T, Albertine KH, Jicha DL, McIntyre TM, Prescott SM, Zimmerman GA: Human endothelial cells synthesize ENA-78: relationship to IL-8 and to signaling of PMN adhesion. Am J Respir Cell Mol Biol 17:181-192, 1997.
4. Jones SA, Wolf M, Qin S, Mackay CR, Baggiolini M: Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2. Proc Natl Acad Sci USA 93:6682-6686, 1996.
5. Koch AE, Kunkel SL, Harlow LA, Mazarakis DD, Haines GK, Burdick MD, Pope RM, Walz A, Stricter RM: Epithelial neutrophil activating peptide-78: a novel chemotactic cytokine for neutrophils in arthritis. J Clin Invest 94:1012-1018, 1994.
6. Ludwig A, Petersen F, Zahn S, Gotze O, Schroder JM, Flad HD, Brandt E: The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2. Blood 90:4588-4597, 1997.
7. Baldwin ET, Weber IT, St Charles R, Xuan JC, Appella E, Yamada M, Matsushima K, Edwards BF, Clore GM, Gronenborn AM, et al.: Crystal structure of interleukin 8: symbiosis of NMR and crystallography. Proc Natl Acad Sci USA 88:502-506, 1991.
8. Clore GM, Gronenborn AM: NMR and x-ray analysis of the three-dimensional structure of interleukin-8. Cytokine 4:18-40, 1992.
9. Hanzawa H, Haruyama H, Konishi K, Watanabe K, Tsurufuji S: Solution structure of CINC/Gro investigated by heteronuclear NMR. J Biochem (Tokyo) 123:62-70, 1998.
10. Daly TJ, LaRosa GJ, Dolich S, Maione TE, Cooper S, Broxmeyer HE: High activity suppression of myeloid progenitor proliferation by chimeric mutants of interleukin 8 and platelet factor 4. J Biol Chem 270:23282-23292, 1995.
11. Baggiolini M, Dewald B, Moser B: Interleukin-8 and related chemotactic cytokines: CXC and CC chemokines. Adv Immunol 55:97-179, 1994.
12. Dang PM, Cross AR, Quinn MT, Babior BM: Assembly of the neutrophil respiratory burst oxidase: a direct interaction between p67PHOX and cytochrome b558 II. Proc Natl Acad Sci USA 99:4262-4265, 2002.
13. Gimbrone MA, Obin MS, Brock AF, Luis EA, Hass PE, Hebert CA, Yip YK, Leung DW, Lowe DG, Kohr WJ: Endothelial interleukin-8: a novel inhibitor of leukocyte-endothelial interactions. Science 246:1601-1603, 1989.
14. Hechtman DH, Cybulsky MI, Fuchs HJ, Baker JB, Gimbrone MA: Intravascular IL-8. Inhibitor of polymorphonuclear leukocyte accumulation at sites of acute inflammation. J Immunol 147:883-892, 1991.
15. Luscinskas FW, Kiely JM, Ding H, Obin MS, Hebert CA, Baker JB, Gimbrone MA: In vitro inhibitory effect of IL-8 and other chemoattractants on neutrophil-endothelial adhesive interactions. J Immunol 149:2163-2171, 1992.
16. Dewas C, Fay M, Gougerot-Pocidalo MA, El Benna J: The mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway is involved in formyl-methionyl-leucyl-phenylalanine-induced p47phox phosphorylation in human neutrophils. J Immunol 165:5238-5244, 2000.
17. El Benna J, Faust RP, Johnson JL, Babior BM: Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A, and a mitogen-activated protein kinase. J Biol Chem 271:6374-6378, 1996.
18. Kitayama J, Carr MW, Roth SJ, Buccola J, Springer TA: Contrasting responses to multiple chemotactic stimuli in transendothelial migration: heterologous desensitization in neutrophils and augmentation of migration in eosinophils. J Immunol 158:2340-2349, 1997.
19. Richardson RM, Ali H, Tomhave ED, Haribabu B, Snyderman R: Cross-desensitization of chemoattractant receptors occurs at multiple levels. Evidence for a role for inhibition of phospholipase C activity. J Biol Chem 270:27829-27833, 1995.
20. Cummings CJ, Martin TR, Frevert CW, Quan JM, Wong VA, Mongovin SM, Hagen TR, Steinberg KP, Goodman RB: Expression and function of the chemokine receptors CXCR1 and CXCR2 in sepsis. J Immunol 162:2341-2346, 1999.
21. Hoch RC, Rodriguez R, Manning T, Bishop M, Mead P, Shoemaker WC, Abraham E: Effects of accidental trauma on cytokine and endotoxin production. Crit Care Med 21:839-845, 1993.
22. Roumen RM, Hendriks T, van der Ven-Jongekrijg J, Nieuwenhuijzen GA, Sauerwein RW, van der Meer JW, Goris RJ: Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma. Relation with subsequent adult respiratory distress syndrome and multiple organ failure. Ann Surg 218:769-776, 1993.
23. Schnitzel W, Monschein U, Besemer J: Monomer-dimer equilibria of interleukin-8 and neutrophil-activating peptide 2. Evidence for IL-8 binding as a dimer and oligomer to IL-8 receptor B. J Leukocyte Biol 55:763-770, 1994.
24. Dang PM, Cross AR, Babior BM: Assembly of the neutrophil respiratory burst oxidase: a direct interaction between p67PHOX and cytochrome b558. Proc Natl Acad Sci USA 98:3001-3005, 2001.
25. Paolini JF, Willard D, Consler T, Luther M, Krangel MS: The chemokines IL-8, monocyte chemoattractant protein-1, and 1-309 are monomers at physiologically relevant concentrations. J Immunol 153:2704-2717, 1994.
26. Regier DS, Greene DG, Sergeant S, Jesaitis AJ, McPhail LC: Phosphorylation of p22phox is mediated by phospholipase D-dependent and -independent mechanisms. Correlation of NADPH oxidase activity and p22phox phosphorylation. J Biol Chem 275:28406-28412, 2000.
27. Horcher M, Rot A, Aschauer H, Besemer J: IL-8 derivatives with a reduced potential to form homodimers are fully active in vitro and in vivo. Cytokine 10:1-12, 1998.
28. Solomkin JS, Nelson RD, Chenoweth DE, Solem LD, Simmons RL: Regulation of neutrophil migratory function in burn injury by complement activation products. Ann Surg 200:742-746, 1984.
29. Solomkin JS, Tindal CJ, Cave CM, Zemlan F: Regulation of TNF-α receptor expression on human neutrophils by various cell activating factors. J Surg Res 56:261-266, 1994.
30. Faust LR, El Benna J, Babior BM, Chanock SJ: The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis. J Clin Invest 96:1499-1505, 1995.
31. Hoogewerf AJ, Kuschen GS, Proudfoot AE, Borlat F, dark-Lewis I, Power CA, Wells TN: Glycosaminoglycans mediate cell surface oligomerization of chemokines. Biochemistry 36:13570-13578, 1997.
32. Kuschert GS, Coulin F, Power CA, Proudfoot AE, Hubbard RE, Hoogewerf AJ, Wells TN: Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses. Biochemistry 38:12959-12968, 1999.
33. Webb LM, Ehrengruber MU, dark-Lewis I, Baggiolini M, Rot A: Binding to heparin sulfate or heparin enhances neutrophil responses to interleukin 8. Proc Natl Acad Sci USA 90:7158-7162, 1993.
34. Rajarathnam K, Sykes BD, Kay CM, Dewald B, Geiser T, Baggiolini M, dark-Lewis I: Neutrophil activation by monomeric interleukin-8. Science 264:90-92, 1994.
35. Babior BM: The activity of leukocyte NADPH oxidase: regulation by p47PHOX cysteine and serine residues. Antioxid Redox Signal 4:35-38, 2002.
36. Skelton NJ, Quan C, Reilly D, Lowman H: Structure of a CXC chemokine-receptor fragment in complex with interleukin-8. Structure 7:157-168, 1999.
37. Cinamon G, Shinder V, Shamri R, Alon R: Chemoattractant signals and β2 integrin occupancy at apical endothelial contacts combine with shear stress signals to promote transendothelial neutrophil migration. J Immunol 173:7282-7291, 2004.
38. Alon R, Luscinskas FW: Crawling and INTEGRating apical cues. Nat Immunol 5:351-353, 2004.