Glutathione metabolism in rat cardiac tissues in acute doxorubicin-induced intoxication

Voprosy Onkologii

Volumn 51, Issue 1, 2005, Pages 108-112

  Glushkov, S I ^a   Kutsenko, S A ^a   Novikova, T M ^a   Axenov, V V ^b  

^a S M Kirov Military Medical Academy   (Russian Federation)

^b ZPSolovyev Reg Mil Clin H   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; OXIDOREDUCTASE;

ACUTE TOXICITY; ALBINISM; ARTICLE; BIOCHEMISTRY; CARDIOTOXICITY; CONCENTRATION RESPONSE; DATA ANALYSIS; GLUTATHIONE METABOLISM; HEART; NONHUMAN;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; MALE; MYOCARDIUM; RATS;

EID: 15944376915     PISSN: 05073758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Bellomo G., Thor H., Orrenius S. Modulation of cellular glutathione and protein thiol status during quinone metabolism // Meth. Enzymol. - 1990. - Vol. 186. - P. 627-635.
2. Carlberg I., Mannervik B. Glutathione reductase // Meth. Enzymol. - 1985. - Vol. 113. - P. 484-490.
3. De Almeida A.F., Curi R., Newsholme P. Maximal activities of key enzymes of glutaminolysis, glycolysis, Krebs cycle and pentose-phosphate pathway of several tissues in mature and aged rats //Int. J. Biochem. - 1989. - Vol. 21, No 8. - P. 937-940.
4. Ellman G.L. Tissue sulfhydryl groups // Arch. Biochem. Biophys. - 1959. - Vol. 82, No 1. - P. 70-77.
5. Gessner T., Vaughan L.A., Beehler B.C. et al. Elevated pentose cycle and glucuronyltransferase in daunorubicin-resistant P388 cells // Cancer Res. - 1990. - Vol. 50, No 13. - P. 3921-3927.
6. Gewirtz D.A. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin // Biochem. Pharmacol. - 1999. - Vol. 57, No 7. - P. 727-741.
7. Habig W.H., Jakoby W.B. Assay for differentiation of glutathione S-transferases // Meth. Enzymol. - 1981. - Vol. 77. - P. 398-405.
8. Kornberg A., Horecker B.L., Smyrniot P.Z. Glucose-6-phosphate dehydrogenase-6-phosphogluconic dehydrogenase // Meth. Enzymol. - 1955. - Vol. 1. - P. 323-327.
9. Lown J.W. The chemistry of DNA damage by antitumor drugs // Molecular Aspects of Anticancer Drug Aaction/ Eds. S.Niedle, M.Waring. - London: Mac Millan Press, 1983. - P. 283-314.
10. Peterson G.L. Simplification of protein assay method of Lowry et al - which is more generally applicable? // Anal. Biochem. - 1977. - Vol. 83, No 2. - P. 346-356.
11. Powell S.R., Chevion M. The effect of chronic administration of doxorubicin on the rat cardiac and hepatic glutathione redox system // Res. Commun. Chem. Pathol. Pharmacol. - 1991. - Vol. 74, No 3. - P. 273-286.
12. Uchiyama M , Michara M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test // Anal. Biochem. - 1978. - Vol. 86, No 1. - P. 271-278.