Structure of the Ras-binding domain of c-Raf-1 as determined by NMR spectroscopy and identification of the region that interacts with Ras

Drug Design and Discovery

Volumn 13, Issue 3-4, 1996, Pages 83-93

  Donald Emerson, S ^a   Madison, Vincent S ^a   Palermo, Robert E ^a   Waugh, David S ^a   Scheffler, Julie E ^a   Tsao, Kwei Lan ^a   Kiefer, Susan E ^a   Liu, Shuang P ^a   Fry, David C ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

NMR; Protein structure; Raf; Ras; Signal transduction

Indexed keywords

PROTEIN SERINE THREONINE KINASE;

BINDING SITE; CONFERENCE PAPER; ENZYME BINDING; ENZYME STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONCOGENE RAS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

BINDING SITES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RAF; RAS PROTEINS; UBIQUITINS;

EID: 15844407657     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

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