In vivo killing of Giardia trophozoites harbouring bacterial endosymbionts by intestinal Paneth cells: An ultrastructural study

Parasitology

Volumn 130, Issue 3, 2005, Pages 269-274

  El Shewy, K A ^a,c   Eid, R A ^b  

^a Suez Canal University Faculty of Medicine   (Egypt)

^b Zagazig University   (Egypt)

^c KING KHALID UNIVERSITY   (Saudi Arabia)

Author keywords

Electron microscopy; Endosymbiosis; Giardiasis; in vivo killing; Naturally infected mice; Paneth cells

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGENICITY; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ENDOSYMBIONT; GIARDIA; GIARDIA MURIS; HOST PARASITE INTERACTION; HOST RANGE; IN VIVO STUDY; INFECTION; MOUSE; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; TROPHOZOITE;

ANIMALS; GIARDIA; GIARDIASIS; HOST-PARASITE RELATIONS; MICE; PANETH CELLS; SYMBIOSIS;

BACTERIA (MICROORGANISMS); GIARDIA; PROTOZOA;

EID: 15944386264     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0031182004006547     Document Type: Article

References (12)

1. ALEY, S. B., ZIMMERMAN, M., HETSKO, M., SELSTED, M. E. & GILLIN, F. D. (1994). Killing of Giardia lamblia by cryptdins and cationic neutrophils peptides. Infection and Immunity 62, 5397-5403.
2. AYABE, T., SATCHELL, D. P., WILLSON, C. L., PARKS, W. C., SELSTED, M. E. & OUELLETTE, A. J. (2000). Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria. Nature, Immunology 1, 113-138.
3. DE-SOUZA, W. & MOTTA, M. C. (1999). Endosymbiosis in protozoa of Trypanosomatidae family. FEMS Microbiology Letters 173, 1-8.
4. GLAUERT, A. M. (1980). Fixation, Dehydration and Embedding of Biological Specimens. 3rd Edn. North-Holland Publishing, Amsterdam.
5. JONES, D. E. & BEVINS, C. L. (1992). Paneth cells in the human small intestine express an antimicrobial peptide gene. Journal of Biological Chemistry 267, 23216-23225.
6. MARTIN, E., GANZ, T. & LEHRER, R. I. (1995). Defensins and other endogenous peptide antibiotics of vertebrates. Journal of Leukocyte Biology 58, 128-136.
7. MENG, T. C., HETSKO, M. L. & GILLIN, F. D. (1993). Antigenic switching of TSA 417, a trophozoite surface protein, following of the life cycle of Giardia lamblia. Infection and Immunity 61, 5394-5397.
8. MEYER, E. A. (1990). Taxonomy and nomenclature. In Giardiasis (ed. Meyer, E. A.), pp. 51-60. Elsevier, Amsterdam.
9. NEMANIC, P. C., OWEN, R. L., STEVENS, D. P. & MULLER, J. C. (1979). Ultrastructural observations on giardiasis in a mouse model. II. Endosymbiosis and organelle distribution in Giardia muris and Giardia lamblia. Journal of Infectious Diseases 140, 222-228.
10. OUELLETTE, A. J. & SELSTED, M. E. (1996). Paneth cell defensins: Endogenous peptide components of intestinal host defense. FASEB Journal 10, 1280-1289.
11. ROBERTS-THOMSON, I. C., STEVENS, D.P. & MAHMMOUD, A. A. F. (1976). Giardia in mouse: an animal model. Gastroenterology 71, 57.
12. SELSTED, M. E., MILLER, S. I., MENSCHEN, A. H. & OUELLETTE, A. J. (1992). Enteric defensins: antibiotic peptide component of intestinal host defense. Journal of Cell Biology 118, 929-939.