Electrochemical characterization of flupenthixol and rapid determination of the drug in human serum and pharmaceuticals by voltammetry

Analytical Letters

Volumn 38, Issue 4, 2005, Pages 641-656

  Dogan, Burcu ^a   Özkan, Sibel A ^a   Uslu, Bengi ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Biological samples; Flupenthixol hydrochloride; Pharmaceuticals; Voltammetry

Indexed keywords

CARBON; CHLORPROMAZINE; FLUPENTIXOL; FLUPHENAZINE; PHENOTHIAZINE; THIOXANTHENE DERIVATIVE;

ACCURACY; ARTICLE; DEPRESSION; DIFFERENTIAL PULSE VOLTAMMETRY; DIFFUSION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSAGE FORM; DRUG OXIDATION; DRUG STRUCTURE; ELECTROCHEMICAL ANALYSIS; NONHUMAN; PH; POTENTIOMETRY; SQUARE WAVE VOLTAMMETRY;

EID: 15944365210     PISSN: 00032719     EISSN: None     Source Type: Journal    
DOI: 10.1081/AL-200050312     Document Type: Article

References (31)

1. Alvarez-Lueje, A., Sturm, J.C., Nunez-Vergara, L.J., Carbajo, J., and Squella, J. 2000. Voltammetric behaviour of clonixin and its differential pulse polarographic determination in tablets. Anal. Lett., 33: 53-68.
2. Aly, F.A., Al-Tamimi, S.A., and Alwarthan, A.A. 2001. Flow-injection chemilumino-metric determination of some thioxanthene derivatives in pharmaceutical formulations and biological fluids the [Ru(dipy)3(2+)]-Ce(IV) system. Anal. Sci., 17: 1257-1261.
3. Balant-Gargia, A.E., Balant, L.P., Genet, C., and Eisele, R. 1985. Comparative determination of flupentixol in plasma by gas chromatography and radio immunoassay in schizophrenic patients. Ther. Drug Monit., 7: 229-235.
4. Belal, F., İbrahim, F., Hassan, S.M., and Aly, F.A. 1991. Spectroflourimetric determination of some pharmaceutically important thioxanthene derivatives. Anal. Chim. Acta, 255: 103-106.
5. Belal, F., Al-Majed, A., Ibrahim, K.E.E., and Khalil, N.Y. 2002. Voltammetric determination of josamycin (amacrolide antibiotic) in dosage forms and spiked human urine. J. Pharm. Biomed. Anal., 30: 705-713.
6. Berzas-Nevado, J.J., Rodroguez Flores, J., and Castaneda Penalvo, G. 2000. Voltammetric behaviour of fluvoxamine using square-wave and adsorptive stripping square-wave techniques. Determination in pharmaceutical products. Electroanalysis, 12: 1059-1063.
7. Franke, U.J. 2000. PhD thesis: Quantitative Analyse von Arzneistaff- Membran-Wechsel-Wirkungen am Beispiel von Neuroleptika und Calcium-Kanal- Blockern, Martin Luther Universität Halle: Wittenberg, Electronic document.
8. Garcia, L.G., Forfar-Bares, I., Pehourcq, F., and Jarry, C. 2003. Simultaneous determination of four antipsychotic drugs in plasma by high-performance liquid chromatography-Application to management of acute intoxications. J. Chromatogr. B, 795: 257-264.
9. Greef, R., Peat, R., Peter, L.M., Pletcher, D., and Robinson, J. 1985. Instrumental Methods in Electrochemistry; Chichester: Ellis Horwood, pp. 185-189.
10. Grimshaw, J. 2000. Electrochemical Reactions and Mechanisms in Organic Chemistry; New York: Elsevier, p. 229.
11. Hassan, S.M., Belal, F., İbrahim, F., and Aly, F.A. 1989. Fluorometric determination of some thioxanthene derivatives in dosage forms. Talanta, 36: 557-560.
12. Kauffmann, J.-M. and Vire, J.-C. 1993. Pharmaceutical and biomedical applications of electroanalysis: a critical review. Anal. Chim. Acta, 273: 329-334.
13. Kauffmann, J.M., Vire, J.C., Patriarche, G.J., Nunez-Vergara, L.J., and Squella, J.A. 1987. Voltammetric oxidation of trazodone. Electrochim. Acta, 32: 1159-1162.
14. Kissinger, P.T. and Heineman, W.R. 1996. Laboratory Techniques in Electroanalytical Chemistry, 2nd ed.; New York: Marcel Dekker.
15. Kratzsch, C., Peters, F.T., Kraemer, T., Weber, A.A., and Maurer, H.H. 2003. Screening, library-assisted identification and validated quantification of fifteen neuroleptics and three of their metabolites in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionisation. J. Mass Spectrom., 38: 283-295.
16. Laviron, E., Roullier, L., and Degrand, C. 1980. A multiplayer model for the study of space distributed redox modified electrodes: Part II. Theory and application of linear potential sweep voltammetry for a simple reaction. J. Electroanal. Chem., 112: 11-23.
17. McClean, S., O'Kane, E.J., and Smyth, W.F. 2000. Electrospray ionisation-mass spectrometric characterisation of selected anti-psychotic drugs and their detection and determination in human hair samples by liquid chromatography-tandem mass spectrometry. J. Chromatogr. B, 740: 141-157.
18. Özkan, S.A., Uslu, B., and Aboul-Enein, H.Y. 2003. Voltammetric investigation of tamsulosin. Talanta, 61: 147-156.
19. Özkan, S.A., Uslu, B., and Şentürk, Z. 2004. Electroanalytical characteristics of amisulpride and voltammetric determination of the drug in pharmaceuticals and biological media. Electroanalysis, 16: 231-237.
20. Özkan, S.A., Uslu, B., and Zuman, P. 2004. Electrochemical oxidation of sildenafil citrate (Viagra) on carbon electrodes. Anal. Chim. Acta, 501: 227-233.
21. Riley, C.M. and Rosanske, T.W. 1996. Development and Validation of Analytical Methods; New York: Elsevier Science Ltd.
22. Şentürk, Z., Özkan, S.A., Uslu, B., and Biryol, İ. 1996. Anodic voltammetry of fluphenazine at different solid electrodes. J. Pharm. Biomed. Anal., 15: 365-370.
23. Şentürk, Z., Özkan, S.A., Özkan, Y., and Aboul-Enein, H.Y. 2000. Voltammetric investigation of oxidation of zuclopenthixol and application to its determination in dosage forms and in drug dissolution studies. J. Pharm. Biomed. Anal., 22: 315-323.
24. Shehata, I.A., El-Ashry, S.M., EL-Sherbeny, M.A., El-Sherbeny, D.T., and Belal, F.J. 2000. Fluorimetric determination of some thioxanthene derivatives in dosage forms and biological fluids. Pharm. Biomed. Anal., 22: 729-737.
25. Swartz, M.E. and Krull, I.S. 1997. Analytical Method Development and Validation; New York: Marcel Dekker.
26. Sweetman, S.C. 2002. Martindale, The Complete Drug Reference, 33th ed.; Sweetman, S.C., ed., 684: London: Pharmaceutical Press.
27. Uslu, B. and Özkan, S.A. 2004. Anodic voltammetry of abacavir and its determination in pharmaceuticals and biological fluids. Electrochim. Acta, 49: 4321-4329.
28. Uslu, B. and Özkan, S.A. 2002. Electrochemical characterisation of nefazodone hydrochloride and voltammetric determination of the drug in pharmaceuticals and human serum. Anal. Chim. Acta, 462: 49-57.
29. Yilmaz, S., Uslu, B., and Özkan, S.A. 2001. Anodic oxidation of etodolac and its square wave and differential pulse voltammetric determination in pharmaceuticals and human serum. Talanta, 54: 351-360.
30. Wang, J. 1988. Electroanalytical Techniques in Clinical Chemistry and Laboratory Medicine; New York: VCH.
31. Wang, J. 2000. Analytical Electrochemistry, 2nd ed.; New York: Wiley-VCH.