4-[4-[(2-hydroxybenzoyl)amino]phenyl]butyric acid as a novel oral delivery agent for recombinant human growth hormone

Journal of Medicinal Chemistry

Volumn 39, Issue 13, 1996, Pages 2571-2578

  Leone Bay, Andrea ^a   Ho, Koc Kan ^a   Agarwal, Rajesh ^a   Baughman, Robert A ^a   Chaudhary, Kiran ^a   DeMorin, Frenel ^a   Genoble, Lise ^a   McInnes, Campbell ^a   Lercara, Christine ^a   Milstein, Sam ^a   O'Toole, Doris ^a   Sarubbi, Donald ^a   Variano, Bruce ^a   Paton, Duncan R ^a  

^a Emisphere Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 [(2 HYDROXYBENZOYL)AMINO]PHENYL]BUTYRIC ACID; BUTYRIC ACID DERIVATIVE; HUMAN GROWTH HORMONE; RECOMBINANT GROWTH HORMONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG ABSORPTION; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STRUCTURE; INTESTINE ABSORPTION; MALE; MONKEY; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANIMALS; DRUG CARRIERS; DRUG DESIGN; GROWTH HORMONE; HAPLORHINI; HUMANS; HYDROGEN BONDING; INTESTINAL ABSORPTION; MACACA FASCICULARIS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MOLECULAR STRUCTURE; PHENYLBUTYRATES; RATS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 15844414676     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960038f     Document Type: Article

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