Expression of BCL-2 in liver grafts after adenoviral transfer improves survival following prolonged ischemia and reperfusion in rat liver transplantation

Transplantation Proceedings

Volumn 37, Issue 1, 2005, Pages 439-441

  Kienle, K ^a   Rentsch, M ^b   Muller T ^a   Engelhard, N ^a   Vogel, M ^a   Jauch, K W ^b   Beham, A ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; DOXYCYCLINE; DRINKING WATER; PROTEIN BCL 2; REPRESSOR PROTEIN; TETRACYCLINE; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOMEGALOVIRUS VECTOR; DRUG EFFECT; GRAFT SURVIVAL; IMMUNOHISTOLOGY; LIVER GRAFT; LIVER ISCHEMIA; LIVER TRANSPLANTATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; VIRUS INDUCTION; WESTERN BLOTTING;

EID: 16244368477     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2004.12.268     Document Type: Conference Paper

References (15)

1. G. Kroemer The proto-oncogene Bcl-2 and its role in regulating apoptosis Nat Med 3 1997 614
2. S. Natori, M. Selzner, K.L. Valentino Apoptosis of sinusoidal endothelial cells occurs during liver preservation injury by a caspase-dependent mechanism Transplantation 68 1999 89
3. M. Rentsch, A. Beham, I. Iesalnieks Impact of prolonged cold ischemia and reperfusion on apoptosis, activation of caspase 3, and expression of bax after liver transplantation in the rat Transplant Proc 33 2001 850
4. S.J. Korsmeyer, J.R. Shutter, D.J. Veis Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death Semin Cancer Biol 4 1993 327
5. N. Maulik, H. Sasaki, N. Galang Differential regulation of apoptosis by ischemia-reperfusion and ischemic adaptation Ann NY Acad Sci 874 1999 401
6. G. Bilbao, J.L. Contreras, D.E. Eckhoff Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene Ann Surg 230 1999 185
7. T.C. He, S. Zhou, Costa L.T. da A simplified system for generating recombinant adenoviruses Proc Natl Acad Sci USA 95 1998 2509
8. F.L. Graham, W.C. Russell, R. Nairn Characteristics of a human cell line transformed by DNA from human adenovirus type 5 J Gen Virol 36 1977 59
9. N., Kamada, CalneRY Orthotopic liver transplantation in the rat. Technique using cuff for portal vein anastomosis and biliary damage Transplantation 28 1979 47
10. W., Gao, J.J. Lemasters, R.G. Thurman Development of a new method for hepatic rearterialization in rat orthotopic liver transplantation. Reduction of liver injury and improvement of surgical outcome by arterialization Transplantation 19 1993 56
11. Mueller T, Kienle K, Beham A, et al. Caspase 3 inhibition improves survival and early graft function after ischemia and reperfusion in rat liver transplantation. Transplantation 78:1267, 2004
12. 2+ Oncogene 12 1996 2259
13. HockenberyDM, Z.N. Oltvai, X.M. Yin Bcl-2 functions in an antioxidant pathway to prevent apoptosis Cell 75 1993 241
14. Y. Tsujimoto, J. Cossman, E. Jaffe Involvement of the bcl-2 gene in human follicular lymphoma Science 228 1985 1440
15. E.J. Uhlmann, T. Subramanian, C.A. Vater A potent cell death activity associated with transient high level of BCL-2 J Biol Chem 273 1998 17926