Norepinephrine as mediator in the stimulation of phagocytosis induced by moderate exercise

European Journal of Applied Physiology

Volumn 93, Issue 5-6, 2005, Pages 714-718

  Ortega, E ^a   Marchena, J M ^a   Garcia J J ^a   Barriga, C ^a   Rodriguez A B ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

Author keywords

Exercise stress; Immunology; Neutrophils; Norepinephrine; Phagocytosis

Indexed keywords

ADRENALIN; CALCIUM; CYCLIC AMP; CYCLIC GMP; HYDROCORTISONE; NORADRENALIN; PHENTOLAMINE; PROPRANOLOL;

ADRENALIN BLOOD LEVEL; ADULT; ARTICLE; BASAL METABOLIC RATE; CANDIDA ALBICANS; CELL STIMULATION; CONTROLLED STUDY; CULTURE MEDIUM; ENERGY RECOVERY; EXERCISE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; LIFESTYLE; MALE; NEUROENDOCRINE SYSTEM; NEUTROPHIL; NONHUMAN; NORADRENALIN BLOOD LEVEL; NORMAL HUMAN; OXYGEN CONSUMPTION; PHAGOCYTOSIS; PRIORITY JOURNAL;

ADULT; CANDIDA ALBICANS; CELL CULTURE TECHNIQUES; EXERCISE; HUMANS; IMMUNE SYSTEM; MALE; NEUTROPHILS; NOREPINEPHRINE; PHAGOCYTOSIS;

EID: 15944400378     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-004-1245-8     Document Type: Article

References (25)

1. Alteraifi AM, Zhelev DV (1997) Transient increase of free cytosolic calcium during neutrophil motility responses. J Cell Sci 110:1967-1977 1:CAS:528:DyaK2sXlvVaqtrk%3D
2. Blannin AK, Chatwin LJ, Cave R, Gleeson M (1996) Effects of submaximal cycling and long-term endurance training on neutrophil phagocytic activity in middle aged men. Br J Sports Med 30:125-129 1:STN:280:BymA1M3otVw%3D
3. Brenner I, Shek PN, Zamecnik J, Shephard RJ (1998) Stress hormones and the immunological responses to heat and exercise. Int J Sports Med 19:130-143 1:CAS:528:DyaK1cXhvF2ru7Y%3D
4. Coffey RG (1992) Effects of cyclic nucleotides on granulocytes. Immunol Ser 57:301-338 1:CAS:528:DyaK3sXisFaksLk%3D
5. Fitzgerald L (1998) Exercise and the immune system. Immunol Today 9:337-339 10.1016/0167-5699(88)91332-1
6. Forner MA, Barriga C, Rodríguez AB, Ortega E (1995) A study of the role of corticosterone as a mediator in exercise-induced stimulation of murine macrophage phagocytosis. J Physiol (Lond) 488:789-794
7. García JJ, Sáez MC, De la Fuente M, Ortega E (2003) Regulation of phagocytic process of macrophages by norepinephrine and its end metabolite 4-hydroxy-3-metoxyphenyl-glycol. Role of α- and β-adrenoreceptors. Mol Cell Biochem 254:299-304 10.1023/ A:1027345820519
8. Hack V, Strobel G, Weiss M, Weicker H (1994) PMN cell counts and phagocytic activity of highly trained athletes depend on training period. J Appl Physiol 77:1731-1735 1:STN:280:ByqC3sjptFM%3D
9. Hoffman-Goetz L, Pedersen BK (1994) Exercise and the immune system: A model of the stress response? Immunol Today 15:382-387 10.1016/ 0167-5699(94)90177-5
10. Krause R, Patruta S, Daxbock F, Fladerer P, Biegelmayer C, Wenisch C (2001) Effect of vitamin C on neutrophil function after high-intensity exercise. Eur J Clin Invest 3:258-263 10.1046/j.1365-2362.2001.00797.x
11. Nagatomi R, Kaifu T, Okutsu M, Zhang X, Kanemi O, Ohmori H (2000) Modulation of the immune system by the autonomic nervous system and its implication in immunological changes after training. Exerc Immunol Rev 6:54-74 1:STN:280:DC%2BD3M%2FjtVKgtQ%3D%3D
12. Ortega E (1994) Influence of exercise on phagocytosis. Int J Sports Med 15:S172-S178 7883400
13. Ortega E (2003) Neuroendocrine mediators in the modulation of phagocytosis by exercise: Physiological implications. Exerc Immunol Rev 9:70-93 14686096
14. Ortega E, Collazos ME, Maynar M, Barriga C, De la Fuente M (1993) Stimulation of the phagocytic function of neutrophils in sedentary men after acute moderate exercise. Eur J Appl Physiol 66:60-64 1:STN:280:ByyC2crpt1w%3D
15. Ortega E, García JJ, Sáez MC, De la Fuente M (2000) Changes with aging in the modulation of macrophages by norepinephrine. Mech Ageing Dev 118:103-14 10.1016/S0047-6374(00)00160-3
16. Peake JM (2002) Exercise-induced alterations in neutrophil degranulation and respiratory burst activity: Possible mechanism of action. Exerc Immunol Rev 8:49-100 12690938
17. Pedersen BK, Hoffman-Goetz L (2000) Exercise and the immune system: regulation, integration, and adaptation. Physiol Rev 80:1055-1081 1:CAS:528:DC%2BD3cXlsFWjsLc%3D
18. Pedersen BK, Bruunsgaard H, Klokker M, Kappel M, MacLean DA, Nielsen HB, Rohde T, Ullum H, Zacho M (1997) Exercise-induced immunomodulation-possible roles of neuroendocrine and metabolic factors. Int J Med 18:S2-S7 1:CAS:528:DyaK2sXjs1CqsL4%3D
19. Pedersen BK, Rohde T, Ostrowski K (1998) Recovery of the immune system after exercise. Acta Physiol Scand 162:325-332 10.1046/ j.1365-201X.1998.0325e.x
20. i in single cells. Prog Clin Biol Res 210:53-56 1:CAS:528:DyaL28XitVehsL4%3D
21. Pyne DB, Smith JA, Baker MS, Telford RD, Weidemann MJ (2000) Neutrophil oxidative activity is differentially affected by exercise intensity and type. J Sci Med Sport 3:44-54 1:STN:280:DC%2BD3cvhvFSisw%3D%3D
22. Titinger GR, Theron AJ, Anderson R, Ker JA (2001) The anti-inflammatory interactions of epinephrine with human neutrophils in vitro are achieved by AMP-mediated accelerated requestration of cytosolic calcium. Biochem Pharmacol 61:1319-1328 10.1016/S0006-2952(01)00588-3
23. Weiss M, Schneider EM, Tarnow J, Mettler S, Krone M, Teschemacher A, Lemoine H (1996) Is inhibition of oxygen radical production of neutrophils by sympathomimetics mediated via beta-2 adrenoceptors? J Pharmacol Exp Ther 278:1105-1113 1:CAS:528:DyaK28XmtVSjtrs%3D
24. Ydrenius L, Majeed M, Rasmusson BJ, Stendahl O, Sarndahl E (2000) Activation of cAMP-dependent protein kinase is necessary for actin rearrangements in human neutrophils during phagocytosis J Leuk Biol 67:520-528
25. Zalavary S, Stendahl O, Bengtsson T (1994) The role of cyclic AMP, calcium and filamentous actin in adenosine modulation of Fc receptor-mediated phagocytosis in human neutrophils. Biochim Biophys Acta 1222:249-256 10.1016/0167-4889(94)90176-7