Can in vitro sensitivity of leukaemic cells to cytostatics influence clinical response of children with acute lymphoblastic leukaemia?;MUZE IN VITRO CITIVOST LEUKEMICKYCH BUNEK NA CYTOSTATIKA OVLIVNIT KLINICKOU ODPOVED DETI AKUTNI LYMFOBLASTICKOU LEUKEMII?

Cesko-Slovenska Pediatrie

Volumn 51, Issue 8, 1996, Pages 515-519

  Mihal V ^a   Hajduch M ^a   Stary J ^b   Sedlacek P ^b   Blazek B ^c   Michalek T ^a   Kotala, V ^a   Jabali, J ^d   Pospisilova D ^a   Klaskova E ^a   Safarova M ^a   Janost'akova A ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^c FN Ostrava   (Czech Republic)

^d LF UP a FN Olomouc   (Czech Republic)

Author keywords

Acute lymphoblastic leukaemia; In vitro drug resistance; Induction chemotherapy; LCS50; MTT assay; Protocol ALL BFM 90

Indexed keywords

ANTINEOPLASTIC AGENT; ASPARAGINASE; DAUNORUBICIN; METHOTREXATE; PREDNISOLONE; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CHILD; CLINICAL ARTICLE; DRUG RESPONSE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTRATHECAL DRUG ADMINISTRATION; LEUKEMIA CELL;

EID: 16044362706     PISSN: 00692328     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Farber, S., Diamond, L.K., Mercer, R.D., Sylvester, R.F.: Temporary remission in acute leukemia children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid (aminopterin). New Engl. J. Med., 238, 1948, s. 787 - 794.
2. Rivera, G.K., Pinkel, D., Simone, J.V., Hancock, M.L., Crist, W.M.: Treatment of acute lymphoblastic leukemia. 30-years experience at St. Jude Childrens Research Hospital. New Engl. J. Med., 329, 1993, s. 1290 - 1301.
3. Mihál, V., Hajdúch, M., Weigl, E., Videmanová, L., Šafářová, M.: Naše prvni zkušenosti s testováním citlivosti leukemických buněk na cytostatika. Čs. Pediat., 50, 1995, s. 195 - 200.
4. Pieters, R., Huismans, D.R., Loonen, A.H., Hahlen, K., van der Does-van den Berg, A., van Wering, E.R., Veerman, A.J.P.: Correlation of in vitro drug resistance assessed by the MTT assay with long-term clinical outcome in childhood acute lymphoblastic leukernia. In: Pieters, R.: Drug resistance in childhood leukemia, 1991, s. 103 - 117.
5. Hajdúch, M., Mihál, V., Minařík, J., Faber, E., Šafářová, M., Weigl, E., Antálek, P.: Decreased in vitro chemosensitivity of tumour cells in patients suffering from malignant diseases with poor prognosis. Cytotechnology, 18, 1996, s. 1 - 3.
6. Henze, G., Agthe, A.G., Neuendank, A., Hartmann, R., Dorffel, W., Bruhmuller, S., Klumper, E., Pieters, R., Veerman, A.J.P.: Tailored therapy for relapsed or refractory childhood acute lyraphoblastic leukemia. Leukemia, 9, 1995, s. 538.
7. Masson, E., Synold, T.W., Relling, M.W., Schuetz, J.D., Sandlund, J.T., Pui, C.H., Evans, W.E.: Allopurinol inhibits de novo purine synthesis in lymphoblasts of children with acute lymphoblastic leukemia. Leukemia, 10, 1996, s. 56 - 60.