Gambian trypanosomiasis and synergism between melarsoprol and eflornithine: First case report

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 90, Issue 3, 1996, Pages 315-

  Simarro, Pere P ^a,c   Asumu, Pedro Ndong ^b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b Natl Trypanosomiasis Contr Prog   (Equatorial Guinea)

^c CIDOB   (Spain)

Author keywords

Case report; Chemotherapy; Eflornithine; Equatorial Guinea; Melarsoprol; Synergism; Trypanosoma brucei gambiense; Trypanosomiasis

Indexed keywords

EFLORNITHINE; MELARSOPROL;

ADULT; ARTICLE; CASE REPORT; DRUG EFFICACY; DRUG POTENTIATION; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTE COUNT; LUMBAR PUNCTURE; MALE; ORAL DRUG ADMINISTRATION; TRYPANOSOMA; TRYPANOSOMIASIS;

TRYPANOSOMA; TRYPANOSOMA BRUCEI GAMBIENSE;

EID: 15844430230     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(96)90268-0     Document Type: Article

References (5)

1. Fairlamb, A. H. (1990). Novel approaches to the chemotherapy of trypanosomiasis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 84, 613-617.
2. Fairlamb, A. H., Henderson, G. B. & Cerami, A. (1989). Trypanothione is the primary target for arsenical drugs against African trypanosomiasis. Proceedings of the National Academy of Sciences of the USA, 86, 2607-2611.
3. Jennings, F. W. (1988). Chemotherapy of trypanosomiasis: the potentiation of melarsoprol by concurrent difluoromethylornithine (DFMO) treatment. Transactions of the Royal Society of Tropical Medicine and Hygiene, 82, 572-573.
4. Jennings, F. W. (1990). Combination chemotherapy and African trypanosomiasis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 84, 618-621.
5. WHO (1986). Epidemiology and Control of African Trypanosomiasis. Geneva: World Health Organization, Technical Report Series, no. 739.