메뉴 건너뛰기




Volumn 19, Issue 3, 2005, Pages 223-234

Transgenic overexpression of interleukin-1 receptor antagonist in the CNS influences behaviour, serum corticosterone and brain monoamines

Author keywords

Anti inflammatory; Anxiety; Cytokines; Dopamine; Motor activity; Mouse; Serotonin

Indexed keywords

BRAIN MONOAMINE; CORTICOSTERONE; DOPAMINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SEROTONIN; IL1RN PROTEIN, HUMAN; IL1RN PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR; SIALOGLYCOPROTEIN;

EID: 15944370521     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2004.07.006     Document Type: Article
Times cited : (26)

References (59)
  • 1
    • 0028181158 scopus 로고
    • Interleukin-1β stimulates tyrosine hydroxylase activity in the median eminence
    • P. Abreu, E. Llorente, M.M. Hernandez, and M.C. Gonzalez Interleukin-1β stimulates tyrosine hydroxylase activity in the median eminence Neuroreport 5 1994 1356 1358
    • (1994) Neuroreport , vol.5 , pp. 1356-1358
    • Abreu, P.1    Llorente, E.2    Hernandez, M.M.3    Gonzalez, M.C.4
  • 3
    • 0142172107 scopus 로고    scopus 로고
    • Impaired interleukin-1 signalling is associated with deficits in hippocampal memory processes and neural plasticity
    • A. Avital, I. Goshen, A. Kamsler, M. Segal, K. Iverfeldt, G. Richter-Levin, and R. Yirmiya Impaired interleukin-1 signalling is associated with deficits in hippocampal memory processes and neural plasticity Hippocampus 13 2003 826 834
    • (2003) Hippocampus , vol.13 , pp. 826-834
    • Avital, A.1    Goshen, I.2    Kamsler, A.3    Segal, M.4    Iverfeldt, K.5    Richter-Levin, G.6    Yirmiya, R.7
  • 4
    • 0032858323 scopus 로고    scopus 로고
    • Cytokines inhibit sexual behavior in female rats: II. Prostaglandins mediate the suppressive effects of interleukin-1β
    • R. Avitsur, J. Weidenfeld, and R. Yirmiya Cytokines inhibit sexual behavior in female rats: II. Prostaglandins mediate the suppressive effects of interleukin-1β Brain Behav. Immun. 13 1999 33 45
    • (1999) Brain Behav. Immun. , vol.13 , pp. 33-45
    • Avitsur, R.1    Weidenfeld, J.2    Yirmiya, R.3
  • 6
    • 0022530255 scopus 로고
    • Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones
    • H.O. Besedovsky, A. del Rey, E. Sorkin, and C.A. Dinarello Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones Science 233 1986 652 654
    • (1986) Science , vol.233 , pp. 652-654
    • Besedovsky, H.O.1    Del Rey, A.2    Sorkin, E.3    Dinarello, C.A.4
  • 7
    • 0026599095 scopus 로고
    • Effects of interleukin-1 receptor antagonist on the behavioural effects of lipopolysaccharide in rat
    • R.M. Bluthe, R. Dantzer, and K.W. Kelley Effects of interleukin-1 receptor antagonist on the behavioural effects of lipopolysaccharide in rat Brain Res. 573 1992 318 320
    • (1992) Brain Res. , vol.573 , pp. 318-320
    • Bluthe, R.M.1    Dantzer, R.2    Kelley, K.W.3
  • 8
    • 0042661152 scopus 로고    scopus 로고
    • Low doses of interleukin-1β improve the leverpress avoidance performance of Sprague-Dawley rats
    • F.X. Brennan, K.D. Beck, and R.J. Servatius Low doses of interleukin-1β improve the leverpress avoidance performance of Sprague-Dawley rats Neurobiol. Learn. Mem. 80 2003 168 171
    • (2003) Neurobiol. Learn. Mem. , vol.80 , pp. 168-171
    • Brennan, F.X.1    Beck, K.D.2    Servatius, R.J.3
  • 9
    • 0028606921 scopus 로고
    • Behavioral habituation to spatial novelty: Interference and noninterference studies
    • A. Cerbone, and A.G. Sadile Behavioral habituation to spatial novelty: interference and noninterference studies Neurosci. Biobehav. Rev. 18 1994 497 518
    • (1994) Neurosci. Biobehav. Rev. , vol.18 , pp. 497-518
    • Cerbone, A.1    Sadile, A.G.2
  • 10
    • 0032571740 scopus 로고    scopus 로고
    • Behavioral effects of peripheral interleukin-1 administration in adult CD-1 mice: Specific inhibition of the offensive components of intermale agonistic behavior
    • F. Cirulli, L. De Acetis, and E. Alleva Behavioral effects of peripheral interleukin-1 administration in adult CD-1 mice: specific inhibition of the offensive components of intermale agonistic behavior Brain Res. 791 1998 308 312
    • (1998) Brain Res. , vol.791 , pp. 308-312
    • Cirulli, F.1    De Acetis, L.2    Alleva, E.3
  • 12
    • 17144449436 scopus 로고    scopus 로고
    • An assessment of the effects of central interleukin-1β, -2, -6, and tumor necrosis factor-α administration on some behavioural, neurochemical, endocrine and immune parameters in the rat
    • T.J. Connor, C. Song, B.E. Leonard, Z. Merali, and H. Anisman An assessment of the effects of central interleukin-1β, -2, -6, and tumor necrosis factor-α administration on some behavioural, neurochemical, endocrine and immune parameters in the rat Neuroscience 84 1998 923 933
    • (1998) Neuroscience , vol.84 , pp. 923-933
    • Connor, T.J.1    Song, C.2    Leonard, B.E.3    Merali, Z.4    Anisman, H.5
  • 13
    • 0026021352 scopus 로고
    • Behavioural effects of peripherally injected interleukin-1: Role of prostaglandins
    • F. Crestani, F. Seguy, and R. Dantzer Behavioural effects of peripherally injected interleukin-1: role of prostaglandins Brain Res. 542 1991 330 335
    • (1991) Brain Res. , vol.542 , pp. 330-335
    • Crestani, F.1    Seguy, F.2    Dantzer, R.3
  • 14
    • 0035165407 scopus 로고    scopus 로고
    • Cytokine-induced sickness behavior: Where do we stand?
    • R. Dantzer Cytokine-induced sickness behavior: where do we stand? Brain Behav. Immun. 15 2001 7 24
    • (2001) Brain Behav. Immun. , vol.15 , pp. 7-24
    • Dantzer, R.1
  • 15
    • 0025006732 scopus 로고
    • Interleukin-1 affects the behavioural despair response in rats by an indirect mechanism which requires endogenous CRF
    • S. del Cerro, and J. Borrell Interleukin-1 affects the behavioural despair response in rats by an indirect mechanism which requires endogenous CRF Brain Res. 528 1990 162 164
    • (1990) Brain Res. , vol.528 , pp. 162-164
    • Del Cerro, S.1    Borrell, J.2
  • 16
    • 0025777448 scopus 로고
    • Interleukin-1 and interleukin-1 antagonism
    • C.A. Dinarello Interleukin-1 and interleukin-1 antagonism Blood 77 1991 1627 1652
    • (1991) Blood , vol.77 , pp. 1627-1652
    • Dinarello, C.A.1
  • 17
    • 0026763167 scopus 로고
    • Endotoxin-induced activation of cerebral catecholamine and 5-HT metabolism: Comparison with interleukin-1
    • A.J. Dunn Endotoxin-induced activation of cerebral catecholamine and 5-HT metabolism: comparison with interleukin-1 J. Pharmacol. Exp. Ther. 261 1992 964 969
    • (1992) J. Pharmacol. Exp. Ther. , vol.261 , pp. 964-969
    • Dunn, A.J.1
  • 18
    • 0033675213 scopus 로고    scopus 로고
    • Cytokine activation of the HPA axis
    • A.J. Dunn Cytokine activation of the HPA axis Ann. NY Acad. Sci. 917 2000 608 617
    • (2000) Ann. NY Acad. Sci. , vol.917 , pp. 608-617
    • Dunn, A.J.1
  • 19
    • 0025851984 scopus 로고
    • Reduction of exploratory behavior by intraperitoneal injection of interleukin-1 involves brain corticotropin-releasing factor
    • A.J. Dunn, M. Antoon, and Y. Chapman Reduction of exploratory behavior by intraperitoneal injection of interleukin-1 involves brain corticotropin- releasing factor Brain Res. Bull. 26 1991 539 542
    • (1991) Brain Res. Bull. , vol.26 , pp. 539-542
    • Dunn, A.J.1    Antoon, M.2    Chapman, Y.3
  • 20
    • 0026091836 scopus 로고
    • Stress- and endotoxin-induced increases in brain tryptophan and 5-HT metabolism depend on sympathetic nervous system activity
    • A.J. Dunn, and J. Welch Stress- and endotoxin-induced increases in brain tryptophan and 5-HT metabolism depend on sympathetic nervous system activity J. Neurochem. 57 1991 1615 1622
    • (1991) J. Neurochem. , vol.57 , pp. 1615-1622
    • Dunn, A.J.1    Welch, J.2
  • 21
    • 0025021471 scopus 로고
    • Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist
    • S.P. Eisenberg, R.J. Evans, W.P. Arend, E. Verderber, M.T. Brewer, C.H. Hannum, and R.C. Thompson Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist Nature 343 1990 341 346
    • (1990) Nature , vol.343 , pp. 341-346
    • Eisenberg, S.P.1    Evans, R.J.2    Arend, W.P.3    Verderber, E.4    Brewer, M.T.5    Hannum, C.H.6    Thompson, R.C.7
  • 22
    • 0021867037 scopus 로고
    • Interleukin 1-like factors can accumulate 5-hydroxytryptamine in the liver of mice and can induce hypoglycaemia
    • Y. Endo, R. Suzuki, and K. Kumagai Interleukin 1-like factors can accumulate 5-hydroxytryptamine in the liver of mice and can induce hypoglycaemia Biochim. Biophys. Acta 840 1985 37 42
    • (1985) Biochim. Biophys. Acta , vol.840 , pp. 37-42
    • Endo, Y.1    Suzuki, R.2    Kumagai, K.3
  • 23
    • 0026041482 scopus 로고
    • Activation of the hypothalamic 5-HTergic system by central interleukin-1
    • C. Gemma, P. Ghezzi, and M.G. de Simoni Activation of the hypothalamic 5-HTergic system by central interleukin-1 Eur. J. Pharmacol. 209 1991 139 140
    • (1991) Eur. J. Pharmacol. , vol.209 , pp. 139-140
    • Gemma, C.1    Ghezzi, P.2    De Simoni, M.G.3
  • 24
    • 0029027101 scopus 로고
    • Spatial learning impairment in mice infected with Legionella pneumophila or administered exogenous interleukin-1-β
    • M. Gibertini, C. Newton, H. Friedman, and T.W. Klein Spatial learning impairment in mice infected with Legionella pneumophila or administered exogenous interleukin-1-β Brain Behav. Immun. 9 1995 113 128
    • (1995) Brain Behav. Immun. , vol.9 , pp. 113-128
    • Gibertini, M.1    Newton, C.2    Friedman, H.3    Klein, T.W.4
  • 25
    • 0141450546 scopus 로고    scopus 로고
    • The role of endogenous interleukin-1 in stress-induced adrenal activation and adrenalectomy-induced adrenocorticotropic hormone hypersecretion
    • I. Goshen, R. Yirmiya, K. Iverfeldt, and J. Weidenfeld The role of endogenous interleukin-1 in stress-induced adrenal activation and adrenalectomy-induced adrenocorticotropic hormone hypersecretion Endocrinology 144 2003 4453 4458
    • (2003) Endocrinology , vol.144 , pp. 4453-4458
    • Goshen, I.1    Yirmiya, R.2    Iverfeldt, K.3    Weidenfeld, J.4
  • 27
    • 0018759558 scopus 로고
    • Plasma corticosterone concentrations sensitively reflect levels of stimulus intensity in the rat
    • M.B. Hennessy, J.P. Heybach, J. Vernikos, and S. Levine Plasma corticosterone concentrations sensitively reflect levels of stimulus intensity in the rat Physiol. Behav. 22 1979 821 825
    • (1979) Physiol. Behav. , vol.22 , pp. 821-825
    • Hennessy, M.B.1    Heybach, J.P.2    Vernikos, J.3    Levine, S.4
  • 30
    • 0031595002 scopus 로고    scopus 로고
    • Influence of interleukin-1β on exploratory behaviors, plasma ACTH, corticosterone, and central biogenic amines in mice
    • S. Lacosta, Z. Merali, and H. Anisman Influence of interleukin-1β on exploratory behaviors, plasma ACTH, corticosterone, and central biogenic amines in mice Psychopharmacology 137 1998 351 361
    • (1998) Psychopharmacology , vol.137 , pp. 351-361
    • Lacosta, S.1    Merali, Z.2    Anisman, H.3
  • 31
    • 1642633568 scopus 로고    scopus 로고
    • Activation of the hypothalamic-pituitary-adrenal axis in IL-1β-converting enzyme-deficient mice
    • S. Liege, E. Moze, P. Parnet, K.W. Kelley, and P.J. Neveu Activation of the hypothalamic-pituitary-adrenal axis in IL-1β-converting enzyme-deficient mice Neuroimmunomodulation 7 2000 189 194
    • (2000) Neuroimmunomodulation , vol.7 , pp. 189-194
    • Liege, S.1    Moze, E.2    Parnet, P.3    Kelley, K.W.4    Neveu, P.J.5
  • 32
    • 0028092812 scopus 로고
    • Local administration of recombinant human interleukin-1beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary- adrenocortical axis activity, and body temperature
    • A.C. Linthorst, C. Flachskamm, F. Holsboer, and J.M. Reul Local administration of recombinant human interleukin-1beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature Endocrinology 135 1994 520 532
    • (1994) Endocrinology , vol.135 , pp. 520-532
    • Linthorst, A.C.1    Flachskamm, C.2    Holsboer, F.3    Reul, J.M.4
  • 33
    • 0028968980 scopus 로고
    • Effect of bacterial endotoxin and interleukin-1beta on hippocampal serotonergic neurotransmission, behavioural activity, and free corticosterone levels: An in vivo microdialysis study
    • A.C. Linthorst, C. Flachskamm, P. Muller-Preuss, F. Holsboer, and J.M. Reul Effect of bacterial endotoxin and interleukin-1beta on hippocampal serotonergic neurotransmission, behavioural activity, and free corticosterone levels: an in vivo microdialysis study J. Neurosci. 15 1995 2920 2934
    • (1995) J. Neurosci. , vol.15 , pp. 2920-2934
    • Linthorst, A.C.1    Flachskamm, C.2    Muller-Preuss, P.3    Holsboer, F.4    Reul, J.M.5
  • 34
    • 0037376813 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type I receptor
    • C.E. Loscher, K.H. Mills, and M.A. Lynch Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type I receptor J. Neuroimmunol. 137 2003 117 124
    • (2003) J. Neuroimmunol. , vol.137 , pp. 117-124
    • Loscher, C.E.1    Mills, K.H.2    Lynch, M.A.3
  • 36
    • 0029670054 scopus 로고    scopus 로고
    • Modulation of IL-1β gene expression in the rat CNS during sleep deprivation
    • M. Mackiewicz, P.J. Sollars, M.D. Ogilvie, and A.I. Pack Modulation of IL-1β gene expression in the rat CNS during sleep deprivation Neuroreport 7 1996 529 533
    • (1996) Neuroreport , vol.7 , pp. 529-533
    • MacKiewicz, M.1    Sollars, P.J.2    Ogilvie, M.D.3    Pack, A.I.4
  • 37
    • 0141784866 scopus 로고    scopus 로고
    • IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions
    • T. Matsuki, R. Horai, K. Sudo, and Y. Iwakura IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions J. Exp. Med. 198 2003 877 888
    • (2003) J. Exp. Med. , vol.198 , pp. 877-888
    • Matsuki, T.1    Horai, R.2    Sudo, K.3    Iwakura, Y.4
  • 38
    • 0022399614 scopus 로고
    • Suppression of food intake during infection: Is interleukin-1 involved?
    • D.O. McCarthy, M.J. Kluger, and A.J. Vander Suppression of food intake during infection: is interleukin-1 involved? Am. J. Clin. Nutr. 42 1985 1179 1182
    • (1985) Am. J. Clin. Nutr. , vol.42 , pp. 1179-1182
    • McCarthy, D.O.1    Kluger, M.J.2    Vander, A.J.3
  • 39
    • 0025305846 scopus 로고
    • Increased biogenic amine release in mouse hypothalamus following immunological challenge: Antagonism by indomethacin
    • I.N. Mefford, and M.P. Heyes Increased biogenic amine release in mouse hypothalamus following immunological challenge: antagonism by indomethacin J. Neuroimmunol. 27 1990 55 61
    • (1990) J. Neuroimmunol. , vol.27 , pp. 55-61
    • Mefford, I.N.1    Heyes, M.P.2
  • 40
    • 0027189927 scopus 로고
    • Systemic administration of interleukin-1 stimulates norepinephrine release in the paraventricular nucleus
    • P.S. Mohankumar, and S.K. Quadri Systemic administration of interleukin-1 stimulates norepinephrine release in the paraventricular nucleus Life Sci. 52 1993 1961 1967
    • (1993) Life Sci. , vol.52 , pp. 1961-1967
    • Mohankumar, P.S.1    Quadri, S.K.2
  • 41
    • 0025958744 scopus 로고
    • Interleukin-1 stimulates the release of DA and dihydroxyphenylacetic acid from the hypothalamus in vivo
    • P.S. Mohankumar, S. Thyagarajan, and S.K. Quadri Interleukin-1 stimulates the release of DA and dihydroxyphenylacetic acid from the hypothalamus in vivo Life Sci. 48 1991 925 930
    • (1991) Life Sci. , vol.48 , pp. 925-930
    • Mohankumar, P.S.1    Thyagarajan, S.2    Quadri, S.K.3
  • 42
    • 0027222987 scopus 로고
    • Interleukin-1β increases 5-hydroxyindoleacetic acid release in the hypothalamus in vivo
    • P.S. Mohankumar, S. Thyagarajan, and S.K. Quadri Interleukin-1β increases 5-hydroxyindoleacetic acid release in the hypothalamus in vivo Brain Res. Bull. 31 1993 745 748
    • (1993) Brain Res. Bull. , vol.31 , pp. 745-748
    • Mohankumar, P.S.1    Thyagarajan, S.2    Quadri, S.K.3
  • 43
    • 0032148393 scopus 로고    scopus 로고
    • Specificity of interleukin-1β-induced changes in monoamine concentrations in hypothalamic nuclei: Blockade by interleukin-1 receptor antagonist
    • S.M. Mohankumar, P.S. Mohankumar, and S.K. Quadri Specificity of interleukin-1β-induced changes in monoamine concentrations in hypothalamic nuclei: blockade by interleukin-1 receptor antagonist Brain Res. Bull. 47 1998 29 34
    • (1998) Brain Res. Bull. , vol.47 , pp. 29-34
    • Mohankumar, S.M.1    Mohankumar, P.S.2    Quadri, S.K.3
  • 44
    • 58149446368 scopus 로고
    • The relation between fear induced by novel stimulation and exploratory behaviour
    • K.C. Montgomery The relation between fear induced by novel stimulation and exploratory behaviour J. Comp. Physiol. Psychol. 48 1955 254 260
    • (1955) J. Comp. Physiol. Psychol. , vol.48 , pp. 254-260
    • Montgomery, K.C.1
  • 46
    • 0027310841 scopus 로고
    • Interleukin-1β, but not interleukin-6, impairs spatial navigation learning
    • M.S. Oitzl, H. van Oers, B. Schobitz, and E.R. de Kloet Interleukin-1β, but not interleukin-6, impairs spatial navigation learning Brain Res. 613 1993 160 163
    • (1993) Brain Res. , vol.613 , pp. 160-163
    • Oitzl, M.S.1    Van Oers, H.2    Schobitz, B.3    De Kloet, E.R.4
  • 48
    • 0031773020 scopus 로고    scopus 로고
    • Selective effects of peripheral lipopolysaccharide administration on contextual and auditory-cue fear conditioning
    • C.R. Pugh, K. Kumagawa, M. Fleshner, L.R. Watkins, S.F. Maier, and J.W. Rudy Selective effects of peripheral lipopolysaccharide administration on contextual and auditory-cue fear conditioning Brain Behav. Immun. 12 1998 212 229
    • (1998) Brain Behav. Immun. , vol.12 , pp. 212-229
    • Pugh, C.R.1    Kumagawa, K.2    Fleshner, M.3    Watkins, L.R.4    Maier, S.F.5    Rudy, J.W.6
  • 51
    • 0028921364 scopus 로고
    • Involvement of interleukin-1 in immobilization stress-induced increase in plasma adrenocorticotropic hormone and in release of hypothalamic monoamines in the rat
    • F. Shintani, T. Nakaki, S. Kanba, K. Sato, G. Yagi, M. Shiozawa, S. Aiso, R. Kato, and M. Asai Involvement of interleukin-1 in immobilization stress-induced increase in plasma adrenocorticotropic hormone and in release of hypothalamic monoamines in the rat J. Neurosci. 15 1995 1961 1970
    • (1995) J. Neurosci. , vol.15 , pp. 1961-1970
    • Shintani, F.1    Nakaki, T.2    Kanba, S.3    Sato, K.4    Yagi, G.5    Shiozawa, M.6    Aiso, S.7    Kato, R.8    Asai, M.9
  • 52
    • 0025610125 scopus 로고
    • Intracerebroventricular administration of interleukin-1 to mice alters investigation of stimuli in a novel environment
    • F. Spadaro, and A.J. Dunn Intracerebroventricular administration of interleukin-1 to mice alters investigation of stimuli in a novel environment Brain Behav. Immun. 4 1990 308 322
    • (1990) Brain Behav. Immun. , vol.4 , pp. 308-322
    • Spadaro, F.1    Dunn, A.J.2
  • 53
    • 0036675515 scopus 로고    scopus 로고
    • Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist
    • R. Tehranian, S. Andell-Jonsson, S.M. Beni, I. Yatsiv, E. Shohami, T. Bartfai, J. Lundkvist, and K. Iverfeldt Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist J. Neurotrauma 19 2002 939 951
    • (2002) J. Neurotrauma , vol.19 , pp. 939-951
    • Tehranian, R.1    Andell-Jonsson, S.2    Beni, S.M.3    Yatsiv, I.4    Shohami, E.5    Bartfai, T.6    Lundkvist, J.7    Iverfeldt, K.8
  • 54
    • 0032905515 scopus 로고    scopus 로고
    • Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: Actions and mechanisms of action
    • A.V. Turnbull, and C.L. Rivier Regulation of the hypothalamic-pituitary- adrenal axis by cytokines: actions and mechanisms of action Physiol. Rev. 79 1999 1 71
    • (1999) Physiol. Rev. , vol.79 , pp. 1-71
    • Turnbull, A.V.1    Rivier, C.L.2
  • 55
    • 0023205034 scopus 로고
    • Interleukin-1 stimulates ACTH release by an indirect action which requires endogenous corticotropin releasing factor
    • A. Uehara, P.E. Gottschall, R.R. Dahl, and A. Arimura Interleukin-1 stimulates ACTH release by an indirect action which requires endogenous corticotropin releasing factor Endocrinology 121 1987 1580 1582
    • (1987) Endocrinology , vol.121 , pp. 1580-1582
    • Uehara, A.1    Gottschall, P.E.2    Dahl, R.R.3    Arimura, A.4
  • 57
    • 0030024691 scopus 로고    scopus 로고
    • Possible involvement of glucocorticoids in the modulation of interleukin-1-induced cardiovascular responses in rats
    • T. Watanabe, N. Tan, Y. Saiki, T. Makisumi, and S. Nakamura Possible involvement of glucocorticoids in the modulation of interleukin-1-induced cardiovascular responses in rats J. Physiol. 491 1996 231 239
    • (1996) J. Physiol. , vol.491 , pp. 231-239
    • Watanabe, T.1    Tan, N.2    Saiki, Y.3    Makisumi, T.4    Nakamura, S.5
  • 58
    • 0036433397 scopus 로고    scopus 로고
    • Brain interleukin-1 is involved in spatial memory and passive avoidance conditioning
    • R. Yirmiya, G. Winocur, and I. Goshen Brain interleukin-1 is involved in spatial memory and passive avoidance conditioning Neurobiol. Learn. Mem. 78 2002 379 389
    • (2002) Neurobiol. Learn. Mem. , vol.78 , pp. 379-389
    • Yirmiya, R.1    Winocur, G.2    Goshen, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.