Designing inhibitors of the metalloproteinase superfamily: Comparative analysis of representative structures

Drug Design and Discovery

Volumn 13, Issue 3-4, 1996, Pages 3-14

  Dhanaraj, Venugopal ^a   Ye, Qi Zhuang ^b   Johnson, Linda L ^b   Hupe, Donald J ^b   Ortwine, Daniel F ^b   Dunbar Jr , James B ^b   Rubin, J R ^b   Pavlovsky, A ^b   Humblet, Christine ^b   Blundell, Tom L ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b PFIZER INC   (United States)

Author keywords

Matrix metalloproteinases; Metzincins; Stromelysin; Structural comparisons; Zinc metalloproteinase superfamily

Indexed keywords

COLLAGENASE; METAL ION; METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR; STROMELYSIN; THERMOLYSIN;

CONFERENCE PAPER; DRUG BINDING SITE; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; PROTEIN DOMAIN; PROTEIN TERTIARY STRUCTURE;

BINDING SITES; CATALYSIS; COLLAGENASES; DRUG DESIGN; MATRIX METALLOPROTEINASE 3; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; THERMOLYSIN; ZINC;

EID: 15844394264     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

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