Intrathecal epinephrine in combined spinal-epidural analgesia for labor: Dose-response relationship for epinephrine added to a local anesthetic-opioid combination

International Journal of Obstetric Anesthesia

Volumn 14, Issue 2, 2005, Pages 121-125

  Gurbet, A ^a   Turker, G ^a   Kose, D O ^a   Uckunkaya, N ^a  

^a ULUDAG UNIVERSITY   (Turkey)

Author keywords

Combined spinal epidural; Epinephrine; Labor analgesia

Indexed keywords

ADRENALIN; ANESTHETIC AGENT; BUPIVACAINE; EPHEDRINE; FENTANYL; OPIATE; OXYTOCIN;

ADULT; APGAR SCORE; ARTICLE; CHILDBIRTH; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; EPIDURAL ANESTHESIA; FEMALE; FETUS; FETUS HEART RATE; GESTATIONAL AGE; HEART RATE; HUMAN; HYPOTENSION; LABOR; LOCAL ANESTHESIA; MAJOR CLINICAL STUDY; MEAN ARTERIAL PRESSURE; MOTOR NERVE BLOCK; NAUSEA; NERVE BLOCK; OBSTETRIC ANESTHESIA; PAIN ASSESSMENT; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SPINAL ANESTHESIA; VOMITING;

EID: 15944396415     PISSN: 0959289X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijoa.2004.12.002     Document Type: Article

References (17)

1. C. Mardirosoff, and L. Dumont Two doses of intrathecal sufentanil combined with bupivacaine and epinephrine for labor analgesia Anesth Analg 89 1999 1263 1266
2. M.D. Owen, O. Ozsarac, S. Sahin, N. Uckunkaya, N. Kaplan, and I. Magunaci Low-dose clonidine and neostigmine prolong the duration of intrathecal bupivacaine-fentanyl for labor analgesia Anesthesiology 92 2000 361 366
3. T. Okutomi, J. Mochizuki, K. Amano, and S. Datta The effect of intrathecal epinephrine on epidural infused analgesics during labor Reg Anesth Pain Med 28 2003 108 112
4. P.E. Gautier, M. De Kock, L. Fanard, A. Van Steenberge, and J.L. Hody Intrathecal clonidine combined with sufentanil for labor analgesia Anesthesiology 88 1998 651 656
5. J.G. Klamt, A. Slullitel, I.V. Garcia, and W.A. Prado Postoperative analgesic effect of intrathecal neostigmine and its influence on spinal anesthesia Anesth Analg 82 1996 617 620
6. D.C. Campbell, R. Banner, L.A. Crone, W. Gore-Hickman, and R.W. Yip Addition of epinephrine to intrathecal bupivacaine and sufentanil for ambulatory labor analgesia Anesthesiology 86 1997 525 531
7. P.E. Gautier, F. Debry, L. Fanard, A. Van Steenberge, and J.L. Hody Ambulatory combined spinal-epidural analgesia for labor: influence of epinephrine on bupivacaine-sufentanil combination Reg Anesth 22 1997 143 149
8. J.G. Collins, L.M. Kitahata, E. Homma, and M. Suzukawa Spinal cord effects of epinephrine Anesth Analg 60 1981 913 914
9. R. Kozody, R.J. Palahniuk, J.G. Wade, M.O. Cumming, and W.R. Pucci The effect of subarachnoid epinephrine and phenylephrine on spinal cord blood flow Can Anaesth Soc J 31 1984 503 508
10. S.S. Porter, M.S. Albin, W.A. Watson, L. Bunegin, and G. Pantoja Spinal cord and cerebral blood flow responses to subarachnoid injection of local anesthetics with and without epinephrine Acta Anaesthesiol Scand 29 1985 330 338
11. J.G. Collins, L.M. Kitahata, H.E. Matumoto, and M. Suzukawa Spinally administered epinephrine suppresses noxiously evoked activity of WDR neurons in dorsal horn of spinal cord Anesthesiology 60 1984 269 275
12. S.V.R. Reddy, J.L. Maderdrut, and T.L. Yaksh Spinal cord pharmacology of adrenergic agonist-mediated antinociception J Pharmacol Exp Ther 213 1980 525 533
13. T.L. Yaksh, and S.V.R. Reddy Studies in the primate on the analgesic effects associated with intrathecal actions of opiates α-adrenergic agonists and baclofen Anesthesiology 54 1981 451 467
14. A.M. Malinow, B.L.K. Mokriski, and M.K. Nomura Effect of epinephrine on intrathecal fentanyl analgesia in patients undergoing postpartum tubal ligation Anesthesiology 73 1990 381 385
15. W.M. Grieco, M.C. Norris, and B.L. Leighton Intrathecal sufentanil for labor analgesia: the effect of adding morphine or epinephrine Anesth Analg 77 1993 1149 1154
16. W.R. Camann, B.H. Minzter, R.A. Denney, and S. Datta Intrathecal sufentanil for labor analgesia: effects of added epinephrine Anesthesiology 78 1993 870 874
17. T.F. Meert, and M. De Kock Interactions between the lipophilic opioid sufentanil and clonidine in rats after spinal application Acta Anaesthesiol Scand 39 1995 528 535