메뉴 건너뛰기




Volumn 10, Issue 3, 2005, Pages 215-224

Chemoradiation after surgery for high-risk head and neck cancer patients: How strong is the evidence?

Author keywords

Chemoradiation; Chemotherapy; Head and neck; Radiotherapy; Squamous cell carcinoma; Surgery

Indexed keywords

CETUXIMAB; CISPLATIN; FLUOROURACIL;

EID: 16244371725     PISSN: 10837159     EISSN: None     Source Type: Journal    
DOI: 10.1634/theoncologist.10-3-215     Document Type: Review
Times cited : (121)

References (61)
  • 1
    • 0026763223 scopus 로고
    • Adjuvant chemotherapy for resectable squamous cell carcinomas of the head and neck: Report on Intergroup Study 0034
    • Laramore GE, Scott CB, al-Sarraf M et al. Adjuvant chemotherapy for resectable squamous cell carcinomas of the head and neck: report on Intergroup Study 0034. Int J Radiat Oncol Biol Phys 1992;23:705-713.
    • (1992) Int J Radiat Oncol Biol Phys , vol.23 , pp. 705-713
    • Laramore, G.E.1    Scott, C.B.2    Al-Sarraf, M.3
  • 2
    • 0025373647 scopus 로고
    • Adjuvant chemotherapy in head and neck cancer
    • Stell PM, Rawson NS. Adjuvant chemotherapy in head and neck cancer. Br J Cancer 1990;61:779-787.
    • (1990) Br J Cancer , vol.61 , pp. 779-787
    • Stell, P.M.1    Rawson, N.S.2
  • 3
    • 0028852938 scopus 로고
    • An overview of randomised controlled trials of adjuvant chemotherapy in head and neck cancer
    • Munro AJ. An overview of randomised controlled trials of adjuvant chemotherapy in head and neck cancer. Br J Cancer 1995;71:83-91.
    • (1995) Br J Cancer , vol.71 , pp. 83-91
    • Munro, A.J.1
  • 4
    • 0029868441 scopus 로고    scopus 로고
    • Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region. A meta-analysis of prospective and randomized trials
    • El-Sayed S, Nelson N. Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region. A meta-analysis of prospective and randomized trials. J Clin Oncol 1996;14:838-847.
    • (1996) J Clin Oncol , vol.14 , pp. 838-847
    • El-Sayed, S.1    Nelson, N.2
  • 5
    • 0034681783 scopus 로고    scopus 로고
    • Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: Three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer
    • Pignon JP, Bourhis J, Domenge C et al. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000;355:949-955.
    • (2000) Lancet , vol.355 , pp. 949-955
    • Pignon, J.P.1    Bourhis, J.2    Domenge, C.3
  • 6
    • 0034975986 scopus 로고    scopus 로고
    • Choosing a concomitant chemotherapy and radiotherapy regimen for squamous cell head and neck cancer: A systematic review of the published literature with subgroup analysis
    • Browman GP, Hodson DI, Mackenzie RJ et al. Choosing a concomitant chemotherapy and radiotherapy regimen for squamous cell head and neck cancer: a systematic review of the published literature with subgroup analysis. Head Neck 2001;23:579-589.
    • (2001) Head Neck , vol.23 , pp. 579-589
    • Browman, G.P.1    Hodson, D.I.2    Mackenzie, R.J.3
  • 7
    • 0026001207 scopus 로고
    • The effect of local-regional control on distant metastatic dissemination in carcinoma of the head and neck: Results of an analysis from the RTOG Head and Neck Database
    • Leibel SA, Scott CB, Mohiuddin M et al. The effect of local-regional control on distant metastatic dissemination in carcinoma of the head and neck: results of an analysis from the RTOG Head and Neck Database. J Radiat Oncol Biol Phys 1991;21:549-556.
    • (1991) J Radiat Oncol Biol Phys , vol.21 , pp. 549-556
    • Leibel, S.A.1    Scott, C.B.2    Mohiuddin, M.3
  • 8
    • 0024322497 scopus 로고
    • Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer
    • Weissberg J, Son Y, Papac R. Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer. Int J Radiat Oncol Biol Phys 1989;17:3-9.
    • (1989) Int J Radiat Oncol Biol Phys , vol.17 , pp. 3-9
    • Weissberg, J.1    Son, Y.2    Papac, R.3
  • 9
    • 0025975392 scopus 로고
    • Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced squamous cell carcinoma of the head and neck: Preliminary report of a randomized trial
    • Bachaud JM, David JM, Boussin G et al. Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced squamous cell carcinoma of the head and neck: preliminary report of a randomized trial. Int J Radiat Oncol Biol Phys 1991;20:243-246.
    • (1991) Int J Radiat Oncol Biol Phys , vol.20 , pp. 243-246
    • Bachaud, J.M.1    David, J.M.2    Boussin, G.3
  • 10
    • 0026634269 scopus 로고
    • Simultaneous chemoradiation in the treatment of advanced head and neck cancer
    • Weissler M, Melin S, Sailer S et al. Simultaneous chemoradiation in the treatment of advanced head and neck cancer. Arch Otolaryngol Head Neck Surg 1992;118:806-810.
    • (1992) Arch Otolaryngol Head Neck Surg , vol.118 , pp. 806-810
    • Weissler, M.1    Melin, S.2    Sailer, S.3
  • 11
    • 0027358606 scopus 로고
    • Mitomycin C as an adjunct to post-operative radiation therapy in squamous cell carcinoma of the head and neck: Results from two randomized clinical trials
    • Haffty B, Son Y, Sasaki C et al. Mitomycin C as an adjunct to post-operative radiation therapy in squamous cell carcinoma of the head and neck: results from two randomized clinical trials. Int J Radiat Oncol Biol Phys 1993;27:241-250.
    • (1993) Int J Radiat Oncol Biol Phys , vol.27 , pp. 241-250
    • Haffty, B.1    Son, Y.2    Sasaki, C.3
  • 12
    • 0030457015 scopus 로고    scopus 로고
    • Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced head and neck carcinoma: Final report of a randomized trial
    • Bachaud JM, Cohen-Jonathan E, Alzieu C et al. Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced head and neck carcinoma: final report of a randomized trial. Int J Radiat Oncol Biol Phys 1996;36:999-1004.
    • (1996) Int J Radiat Oncol Biol Phys , vol.36 , pp. 999-1004
    • Bachaud, J.M.1    Cohen-Jonathan, E.2    Alzieu, C.3
  • 13
    • 2342592623 scopus 로고    scopus 로고
    • Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer
    • Bernier J, Domenge C, Ozsahin M et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004;350:1945-1952.
    • (2004) N Engl J Med , vol.350 , pp. 1945-1952
    • Bernier, J.1    Domenge, C.2    Ozsahin, M.3
  • 14
    • 2342517421 scopus 로고    scopus 로고
    • Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck
    • 350
    • Cooper JS, Pajak TF, Forastiere AA et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 350;19:1937-1944.
    • N Engl J Med , vol.19 , pp. 1937-1944
    • Cooper, J.S.1    Pajak, T.F.2    Forastiere, A.A.3
  • 15
    • 0014764496 scopus 로고
    • Radiotherapeutic management of surgical recurrences and postoperative residuals in tumors of the head and neck
    • Fletcher GH, Evers W. Radiotherapeutic management of surgical recurrences and postoperative residuals in tumors of the head and neck. Radiology 1970;95:185-188.
    • (1970) Radiology , vol.95 , pp. 185-188
    • Fletcher, G.H.1    Evers, W.2
  • 16
    • 0023558137 scopus 로고
    • Combined radiation therapy and surgery in the management of head and neck cancer: Final report of study 73-03 of the Radiation Therapy Oncology Group
    • Kramer S, Gelber RD, Snow JB et al. Combined radiation therapy and surgery in the management of head and neck cancer: final report of study 73-03 of the Radiation Therapy Oncology Group. Head Neck Surg 1987;10:19-30.
    • (1987) Head Neck Surg , vol.10 , pp. 19-30
    • Kramer, S.1    Gelber, R.D.2    Snow, J.B.3
  • 18
    • 0021364491 scopus 로고
    • Failure at the primary site following multimodality treatment in advanced head and neck cancer
    • Vikram B, Strong EW, Shah JP et al. Failure at the primary site following multimodality treatment in advanced head and neck cancer. Head Neck Surg 1984;6:720-723.
    • (1984) Head Neck Surg , vol.6 , pp. 720-723
    • Vikram, B.1    Strong, E.W.2    Shah, J.P.3
  • 19
    • 0019869514 scopus 로고
    • The extracapsular spread of tumors in cervical node metastasis
    • Johnson JT, Barnes EL, Myers EN et al. The extracapsular spread of tumors in cervical node metastasis. Arch Otolaryngol 1981;107:725-729.
    • (1981) Arch Otolaryngol , vol.107 , pp. 725-729
    • Johnson, J.T.1    Barnes, E.L.2    Myers, E.N.3
  • 20
    • 0015419068 scopus 로고
    • Management of cervical lymph node metastases in squamous cell carcinomas of the tonsillar fossa, base of tongue, supraglottic larynx and hypopharynx
    • Barkley HT Jr, Fletcher GH, Jesse RH et al. Management of cervical lymph node metastases in squamous cell carcinomas of the tonsillar fossa, base of tongue, supraglottic larynx and hypopharynx. Am J Surg 1972;124:462-467.
    • (1972) Am J Surg , vol.124 , pp. 462-467
    • Barkley Jr., H.T.1    Fletcher, G.H.2    Jesse, R.H.3
  • 21
    • 0019513299 scopus 로고
    • Postoperative chemotherapy versus postoperative cobalt-60 radiation therapy in patients with advanced oral carcinoma
    • Bitter K. Postoperative chemotherapy versus postoperative cobalt-60 radiation therapy in patients with advanced oral carcinoma. Head Neck Surg 1981;3:260.
    • (1981) Head Neck Surg , vol.3 , pp. 260
    • Bitter, K.1
  • 22
    • 0017139441 scopus 로고
    • Carcinoma of the oral cavity: Factors affecting treatment failure at the primary site and neck
    • Shah JT, Cendon AA, Farr HW et al. Carcinoma of the oral cavity: factors affecting treatment failure at the primary site and neck. Am J Surg 1976;132:504-507.
    • (1976) Am J Surg , vol.132 , pp. 504-507
    • Shah, J.T.1    Cendon, A.A.2    Farr, H.W.3
  • 23
    • 0019985053 scopus 로고
    • Radiotherapy of lymph node metastases in squamous cell carcinomas of the head and neck region
    • Bartelink H, Breur K, Hart G. Radiotherapy of lymph node metastases in squamous cell carcinomas of the head and neck region. Int J Radiat Oncol Biol Phys 1982;8:983-990.
    • (1982) Int J Radiat Oncol Biol Phys , vol.8 , pp. 983-990
    • Bartelink, H.1    Breur, K.2    Hart, G.3
  • 24
    • 0024318480 scopus 로고
    • A multivariate primary tumor control analysis in 465 patients treated by radical radiotherapy for carcinoma of the tonsillar region: Clinical and treatment parameters as prognostic factors
    • Bataini JP, Asselain B, Jaulerry C et al. A multivariate primary tumor control analysis in 465 patients treated by radical radiotherapy for carcinoma of the tonsillar region: clinical and treatment parameters as prognostic factors. Radiother Oncol 1989;14:265-277.
    • (1989) Radiother Oncol , vol.14 , pp. 265-277
    • Bataini, J.P.1    Asselain, B.2    Jaulerry, C.3
  • 25
    • 0022607376 scopus 로고
    • Regional outcome in oropharyngeal and pharyngolaryngeal cancers treated with high dose per fraction radiotherapy. Analysis of neck disease response in 1646 cases
    • Bernier J, Bataini JP. Regional outcome in oropharyngeal and pharyngolaryngeal cancers treated with high dose per fraction radiotherapy. Analysis of neck disease response in 1646 cases. Radiother Oncol 1986;6:87-103.
    • (1986) Radiother Oncol , vol.6 , pp. 87-103
    • Bernier, J.1    Bataini, J.P.2
  • 26
    • 0021258332 scopus 로고
    • Predicting the response of head and neck cancers to radiation therapy with a multivariate modelling system: An analysis of the RTOG head and neck cancer registry
    • Griffin TW, Pajak TF, Gillespie BW et al. Predicting the response of head and neck cancers to radiation therapy with a multivariate modelling system: an analysis of the RTOG head and neck cancer registry. Int J Radiat Oncol Biol Phys 1984;10:481-487.
    • (1984) Int J Radiat Oncol Biol Phys , vol.10 , pp. 481-487
    • Griffin, T.W.1    Pajak, T.F.2    Gillespie, B.W.3
  • 27
    • 0027212468 scopus 로고
    • Evaluation of the dose for post-operative radiation therapy of head and neck cancer: First report of a prospective randomized trial
    • Peters LJ, Goepfert H, Ang KK et al. Evaluation of the dose for post-operative radiation therapy of head and neck cancer: first report of a prospective randomized trial. Int J Radiat Oncol Biol Phys 1993;26:3-11.
    • (1993) Int J Radiat Oncol Biol Phys , vol.26 , pp. 3-11
    • Peters, L.J.1    Goepfert, H.2    Ang, K.K.3
  • 28
    • 0031720722 scopus 로고    scopus 로고
    • Precisely defining high-risk operable head and neck tumors based on RTOG#85-03 and RTOG#88-24: Targets for postoperative chemoradiotherapy?
    • Cooper JS, Pajak TF, Forastiere AA et al. Precisely defining high-risk operable head and neck tumors based on RTOG#85-03 and RTOG#88-24: targets for postoperative chemoradiotherapy? Head Neck 1998;20:588-594.
    • (1998) Head Neck , vol.20 , pp. 588-594
    • Cooper, J.S.1    Pajak, T.F.2    Forastiere, A.A.3
  • 29
    • 0030964407 scopus 로고    scopus 로고
    • Postoperative radiotherapy with concurrent cisplatin appears to improve locoregional control of advanced, resectable head and neck cancers: RTOG 88-24
    • Al-Sarraf M, Pajak TF, Byhardt RW et al. Postoperative radiotherapy with concurrent cisplatin appears to improve locoregional control of advanced, resectable head and neck cancers: RTOG 88-24. Int J Radiat Oncol Biol Phys 1997;37:777-782.
    • (1997) Int J Radiat Oncol Biol Phys , vol.37 , pp. 777-782
    • Al-Sarraf, M.1    Pajak, T.F.2    Byhardt, R.W.3
  • 30
    • 0027393591 scopus 로고
    • Implications of positive surgical margins
    • Jacobs J, Ahmad K, Casiano R et al. Implications of positive surgical margins. Laryngoscope 1993;103:64-68.
    • (1993) Laryngoscope , vol.103 , pp. 64-68
    • Jacobs, J.1    Ahmad, K.2    Casiano, R.3
  • 31
    • 0027376509 scopus 로고
    • Is a surgical resection leaving positive margins of benefit to the patient with locally advanced squamous cell carcinoma of the head and neck: A comparative study using the intergroup study 0034 and the Radiation Therapy Oncology Group head and neck database
    • Laramore GE, Scott CB, Schuller DE et al. Is a surgical resection leaving positive margins of benefit to the patient with locally advanced squamous cell carcinoma of the head and neck: a comparative study using the intergroup study 0034 and the Radiation Therapy Oncology Group head and neck database. J Radiat Oncol Biol Phys 1993;27:1011-1016.
    • (1993) J Radiat Oncol Biol Phys , vol.27 , pp. 1011-1016
    • Laramore, G.E.1    Scott, C.B.2    Schuller, D.E.3
  • 32
    • 0035501324 scopus 로고    scopus 로고
    • Brown Bw Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer
    • Ang KK, Trotti A. Brown BW et al. Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 2001;51:571-578.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 571-578
    • Ang, K.K.1    Trotti, A.2
  • 33
    • 0030458557 scopus 로고    scopus 로고
    • Postoperative radiotherapy for head and neck squamous cell carcinomas: Feasibility of a biphasic accelerated treatment schedule
    • Sanguineti G, Corvo R, Vitale V et al. Postoperative radiotherapy for head and neck squamous cell carcinomas: feasibility of a biphasic accelerated treatment schedule. Int J Radiat Oncol Biol Phys 1996;36:1147-1153.
    • (1996) Int J Radiat Oncol Biol Phys , vol.36 , pp. 1147-1153
    • Sanguineti, G.1    Corvo, R.2    Vitale, V.3
  • 34
    • 0031931595 scopus 로고    scopus 로고
    • Postoperative accelerated radiotherapy in high-risk squamous cell carcinoma of the head and neck: Long-term results of a prospective trial
    • Trotti A, Klotch D, Endicott J et al. Postoperative accelerated radiotherapy in high-risk squamous cell carcinoma of the head and neck: long-term results of a prospective trial. Head Neck 1998;20:119-123.
    • (1998) Head Neck , vol.20 , pp. 119-123
    • Trotti, A.1    Klotch, D.2    Endicott, J.3
  • 35
    • 16244363394 scopus 로고    scopus 로고
    • Head and neck cancer management: Which postoperative treatment best serves your patient?
    • Bernier J, Bentzen SM. Head and neck cancer management: which postoperative treatment best serves your patient? ASCO 2003 Educational Book, 306-312.
    • ASCO 2003 Educational Book , pp. 306-312
    • Bernier, J.1    Bentzen, S.M.2
  • 36
    • 0023115012 scopus 로고
    • Combined treatment of radiation and cisdiamminedichloroplatinum (II): A review of experimental and clinical data
    • Dewit L. Combined treatment of radiation and cisdiamminedichloroplatinum (II): a review of experimental and clinical data. Int J Radiat Oncol Biol Phys 1987;13:403-426.
    • (1987) Int J Radiat Oncol Biol Phys , vol.13 , pp. 403-426
    • Dewit, L.1
  • 37
    • 0023575637 scopus 로고
    • Combined radiotherapy and chemotherapy with bleomycin and methotrexate for advanced inoperable head and neck cancers: Update of a Northern California Oncology Group randomized trial
    • Fu KK, Phillips TL, Silverberg IY et al. Combined radiotherapy and chemotherapy with bleomycin and methotrexate for advanced inoperable head and neck cancers: update of a Northern California Oncology Group randomized trial. J Clin Oncol 1987;5:1410-1418.
    • (1987) J Clin Oncol , vol.5 , pp. 1410-1418
    • Fu, K.K.1    Phillips, T.L.2    Silverberg, I.Y.3
  • 38
    • 0024420591 scopus 로고
    • Combined modality treatment with radiotherapy and chemotherapy
    • Tannock IF. Combined modality treatment with radiotherapy and chemotherapy. Radiother Oncol 1989;16:83-101.
    • (1989) Radiother Oncol , vol.16 , pp. 83-101
    • Tannock, I.F.1
  • 39
    • 0021212107 scopus 로고
    • Adjuvant chemotherapy after surgery and radiation for stage III and IV head and neck cancer
    • Huang AT, Cole TB, Fishburn R et al. Adjuvant chemotherapy after surgery and radiation for stage III and IV head and neck cancer. Ann Surg 1984;200:195-199.
    • (1984) Ann Surg , vol.200 , pp. 195-199
    • Huang, A.T.1    Cole, T.B.2    Fishburn, R.3
  • 40
    • 0024318579 scopus 로고
    • Chemotherapy following surgery in head and neck cancer. A Radiation Therapy Oncology Group study
    • Jacobs JR, Pajak TF, Al-Sarraf M et al. Chemotherapy following surgery in head and neck cancer. A Radiation Therapy Oncology Group study. Am J Clin Oncol 1989;12:185-189.
    • (1989) Am J Clin Oncol , vol.12 , pp. 185-189
    • Jacobs, J.R.1    Pajak, T.F.2    Al-Sarraf, M.3
  • 41
    • 0023117824 scopus 로고
    • Adjuvant chemotherapy for high risk squamous cell carcinomas of the head and neck
    • Johnson JT, Myers EN, Schramm VL et al. Adjuvant chemotherapy for high risk squamous cell carcinomas of the head and neck. J Clin Oncol 1987;5:456-458.
    • (1987) J Clin Oncol , vol.5 , pp. 456-458
    • Johnson, J.T.1    Myers, E.N.2    Schramm, V.L.3
  • 42
    • 0024274529 scopus 로고
    • Adjuvant chemotherapy with vincristine, cyclophosphamide, and doxorubicin after radiotherapy in local-regional nasopharyngeal cancer: Results of a four-year multicenter randomized study
    • Rossi A, Molinari R, Boracchi P et al. Adjuvant chemotherapy with vincristine, cyclophosphamide, and doxorubicin after radiotherapy in local-regional nasopharyngeal cancer: results of a four-year multicenter randomized study. J Clin Oncol 1988;6:1401-1410.
    • (1988) J Clin Oncol , vol.6 , pp. 1401-1410
    • Rossi, A.1    Molinari, R.2    Boracchi, P.3
  • 43
    • 0025800614 scopus 로고
    • Radiotherapy with concomitant chemotherapy for head and neck cancer
    • Vokes EE, Awan AM, Weichselbaum RR. Radiotherapy with concomitant chemotherapy for head and neck cancer. Oncol Clin North Am 1991;5:753-767.
    • (1991) Oncol Clin North Am , vol.5 , pp. 753-767
    • Vokes, E.E.1    Awan, A.M.2    Weichselbaum, R.R.3
  • 44
    • 0025696133 scopus 로고
    • Cisplatin and radiation: Interaction probabilities and therapeutic possibilities
    • Begg AC. Cisplatin and radiation: interaction probabilities and therapeutic possibilities. Int J Radiat Oncol Biol Phys 1990;19:1183-1189.
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 1183-1189
    • Begg, A.C.1
  • 45
    • 0019429723 scopus 로고
    • Concomitant radiation therapy and cis-diamminedichloroplatinum (II) in patients with advanced head and neck cancer
    • Creagan ET, Fountain KS, Frytak S et al. Concomitant radiation therapy and cis-diamminedichloroplatinum (II) in patients with advanced head and neck cancer. Med Pediatr Oncol 1981;9:119-120.
    • (1981) Med Pediatr Oncol , vol.9 , pp. 119-120
    • Creagan, E.T.1    Fountain, K.S.2    Frytak, S.3
  • 46
    • 0026034634 scopus 로고
    • Concurrent cisplatin, infusional 5-fluorouracil, and conventionally fractionated radiation therapy in head and neck cancer: Dose-limiting mucosal toxicity
    • Denham JW, Abbott RL. Concurrent cisplatin, infusional 5-fluorouracil, and conventionally fractionated radiation therapy in head and neck cancer: dose-limiting mucosal toxicity. J Clin Oncol 1991;9:458-463.
    • (1991) J Clin Oncol , vol.9 , pp. 458-463
    • Denham, J.W.1    Abbott, R.L.2
  • 47
    • 0020618964 scopus 로고
    • Cisplatin sensitization to radiotherapy of squamous cell carcinomas of the head and neck
    • Leipzig B. Cisplatin sensitization to radiotherapy of squamous cell carcinomas of the head and neck. Am J Surg 1983;146:462-465.
    • (1983) Am J Surg , vol.146 , pp. 462-465
    • Leipzig, B.1
  • 48
    • 0032543663 scopus 로고    scopus 로고
    • Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer
    • Brizel DM, Albers ME, Fisher SR et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med 1998;338:1798-1804.
    • (1998) N Engl J Med , vol.338 , pp. 1798-1804
    • Brizel, D.M.1    Albers, M.E.2    Fisher, S.R.3
  • 49
    • 0031597441 scopus 로고    scopus 로고
    • Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancers
    • Dobrowsky W, Naude J, Widder J et al. Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancers. Int J Radiat Oncol Biol Phys 1998;42:803-806.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 803-806
    • Dobrowsky, W.1    Naude, J.2    Widder, J.3
  • 50
    • 0033572407 scopus 로고    scopus 로고
    • Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma
    • Calais G, Alfonsi M, Bardet E et al. Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Nat Cancer Inst 1999;91:2081-2086.
    • (1999) J Nat Cancer Inst , vol.91 , pp. 2081-2086
    • Calais, G.1    Alfonsi, M.2    Bardet, E.3
  • 51
    • 0034034509 scopus 로고    scopus 로고
    • Hyperfractionated radiotherapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: A prospective randomized trial
    • Jeremic C, Shibamoto Y, Milicic B et al. Hyperfractionated radiotherapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: a prospective randomized trial. J Clin Oncol 2000;18:1458-1464.
    • (2000) J Clin Oncol , vol.18 , pp. 1458-1464
    • Jeremic, C.1    Shibamoto, Y.2    Milicic, B.3
  • 52
    • 0034651902 scopus 로고    scopus 로고
    • Mature results of a phase HI randomized trial comparing concurrent chemoradiotherapy with radiation alone in patients with stage III and IV squamous cell carcinoma of the head and neck
    • Adelstein D, Lavertu P, Saxton J et al. Mature results of a phase HI randomized trial comparing concurrent chemoradiotherapy with radiation alone in patients with stage III and IV squamous cell carcinoma of the head and neck. Cancer 2000;88:876-883.
    • (2000) Cancer , vol.88 , pp. 876-883
    • Adelstein, D.1    Lavertu, P.2    Saxton, J.3
  • 53
    • 0035424059 scopus 로고    scopus 로고
    • Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy: Results of a multicentric randomized German trial in advanced head-and-neck cancer
    • Staar S, Rudat V, Stuetzer H et al. Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy: results of a multicentric randomized German trial in advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 2001;50:1161-1171.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , pp. 1161-1171
    • Staar, S.1    Rudat, V.2    Stuetzer, H.3
  • 54
    • 0037208591 scopus 로고    scopus 로고
    • An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patient with unresectable squamous cell head and neck cancer
    • Adelstein D, Li Y, Adams G et al. An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patient with unresectable squamous cell head and neck cancer J Clin Oncol 2003;21:92-98.
    • (2003) J Clin Oncol , vol.21 , pp. 92-98
    • Adelstein, D.1    Li, Y.2    Adams, G.3
  • 55
    • 3042701812 scopus 로고    scopus 로고
    • Final results of the 94-01 GORTEC randomized trial comparing radiotherapy alone to concomitant radiochemotherapy in advanced stage oropharynx carcinoma
    • Denis F, Garaud P, Bardet E et al. Final results of the 94-01 GORTEC randomized trial comparing radiotherapy alone to concomitant radiochemotherapy in advanced stage oropharynx carcinoma. J Clin Oncol 2004;22:69-76.
    • (2004) J Clin Oncol , vol.22 , pp. 69-76
    • Denis, F.1    Garaud, P.2    Bardet, E.3
  • 56
    • 9744239081 scopus 로고    scopus 로고
    • Update of MACH-NC (meta-analysis of chemotherapy in head & neck cancer) database focused on concomitant chemoradiotherapy
    • Bourhis J, Amand C, Pignon JP et al. Update of MACH-NC (meta-analysis of chemotherapy in head & neck cancer) database focused on concomitant chemoradiotherapy. Proc Am Soc Clin Oncol 2004;22:489s.
    • (2004) Proc Am Soc Clin Oncol , vol.22
    • Bourhis, J.1    Amand, C.2    Pignon, J.P.3
  • 58
    • 0038317889 scopus 로고    scopus 로고
    • Early morbidity after radiotherapy with or without chemotherapy in advanced head and neck cancer. Experience from four nonrandomized studies
    • Bieri S, Bentzen SM, Huguenin P et al. Early morbidity after radiotherapy with or without chemotherapy in advanced head and neck cancer. Experience from four nonrandomized studies. Strahlenther Onkol 2003;179:390-395.
    • (2003) Strahlenther Onkol , vol.179 , pp. 390-395
    • Bieri, S.1    Bentzen, S.M.2    Huguenin, P.3
  • 59
    • 2342656120 scopus 로고    scopus 로고
    • The need for adverse effects reporting standards in oncology clinical trials
    • Trotti A, Bentzen SM. The need for adverse effects reporting standards in oncology clinical trials. J Clin Oncol 2004;22:19-22.
    • (2004) J Clin Oncol , vol.22 , pp. 19-22
    • Trotti, A.1    Bentzen, S.M.2
  • 60
    • 17144463010 scopus 로고    scopus 로고
    • Postoperative concomitant irradiation and chemotherapy with mitomycin C and bleomycin for advanced head-and-neck carcinoma
    • Smid L, Budihna M, Zakotnik B et al. Postoperative concomitant irradiation and chemotherapy with mitomycin C and bleomycin for advanced head-and-neck carcinoma. Int J Radiat Oncol Biol Phys 2003;56:1055-1062.
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 1055-1062
    • Smid, L.1    Budihna, M.2    Zakotnik, B.3
  • 61
    • 10444220480 scopus 로고    scopus 로고
    • Cetuximab prolongs survival in patients with locoregionally advanced squamous cell carcinoma of head and neck: A phase III study of high dose radiation therapy with or without cetuximab
    • Bonner JA, Giralt J, Hirari PM et al. Cetuximab prolongs survival in patients with locoregionally advanced squamous cell carcinoma of head and neck: a phase III study of high dose radiation therapy with or without cetuximab. Proc Am Soc Clin Oncol 2004;22:5507.
    • (2004) Proc Am Soc Clin Oncol , vol.22 , pp. 5507
    • Bonner, J.A.1    Giralt, J.2    Hirari, P.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.