Anticarcinogenic effect of 20(R)-ginsenoside Rg3 on induced hepatocellular carcinoma in rats

Journal of Sichuan University (Medical Science)

Volumn 36, Issue 2, 2005, Pages 217-220

  Li, Xiao ^a   Guan, Yong Song ^a   Zhou, Xiang Ping ^a   Sun, Long ^a   Liu, Yuan ^a   He, Qing ^a   Fu, Li ^a   Mao, Yong Qiu ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

20(R) ginsenoside Rg3; Apoptotsis; Hepatocellular carcinoma

Indexed keywords

CYCLINE; GINSENOSIDE; GINSENOSIDE RG 3; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; DIPLOIDY; DRUG EFFECT; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; RAT; TUMOR CELL; TUMOR VOLUME;

EID: 16244362737     PISSN: 1672173X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Liu WK, Xu SX, Che CT. Anti-proliferative effect of ginseng saponins on human prostate cancer cell line. Life Sci, 2000;67 (11):1297.
2. Keum YS, Han SS, Chun KS, et al. Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-kappaB activation and tumor promotion. Mutat-Res, 2003;5(23):523.
3. Ngio L, Pathmr C, Laiec S, et al. prognstic significance of proliferating cell nuclear antigen expression in hepatocellular carcinoma. Cancer, 1994;73(9):2268.
4. Zhang YW, Dou DQ, Zhang L, et al. Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions. Planta Med, 2001;67(5):417.
5. Kitagaawa I, Akedo H, Shinkai K, et al. Inhibition of tumor cell invasion and metasmasis by ginsenosis Rg3. Ginseng Rev, 1995;16(3):16.
6. Shinkai K, Akedo H, Mukai M, et al. Inhibition of in intro tumor cell invasion by ginsenoside Rg3. Jpn J Cancer Res, 1996;87(15):357.
7. Iishi H, Tatsuta M, Baba M, et al. Inhibition by ginsenoside Rg3 of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats. Clin Exp Metastasis, 1997;15(6):603.
8. Yun TK, Lee YS, Lee YH, et al. Anticarcinogenic effect of Panax ginseng C. A. Meyer and identification of active compounds. J Korean Med Sci, 2001;16(Suppl):S6.
9. Taniai M, Toimatsu M, Ckuda H. Immunohistochemical detection of proliferating nuclear antigen in hepatocellular carcinoma relationship to histological grade. J Gastroenterol Hepatol, 1993;8(2):420.
10. Wang D, Shi JQ, Liu FX. Immunochistochemical detection of proliferating cell nuclear antigen in hepatocellular carcinomas. China Natl J New Gastroenterol, 1997;3(2):101.