Measurement of nuchal skin fold thickness in the second trimester: Influence of imaging angle and fetal presentation

Ultrasound in Obstetrics and Gynecology

Volumn 25, Issue 3, 2005, Pages 253-257

  Cho, J Y ^a   Kim, K W ^a   Lee, Y H ^a   Toi, A ^b  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Down syndrome; Nuchal skin fold thickness; Ultrasound

Indexed keywords

ARTICLE; BREECH PRESENTATION; CHROMOSOME ABERRATION; FEMALE; FETUS; FETUS ECHOGRAPHY; GESTATIONAL AGE; HUMAN; OCCIPITAL BONE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SECOND TRIMESTER PREGNANCY; SKINFOLD THICKNESS;

BREECH PRESENTATION; CASE-CONTROL STUDIES; FEMALE; FETAL DISEASES; HUMANS; NUCHAL TRANSLUCENCY MEASUREMENT; POSTURE; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREGNANCY TRIMESTER, SECOND; PROSPECTIVE STUDIES; SKINFOLD THICKNESS;

EID: 15944365515     PISSN: 09607692     EISSN: None     Source Type: Journal    
DOI: 10.1002/uog.1847     Document Type: Article

References (23)

1. Benacerraf BR, Barss VA, Laboda LA. A sonographic sign for the detection in the second trimester of the fetus with Down's syndrome. Am J Obstet Gynecol 1985; 151: 1078-1079.
2. Benacerraf BR, Frigoletto FD, Laboda LA. Sonographic diagnosis of Down syndrome in the second trimester. Am J Obstet Gynecol 1985; 153: 49-52.
3. Benacerraf BR, Frigoletto FD, Cramer DW. Down syndrome: sonographic sign for diagnosis in the second-trimester fetus. Radiology 1987; 163: 811-813.
4. Benacerraf BR, Gelman R, Frigoletto FD. Sonographic identification of second trimester fetuses with Down's syndrome. N Engl J Med 1987; 317: 1371-1376.
5. Bromley B, Benacerraf BR. The resolving nuchal fold in second trimester fetuses: not necessarily reassuring. J Ultrasound Med 1995; 14: 253-255.
6. Lynch L, Berkowitz GS, Chitkara U, Wilkins IA, Mehalek KE, Berkowitz RL. Ultrasound detection of Down syndrome: is it really possible? Obstet Gynecol 1989; 73: 267-270.
7. Crane JP, Gray DL. Sonographically measured nuchal skin fold thickness as a screening tool for Down syndrome: results of a prospective clinical trial. Obstet Gynecol 1991; 77: 533-536.
8. Watson WJ, Miller RC, Menard MK. Ultrasonographic measurement of fetal nuchal skin to screen for chromosomal abnormalities. Am J Obstet Gynecol 1994; 170: 583-586.
9. Grandjean H, Sarramon M-F. Femur/foot length ratio for detection of Down syndrome: results of a multicenter prospective study. Am J Obstet Gynecol 1995; 173: 16-19.
10. Borrell A, Costa D, Martinez JM, Delgado RD, Casals E, Ojuel J, Fortuny A. Early midtrimester fetal nuchal thickness: effectiveness as a marker of Down syndrome. Am J Obstet Gynecol 1996; 175: 45-49.
11. Ginsberg N, Cadkin A, Pergament E, Verlinsky Y. Ultrasonographic detection of the second-trimester fetus with trisomy 18 and trisomy 21. Am J Obstet Gynecol 1990; 163: 1186-1190.
12. Nyberg DA, Resta RG, Luthy DA, Hickok DE, Mahony BS, Hirsch JH. Prenatal sonographic findings of Down syndrome: review of 94 cases. Obstet Gynecol 1990; 76: 370-377.
13. Perrella R, Duerinck AJ, Grant EG, Tessler F, Tabsh K, Crandall BF. Second-trimester sonographic diagnosis of Down syndrome: role of femur-length shortening and nuchal-fold thickening. AJR Am J Roentgenol 1988; 151: 981-985.
14. Hill LM, Guzick D, Belfar HL, Hixson J, Rivello D, Rusnak J. The current role of sonography in the detection of Down syndrome. Obstet Gynecol 1989; 74: 620-623.
15. Benacerraf BR, Cnann A, Gelman R, Laboda LA, Frigoletto FD. Can sonographers reliably identify anatomic features associated with Down syndrome in fetuses? Radiology 1989; 173: 377-380.
16. Lockwood CJ, Lynch L, Ghidini A. The effect of fetal gender on the prediction of Down syndrome by means of maternal serum α-fetoprotein and ultrasonographic parameters. Am J Obstet Gynecol 1993; 169: 1190-1197.
17. Benacerraf BR, Neuberg D, Frigoletto FD. Humeral shortening in second-trimester fetuses with Down syndrome. Obstet Gynecol 1991; 77: 223-227.
18. Benacerraf BR, Frigoletto FD. Soft tissue nuchal fold in the second-trimester fetus: standards for normal measurements compared with those in Down syndrome. Am J Obstet Gynecol 1987; 157: 1146-1149.
19. Toi A, Simpson GF, Filly RA. Ultrasonically evident fetal nuchal skin thickening: is it specific for Down syndrome? Am J Obstet Gynecol 1987; 156: 150-153.
20. Kirk JS, Comstock CH, Fassnacht MA, Yang SS, Lee W. Routine measurement of nuchal thickness in the second trimester. J Matern Fetal Med 1992; 1: 82-86.
21. DeVore GR, Alfi O. The association between an abnormal nuchal skin fold, trisomy 21, and ultrasound abnormalities identified during the second trimester of pregnancy. Ultrasound Obstet Gynecol 1993; 3: 387-394.
22. Crane JP, Gray DL. Optimal nuchal skin-fold thresholds based on gestational age for prenatal detection of Down syndrome. Am J Obstet Gynecol 1994; 171: 1282-1286.
23. Lee PR, Won HS, Chung JY, Shin HJ, Kim A. The variables affecting nuchal skin-fold thickness in mid-trimester. Prenat Diagn 2003; 23: 60-64.