Low dose diamorphine reduces breathlessness without causing a fall in oxygen saturation in elderly patients with end-stage idiopathic pulmonary fibrosis

Palliative Medicine

Volumn 19, Issue 2, 2005, Pages 128-130

  Allen, Stephen C ^a   Raut, Satru ^b   Woollard, Jane ^b   Vassallo, Michael ^b  

^a BOURNEMOUTH UNIVERSITY   (United Kingdom)

^b POOLE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Diamorphine; Dyspnoea; Elderly; Idiopathic pulmonary fibrosis

Indexed keywords

DIAMORPHINE; MORPHINE; OXYGEN;

AGED; ARTICLE; BREATHING RATE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DYSPNEA; ELDERLY CARE; FEMALE; FOLLOW UP; HEART RATE; HUMAN; IDIOPATHIC DISEASE; LOW DRUG DOSE; LUNG FIBROSIS; MALE; OXYGEN SATURATION; PATIENT REFERRAL; RESPIRATION DEPRESSION; SYSTOLIC BLOOD PRESSURE; VISUAL ANALOG SCALE;

ACUTE DISEASE; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; DYSPNEA; FEMALE; HUMANS; MALE; MORPHINE; PULMONARY FIBROSIS;

EID: 15944379648     PISSN: 02692163     EISSN: None     Source Type: Journal    
DOI: 10.1191/0269216305pm998oa     Document Type: Article

References (11)

1. Araki T, Katsura H, Sawabe M et al. A clinical study of idiopathic pulmonary fibrosis based on autopsy studies in elderly patients. Intern Med 2003; 42: 483-89.
2. Webb M, Moody LE, Mason LA. Dyspnoea assessment and management in hospice patients with pulmonary disorders. Am J Hosp Palliat Care 2000; 17: 259-64.
3. Higginson I, McCarthy M. Measuring symptoms in terminal cancer: are pain and dyspnoea controlled? J Roy Soc Med 1989; 82 264-67.
4. O'Driscoll M, Corner J, Bailey C. The experience of breathlessness in lung cancer. Eur J Cancer Care (Engl) 1999; 8 37-43.
5. Ripamonti C. Management of dyspnoea in advanced cancer patients. Support Cancer Care 1999; 7: 233-43.
6. Harris-Eze A, Sridhar G, Clemens RE et al. Low-dose nebulized morphine does not improve exercise in interstitial lung disease. Am J Respir Crit Care Med 1995; 152: 1940-45.
7. Brack T, Jubran A, Tobin MJ. Dyspnoea and decreased variability of breathing in patients with restrictive lung disease. Am J Respir Crit Care Med 2002; 165: 1260-64.
8. Muers MF. Opioids for dyspnoea. Thorax 2002; 57: 922-23.
9. Jennings A-L, Davies AN, Higgins JPT et al. A systematic review of the use of opioids in the management of dyspnoea. Thorax 2002; 57: 939-44.
10. Abernethy AP, Currow DC, Frith P et al. Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. Brit Med J 2003; 327: 523-26.
11. Jennings AL, Davies AN, Higgins JP, Broadley K. Opioids for the palliation of breathlessness in terminal illness. Cochrane Database Syst Rev 2001; 4: CD002066.