The influence of growth hormone (GH) therapy on cardiac performance in patients with childhood onset GH deficiency

Growth Hormone and IGF Research

Volumn 15, Issue 2, 2005, Pages 156-164

  Minczykowski, A ^a   Gryczynska, M ^a   Ziemnicka, K ^a   Czepczynski, R ^a   Sowinski, J ^a   Wysocki, H ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Echocardiography; Exercise test; Growth hormone deficiency; MPI; SPECT

Indexed keywords

HUMAN GROWTH HORMONE; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; SOMATOMEDIN C;

ADULT; ARTICLE; CHILDHOOD DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLE; DIASTOLIC BLOOD PRESSURE; DOPPLER ECHOCARDIOGRAPHY; EVIDENCE BASED MEDICINE; EXERCISE ELECTROCARDIOGRAPHY; EXERCISE TOLERANCE; FEMALE; GROWTH HORMONE DEFICIENCY; HEART DEVELOPMENT; HEART EJECTION FRACTION; HEART FUNCTION; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE SIZE; HEART MUSCLE PERFUSION; HEART PERFORMANCE; HEART RATE; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE SEPTUM; HORMONE SUBSTITUTION; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STATISTICAL SIGNIFICANCE; SYSTOLE; SYSTOLIC BLOOD PRESSURE; TREADMILL EXERCISE;

ADOLESCENT; ADULT; BLOOD PRESSURE; ECHOCARDIOGRAPHY, DOPPLER; ELECTROCARDIOGRAPHY; EXERCISE TEST; FEMALE; HEART; HEART RATE; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MIDDLE AGED; RADIONUCLIDE ANGIOGRAPHY; STROKE VOLUME; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; VENTRICULAR FUNCTION, LEFT;

EID: 15944364474     PISSN: 10966374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ghir.2005.01.001     Document Type: Article

References (49)

1. T. Rosén B.A. Bengtsson Premature mortality due to cardio-vascular disease in hypopituitarism Lancet 336 1990 285-288
2. B. Bulow L. Hagmar Z. Mikoczy C.H. Nordstrom E.M. Erfurth Increased cerebrovascular mortality in patients with hypopituitarism Clin. Endocrinol. 46 1997 75-81
3. J. Isgaard A.E. Tivesten P. Friberg B.-A.E. Bengtsson The role of the GH/ IGF-I axis for cardiac function and structure Horm. Metab. Res. 31 1999 50-54
4. A.H. Guse W. Kiess B. Funk U. Kessler I. Berg G. Gercken Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: Linkage to inositol 1,4,5-triphosphateformation formation Endocrinology 130 1992 145-151
5. M.Y. Donath J. Zapf M. Eppenberger-Eberhardt E.R. Froesch H.M. Eppenberger Insulin-like growth factor I stimulates myofibril development and decreases smooth muscle I-actin of adult cardiomyocytes Proc. Natl. Acad. Sci. USA 91 1994 1686-1690
6. N.S. Freestone S. Ribaric W.T. Mason The effect of insulin-like growth factor-I on adult rat cardiac contractility Mol. Cell. Biochem. 163/164 1996 223-229
7. A.F. Attanasio S.W.J. Lamberts A.M.C. Matranga et al. Adult growth hormone (GH)-deficient patients demonstrate heterogeneity between childhood onset and adult onset before and during human GH treatment J. Clin. Endocrinol. Metab. 82 1997 82-88
8. S. Fazio A. Cittadini D. Sabatini et al. Growth hormone and heart performance. A novel mechanism of cardiac wall stress regulation in humans Eur. Heart J. 18 1997 340-347
9. A. Sartorio S. Ferrero A. Conti et al. Adults with childhood-onset growth hormone deficiency: Effects of growth hormone treatment on cardiac structure J. Intern. Med. 241 1997 515-520
10. A. Colao A. Cuocola C. Di Somma et al. Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study Clin. Endocrinol. (Oxf) 52 2000 447-455
11. M. Shahi S.A. Beshyah D. Hackett P.S. Sharp D.G. Johnston R.A. Foale Myocardial dysfunction in treated adult hypopituitarism: A possible explanation for increased cardiovascular mortality Br. Heart J. 67 1992 92-96
12. L. Thuesen J.O. Jorgensen J.R. Muller et al. Short and long-term cardiovascular effects of growth hormone therapy in growth hormone deficient adults Clin. Endocrinol. (Oxf) 41 1994 615-620
13. G. Johannsson B.A. Bengtsson B. Andersson J. Isgaard K. Caidahl Long-term cardiovascular effects of growth hormone treatment in GH-deficient adults. Preliminary data in a small group of patients Clin. Endocrinol. 45 1996 305-314
14. R.C. Cuneo F. Salomon P. Wilmshurst et al. Cardiovascular effects of growth hormone treatment in growth hormone deficient adults: Stimulation of the renin-aldosterone system Clin. Sci. (Lond) 81 1991 587-592
15. R. Nass R.M. Huber V. Klauss O.A. Muller J. Schopohl C.J. Strasburger Effect of growth hormone (hGH) replacement therapy on physical work capacity and cardiac and pulmonary function in patients with hGH deficiency acquired in adulthood J. Clin. Endocrinol. Metab. 80 1995 552-557
16. D.J. Sahn A. De Maria J. Kisslo A. Wejman The committee on M-mode standardization of the American Society of Echocardiography. Recommendations regarding quantification in M-mode echocardiography: results of a survey of echocardiographic measurements Circulation 58 1978 1072-1083
17. N.B. Schiller P.M. Shah M. Crawford et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation two-dimensional echocardiograms J. Am. Soc. Echocardiogr. 2 1989 358-367
18. G. de Simone R.B. Devereux M.J. Roman et al. Assessment of left ventricular function by the midwall fractional shortening/end-systolic stress relation in human hypertension J. Am. Coll. Cardiol. 23 1994 1444-1451 [erratum in J. Am. Coll. Cardiol. 24 (1994) 844]
19. D.B. Sadler G.P. Aurigemma D.W. Williams D.J. Reda B.J. Materson S. Gottdiener Systolic function in hypertensive men with concentric remodeling Hypertension 30 1997 777-781
20. W.H. Gaasch M.R. Zile P.K. Hashino et al. Stress-shortening relations and myocardial blood flow in compensated and failing canine hearts with pressure-overload hypertrophy Circulation 79 1989 872-883
21. J.N. Bella V. Palmieri J.E. Liu et al. Relationship between left ventricular diastolic relaxation and systolic function in hypertension. The Hypertension Genetic Epidemiology Network (HyperGEN) Study Hypertension 38 2001 424-428
22. N. Reichek J. Wilson M. St John Sutton T.A. Plappert S. Goldberg J.W. Hirshfeld Noninvasive determination of left ventricular end-systolic stress: Validation of the method and initial application Circulation 65 1982 99-109
23. R.B. Devereux D.R. Alonso E.M. Lutas et al. Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings Am. J. Cardiol. 57 1986 450-458
24. D. Levy R.J. Garrison D.D. Savage W.B. Kannel W.P. Castelli Prognostic implications of echocardiographically determined left ventricular mass in the Framingham heart study N. Engl. J. Med. 322 1990 1561-1566
25. K. Wachtell V. Palmieri M.H. Olsen et al. Urine albumin/creatinine ratio and echocardiographic left ventricular structure and function in hypertensive patients with electrocardiographic left ventricular hypertrophy: The LIFE study. Losartan intervention for endpoint reduction Am. Heart J. 143 2002 319-326
26. M.J. Roman T.G. Pickering J.E. Schwartz R. Pini R.B. Devereux Relation of arterial structure and function to left ventricular geometric patterns in hypertensive adults J. Am. Coll. Cardiol. 28 1996 751-756
27. A. Ganau R.B. Devereux M.J. Roman et al. Patterns of left ventricular hypertrophy and geometric remodelling in essential hypertension J. Am. Coll. Cardiol. 19 1992 1550-1558
28. C. Tei L.H. Ling D.O. Hodge et al. New index of combined systolic and diastolic myocardial performance: A simple and reproducible measure of cardiac function - study in normals and dilated cardiomyopathy J. Cardiol. 26 1995 357-366
29. G. Eto M. Ishi C. Tei et al. Assessment of global left ventricular function in normal children and in children with dilated cardiomiopathy J. Am. Soc. Echocardiogr. 12 1999 1058-1064
30. D. Morvan M. Komajda A. Grimaldi G. Turpin Y. Grosgogeat Cardiac hypertrophy and function in asymptomatic acromegaly Eur. Heart J. 12 1991 666-672
31. B. Merola A. Cittadini A. Colao et al. Cardiac structural and functional abnormalities in adult patients with growth hormone deficiency J. Clin. Endocrinol. Metab. 77 1993 1658-1661
32. A.G. Amato C. Carella S. Fazio et al. Body composition, bone metabolism, and heart structure and function in growth hormone (GH)-deficient adults before and after GH replacement therapy at low doses J. Clin. Endocrinol. Metabol. 77 1993 1671-1676
33. R. Valcavi O. Gaddi M. Zini et al. Cardiac performance and mass in adults with hypopituitariam: Effect of one year of growth hormone treatment J. Clin. Endocrinol. Metab. 80 1995 659-666
34. G. Shimuzu M.R. Zile A.S. Blaustein W.H. Gaasch Left ventricular chamber filling and midwall fiber lengthening in patients with left ventricular hypertrophy: Overestimation of fiber velocities by conventional midwall measurements Circulation 71 1985 266-272
35. G. Shimuzu Y. Hirota Y. Kita K. Kawamura T. Saito W.H. Gaasch Left ventricular midwall mechanics in systemic arterial hypertension: myocardial function is depressed in pressure-overload hypertrophy Circulation 83 1991 1676-1684
36. G. de Simone R.B. Devereux M.J. Koren P.N. Casale G.A. Mensah J.H. Laragh Midwall left ventricular mechanics: An independent predictor of cardiovascular risk in arterial hypertension Circulation 93 1996 259-265
37. G. de Simone R. Greco G.F. Mureddu et al. Relation of left ventricular diastolic properties to systolic function in arterial hypertension Circulation 101 2000 152-157
38. S.H. Poulsen J.C. Nielsen H.R. Andersen The influence of heart rate on the Doppler derived myocardial performance index J. Am. Soc. Echocardiogr. 13 2000 379-384
39. C. Tei R.A. Nishimura J.B. Seward A.J. Tajik Noninvasive Doppler-derived myocardial performance index: Correlation with simultaneous measurements of cardiac catheterization measurements J. Am. Soc. Echocardiogr. 10 1997 169-178
40. J.E. Møller S.H. Poulsen K. Egstrup Effect of preload alternations on a new Doppler echocardiographic index of combined systolic and diastolic performance J. Am. Soc. Echocardiogr. 12 1999 1065-1072
41. C. Tei K.S. Dujardin D.O. Hodge R.A. Kyle A.J. Tajik J.B. Seward Doppler index combining systolic and diastolic myocardial performance: Clinical value in cardiac amyloidosis J. Am. Coll. Cardiol. 28 1996 658-664
42. K.S. Dujardin C. Tei T.C. Yeo D.O. Hodge A. Rossi J.B. Seward Prognostic value of a Doppler index combining systolic and diastolic performance in idiopathic-dilated cardiomyopathy Am. J. Cardiol. 82 1998 1071-1076
43. A.S. Bates W. Van't Hoff P.J. Jones R.N. Clayton The effect of hypopituitarism on life expectancy J. Clin. Endocrinol. Metab. 81 1996 1169-1172
44. E.M. Erfurth B. Buelow Z. Mikozy C.H. Nordstroem L. Hagmar Increased cardiovascular mortality in patients with hypopituitarism Endocrinol. Metab. 3 Suppl. A 1996 121
45. V. Markussis S.A. Beshyah C. Fisher P. Sharp A.N. Nicolaides D.G. Johnston Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adults Lancet 340 1992 1188-1192
46. E.D. Lehmann K.D. Hopkins A.J. Weissberger R.G. Gosling P.H. Sonksen Aortic distensibility in growth hormone deficient adults Lancet 341 1993 309
47. J.O.L. Jorgensen S.A. Pedersen L. Thuesen et al. Beneficial effects of growth hormone treatment in GH-deficient adults Lancet 1 1989 1221-1225
48. H.M. Whitehead C. Boreham E.M. McIlrath et al. Growth hormone treatment of adults with growth hormone deficiency: Results of a 13-month placebo controlled cross-over study Clin. Endocrinol. (Oxf). 36 1992 45-52
49. R.C. Cuneo F. Salomon C.M. Wiles et al. Growth hormone treatment in growth hormone-deficient adults. II. Effects on exercise performance J. Appl. Physiol. 70 1991 695-700