Decreased connexin 43 expression correlated with eosinophil infiltration in nasal polyps

American Journal of Rhinology

Volumn 19, Issue 1, 2005, Pages 59-64

  Yeh, Te Huei ^a   Hsu, Wei Chung ^a   Chen, Yuh Shyan ^a   Hsu, C J Chuan Jen ^a   Lee, Shiann Yann ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 43;

ADULT; AGED; ARTICLE; CELL DENSITY; CELL STRUCTURE; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORRELATION ANALYSIS; EOSINOPHIL; FACIAL BONE; FEMALE; FIBROBLAST; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; NEUTROPHIL CHEMOTAXIS; NOSE POLYP; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

EID: 15944385338     PISSN: 10506586     EISSN: None     Source Type: Journal    
DOI: 10.1177/194589240501900110     Document Type: Article

References (20)

1. Pawankar R. Nasal polyposis: An update. Curr Opin Allergy Clin Immunol 3:1-6, 2003.
2. Nonaka M, Pawankar R, Saji F, and Yagi T. Distinct expression of RANTES and GM-CSF by lipopolysaccharide in human nasal fibroblasts but not in other airway fibroblasts. Int Arch Allergy Immunol 119:314-321, 1999.
3. Shin SH, Lee SH, Jeong HS, and Kita H. The effect of nasal polyp epithelial cells on eosinophil activation. Laryngoscope 113:1374-1377, 2003.
4. Kramer MF, Ostertag P, Pfrogner E, et al. Nasal Interleukin-5, immunoglobulin E, eosinophilic cationic protein, and soluble intercellular adhesion molecule-1 in chronic sinusitis, allergic rhinitis, and nasal polypoisi. Laryngoscope 110:1056-1062, 2000.
5. Saji F, Nonaka M, and Pawankar R. Expression of RANTES by IL-1 beta and TNF-alpha stimulated nasal polyp fibroblasts. Auris Nasus Larynx 27:247-252, 2000.
6. Bachert C, Gevaert P, Holtappels G, et al. Total and specific IgE in nasal polyps is related to local eosinophil inflammation. J Allergy Clin Immunol 107:607-614, 2001.
7. Jahnsen FL, Haraldsen G, Aanesen JP, et al. Eosinophil infiltration is related to increased expression of vascular cell adhesion molecule-1 in nasal polyps. Am J Respir Cell Mol Biol 12:624-632, 1995.
8. Sabatinit F, Silvestri M, Sale R, et al. Fibroblast-eosinophil interaction. Modulation of adhesion molecules expression and chemokine release by human fetal lung fibroblasts in response to IL-4 and TNF-α. Immunol Lett 84:173-178, 2002.
9. Yeh TH, Su MC, Hsu CJ, et al. Epithelial cells of nasal mucosa express functional gap junctions of connexin 43. Acta Otolaryngol (Stockh) 123:314-320, 2003.
10. Kumar NM, and Gilula NB. The gap junction communication channel. Cell 84:381-388, 1996.
11. Nakagawa T, Yamane H, Nakai Y, et al. Comparative assessment of cell proliferation and accumulation of extracellular matrix in nasal polyps. Acta Otolaryngol (Stockh) Suppl 538:205-208, 1998.
12. Guo Y, Martinez-Williams C, Yellowley CE, et al. Connexin expression by alveolar epithelial cells is regulated by extracellular matrix. Am J Physiol Lung Cell Mol Physiol 280:L191-L202, 2001.
13. Sanson M, Marcoud V, Robin E, et al. Connexin 43-mediated bystander effect in two rat glioma cell models. Cancer Gene Ther 9:149-155, 2002.
14. Goldberg GS, Bechberger JF, Tajima Y, et al. Connexin43 suppressed MFG-E8 while inducing contact growth inhibition of glioma cells. Cancer Res 60:6018-6026, 2000.
15. King TJ, Fukushima LH, Yasui Y, et al. Inducible expression of the gap junction protein connexin43 decreases the neoplastic potential of HT-1080 human fibrosarcoma cells in vitro and in vivo. Mol Carcinog 35:29-41, 2002.
16. Redington AE, and Howarth PH. Airway wall remodelling in asthma. Thorax 52:310-312, 1997.
17. Besancon-Watelet C, Bene MC, Montagne P, et al. Eosinophilia and cell activation mediators in nasal secretions. Laryngoscope. 112:43-46, 2002.
18. Moyer KE, Saggers GC, Allison GM, et al. Effects of interleukin-8 on granulation tissue maturation. J Cell Physiol. 193:173-179, 2002.
19. Lechapt-Zalcman E, Coste A, d'Ortho MP, et al. Increased expression of matrix metalloproteinase-9 in nasal polyps. J Pathol 193:233-241, 2001.
20. Liu CM, Hong CY, Shun CT, et al. Matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 gene expressions and their differential regulation by proinflammatory cytokines and prostaglandin in nasal polyp fibroblasts. Ann Otol Rhinol Laryngol 110:1129-1136, 2001.