How tightly can a drug be bound to a protein and still be removable by charcoal hemoperfusion in overdose cases?

Journal of Toxicology - Clinical Toxicology

Volumn 43, Issue 2, 2005, Pages 95-99

  Kawasaki, Chiyo I ^a,c   Nishi, Reiko ^a   Uekihara, Souichi ^a   Hayano, Syunichi ^a   Kragh Hansen, Ulrich ^b   Otagiri, Masaki ^c  

^a JAPANESE RED CROSS KUMAMOTO HOSPITAL   (Japan)

^b AARHUS UNIVERSITY   (Denmark)

^c KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Charcoal hemoperfusion; Overdose; Protein binding

Indexed keywords

ALPRAZOLAM; AMITRIPTYLINE; AMOBARBITAL; APRONAL; BROMAZEPAM; BROMISOVAL; BROTIZOLAM; CHARCOAL; CHLORPROMAZINE; DIPHENHYDRAMINE; ETIZOLAM; FLUNITRAZEPAM; HALOPERIDOL; IMIPRAMINE; MIANSERIN; NITRAZEPAM; PHENOBARBITAL; PLASMA PROTEIN; PROMETHAZINE; THEOPHYLLINE; THIORIDAZINE; TRIAZOLAM; ACTIVATED CARBON;

ARTICLE; CALCULATION; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG OVERDOSE; DRUG PROTEIN BINDING; EXTRACORPOREAL CIRCULATION; HEMOPERFUSION; HUMAN; JAPAN; TREATMENT OUTCOME; BINDING AFFINITY; DRUG ADSORPTION; HOSPITAL; IN VITRO STUDY;

ADSORPTION; CHARCOAL; HEMOPERFUSION; HUMANS; JAPAN; OROSOMUCOID; OVERDOSE; PHARMACEUTICAL PREPARATIONS; POISONING; PROTEIN BINDING; SERUM ALBUMIN;

EID: 15944381174     PISSN: 07313810     EISSN: None     Source Type: Journal    
DOI: 10.1081/CLT-200050426     Document Type: Article

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