J-104,123, a novel and orally-active inhibitor of squalene synthase: Stereoselective synthesis and cholesterol lowering effects in dogs

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 4, 1996, Pages 463-466

  Iwasawa, Yoshikazu ^a   Shibata, Jun ^a   Mitsuya, Morihiro ^a   Masaki, Hitoshi ^a   Hayashi, Masahiro ^a   Kanno, Tetsuya ^a   Sawasaki, Yoshio ^a   Hisaka, Akihiro ^a   Kamei, Toshio ^a   Tomimoto, Koji ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILIPEMIC AGENT; CHOLESTEROL; ENZYME INHIBITOR; J 104118; J 104123; SQUALENE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DOG; DRUG SYNTHESIS; ENZYME INHIBITION; HEP 2 CELL; NONHUMAN; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 16044362193     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00033-9     Document Type: Article

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