The roles of hedgehog, wingless and lines in patterning the dorsal epidermis in Drosophila

Development

Volumn 122, Issue 4, 1996, Pages 1083-1092

  Peter, Bokor ^a   DiNardo, Stephen ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Drosophila; Hedgehog; Lines; Segment polarity; Wingless

Indexed keywords

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; EMBRYO PATTERN FORMATION; EPIDERMIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; DROSOPHILA; DROSOPHILA PROTEINS; EPIDERMIS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; INSECT HORMONES; MEMBRANE PROTEINS; MORPHOGENESIS; MUTATION; PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTORS, CELL SURFACE; RNA, MESSENGER; SIGNAL TRANSDUCTION;

ANIMALIA; ERINACEIDAE;

EID: 15844390388     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (77)

1. Arora, K., Levine, M. S., and O'Connor, M. B. (1994). The screw gene encodes a ubiquitously expressed member of the TGF-beta family required for specification of dorsal cell fates in the Drosophila embryo. Genes Dev. 8, 2588-2601.
2. Baker, N. E. (1987). Molecular cloning of sequences from wingless a segment polarity gene in Drosophila: the spatial distribution of a transcript in embryos. EMBO J. 6, 1765-1773.
3. Baker, N. E. (1988). Embryonic and imaginai requirements for wg, a segment polarity gene in Drosophila. Dev. Biol. 125, 96-108.
4. Basler, K. and Struhl, G. (1994). Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 368, 208-214.
5. Bejsovec, A. and Martinez Arias, A. (1991). Roles of wingless in patterning the larval epidermis of Drosophila. Development 113, 471-485.
6. Bejsovec, A. and Wieschaus, E. (1993) Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. Development 119, 501-517.
7. Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
8. Cabrera, C. V., Alonso, M. C., Johnston, P., Phillips, R. G. and Lawrence, P. A. (1987). Phenocopies induced with antinsense RNA identify the wingless gene. Cell 50, 659-663.
9. Campbell, G., Weaver, T. and Tomlinson, A. (1993) Axis specification in the developing Drosophila appendage: the role of wingless, decapentaplegic, and the homeobox gene aristaless. Cell 74, 1113-23.
10. Campos-Ortega, J. A. and Hartenstein, V. (1985). "The embryonic development of Drosophila melanogaster." Springer-Verlag, New York.
11. Capdevila, J., Estrada, M. P., Sanchez, H. E. and Guerrero, I. (1994). The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development. Embo Journal 13, 71-82.
12. Capdevila, J. and Guerrero, I. (1994). Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings. EMBO J. 13, 4459-4468.
13. Chakrabarti, A., Matthews, G., Colman, A. and Dale, L. (1992). Secretory and inductive properties of Drosophila wingless protein in Xenopus oocytes and embryos. Development 115, 355-369.
14. Couso, J.P., Bate, M. and Martinez Arias, A. (1993). A wingless-dependent polar coordinate system in Drosophila imaginai discs. Science 259, 484 - 489.
15. Couso, J. P., Bishop, S. A. and Martinez Arias, A. (1994). The wingless signalling pathway and the patterning of the wing margin in Drosophila Development 120, 621-636.
16. Cumberledge, S. and Krasnow, M. A. (1993). Intercellular signalling in Drosophila segment formation reconstructed in vitro. Nature 363, 549-552.
17. Diaz-Benjumea, F. J., Cohen, B. and Cohen, S. M. (1994). Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs. Nature 372, 175-179
18. DiNardo, S., Sher, E., Heemskerk-Jongens, J., Kassis, J. A. and O'Farrell, P. H. (1988) Two-tiered regulation of spatially patterned engrailed gene expression during drosophila embryogenesis. Nature 332, 604-609.
19. Dougan, S. T. and DiNardo, S. (1992). wingless generates cell type diversity among engrailed expressing cells. Nature 360, 347 - 350.
20. Echelard, Y., Epstein, D. P., St-Jacques, B., Shen, L., Mohler, J., McMahon, J. A. and McMahon, A. P. (1993). Sonic hedgehog, a member of a family of putative signaling molecules is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.
21. Fan, C. M., Porter, J. A., Chiang, C., Chang, D. T., Beachy, P. A. and Tessier, L. M. (1995). Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway. Cell 81, 457-465.
22. Fan, C. M. and Tessier-Lavigne, M. (1994). Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog. Cell 79, 1175-1186.
23. Felsenfeld, A. L. and Kennison, J. A. (1995). Positional signaling by hedgehog in Drosophila imaginai disc development. Development 121, 1-10.
24. Fietz, M. J., Jacinto, A., Taylor, A. M., Alexandre, C. and Ingham, P. W. (1995). Secretion of the amino-terminal fragment of the Hedgehog protein is necessary and sufficient for hedgehog sianalina in Drosophila. Curr. Biol. 5, 643-650.
25. Francis, P. H., Richardson, M. K., Brickell, P. M. and Tickle, C. (1994). Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb. Development 120, 209-218.
26. Gonzalez, F., Swales, L., Bejsovec, A., Skaer, H. and Martinez Arias, A. (1991). Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. Mech. Dev. 35, 43-54.
27. Heberlein, U., Singh, C. M., Luk, A. Y. and Donohoe, T. J. (1995). Growth and differentiation in the Drosophila eye coordinated by hedgehog [see comments]. Nature 373, 709-11.
28. Heemskerk, J. and DiNardo, S. (1994). Drosophila hedgehog acts as a morphogen in cellular patterning. Cell 76, 449-460.
29. Heemskerk, J., DiNardo, S., Kostriken, R. and O'Farrell, P. H. (1991). Multiple modes of engrailed regulation in the progression towards cell fate determination. Nature 352, 404-410.
30. Hidalgo, A. (1994). Three distinct roles for the engrailed gene in Drosophila wing development. Curr. Biol 4, 1087-1098.
31. Hooper, J. E. and Scott, A. M. P. (1989). The Drosophila patched gene encodes a putative membrane protein required for segmental patterning. Cell 59, 751-765.
32. Ingham, P. W. (1993). Localized hedgehog activity controls spatial limits of Kingless transcription in the Drosophila embryo. Nature 366, 560-562.
33. Ingham, P. W. and Hidalgo, A. (1993). Regulation of wingless transcription in the Drosophila embryo. Development 117, 283-291.
34. Ingham, P., Taylor, A. and Nakano, Y. (1991). Role of the Drosophila patched gene in positional signalling Nature 353, 184-187.
35. Irish, V. F. and Gelbart, W. M. (1987). The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo. Genes Dev. 1, 868-879.
36. Jackson, P. D. and Hoffmann, F. M. (1994). Embryonic expression patterns of the Drosophila decapentaplegic gene: separate regulatory elements control blastoderm expression and lateral ectodermal expression. Dev. Dynam. 199, 28-44.
37. Jiang, J. and Strahl, G. (1995). Protein kinase A and hedgehog signaling in Drosophila limb development. Cell 80, 563-572.
38. Kassis, J. A., Noll, E., VanSickle, E. P., Odenwald, W. F. and Perrimon, N. (1992). Altering the insertional specificity of a Drosophila transposable element. Proc. Natl. Acad. Sci USA 89, 1919-1923.
39. Krauss, S., Concordet, J.-P. and Ingham, P. W. (1993). A functionally conserved homolog of the Drosophila segment polarity gene hedgehog is expressed in tissues with polarising activity in zebrafish embryos. Cell 75, 1431-1444.
40. Lawrence, P. A., Johnston, P., Macdonald, P. and Struhl, G. (1987). Borders of parasegments in Drosophila embryos are delimited by the fushi tarazu and evenskipped genes. Nature 328, 440-442.
41. Lee, J. J., von Kessler, D. P., Parks, S. and Beachy, P. A. (1992). Secreton and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog. Cell 71, 33-50
42. Lee, J. J., Ekker, S. C., von, K. D., Porter, J. A., Sun, B. I. and Beachy, P. A. (1994). Autoproteolysis in hedgehog protein biogenesis [see comments]. Science 266, 1528-1537.
43. Lepage, T., Cohen, S. M., Diaz, B. F. and Parkhurst, S. M. (1995). Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning [see comments]. Nature 373, 711-715.
44. Li. W., Ohlmeyer, J. T., Lane, M. E. and Kalderon, D. (1995). Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development. Cell 80, 553-62.
45. Lindsley, D. L. and Zimm, G. G. (1992). The Genome of Drosophila. New York: Academic Press.
46. Lohs-Schardin, M., Cremer, C. and Nusslein-Volhard, C. (1979). A fate map of the larval epidermis of Drosophila melanogaster: Localized cuticle defects following irradiation of the blastoderm with an ultraviolet laser beam. Dev. Biol. 73,239-255.
47. Marti, E., Bumcrot, D. A., Takada, R. and McMahon, A. P. (1995). Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants [see comments]. Nature 375, 322-5.
48. Martinez Arias, A., Baker, N. E. and Ingham, P. W. (1988). Role of segment polanty genes in the definition and maintenance of cell states in the Drasophila embryo. Development 103, 157-170.
49. McMahon, A. P., Joyner, A. L., Bradley, A. and McMahon, J. A. (1992). The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell 69, 581-595.
50. McMahon, A. P. and Moon, R. T. (1989). Ectopic expression of the protooncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell 58, 1075-1084
51. Mohler, J. (1988). Requirements for hedgehog a segmental polarity gene in patterning larval and adult cuticle of drosophila. Genetics 120, 1061-1072.
52. Mohler, J. and Vani, K. (1992). Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila. Devel. 115, 957-971
53. Nakano, Y., Guerrero, I., Hidalgo, A., Taylor, A., Whittle, J. R. S. and Ingham, P. W. (1989). A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched. Nature 341, 508-513.
54. Nusse, R. and Varmus, H. E. (1992). Wnt genes. [Review]. Cell 69, 1073-1087.
55. Nusslein-Volhard, C. and Wieschaus, E. (1980). Mutations affecting segment number and polarity in Drosophila. Nature 287, 795-801.
56. Padgett, R. W., St. Johnston, R. D. and Gelbart, W. M. (1987). A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming frowth factor-β family. Nature 325, 81-84.
57. Pan, D. and Rubin, G. M. (1995). cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginai discs. Cell 80, 543-552.
58. Patel, N. H., Martin-Blanco, E., Coleman, K. G., Poole, S. J., Ellis, M. C., Kornberg, T. B. and Goodman, C. S. (1989). Expression of engrailed proteins in arthropods annelids and chordates. Cell 58, 955-968.
59. Porter, J. A., von, K. D., Ekker, S. C., Young, K. E., Lee, J. J., Moses, K. and Beachy, P. A. (1995). The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature 374, 363-366.
60. Riddle, R., Johnson, R. L., Laufer, E. and Tabin, C. (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.
61. Rijsewijk, F., Scheurmann, M., Wagenaar, E., Parren, P., Weigel, D. and Nusse, R. (1987). The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell 50, 649-657.
62. Roelink, H., Augsburger, A., Heemskerk, J., Korzh, V., Norlin, S., Ruiz, i, Altaba, A, Tanabe, Y., Placzek, M., Edlund, T., Jessell, T. M. and et, a. l.. (1994). Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76, 761-775.
63. Staehling-Hampton, K., Hoffmann, F. M., Baylies, M. K., Rushton, E. and Bate, M. (1994). dpp induces mesodermal gene expression in Drosophila. Nature 372, 783-786.
64. Struhl, G. and Basler, K. (1993). Organizing activity of wingless protein in Drosophila. Cell 72, 527-540
65. Strutt, D. I., Wiersdorff, V. and Mlodzik, M. (1995). Regulation of furrow progression in the Drosophila eye by cAMP-dependent protein kinase A [see comments] Nature 373, 705-709
66. Tabata, T., S., E. and Kornberg, T. B. (1992). The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation. Genes Dev. 6, 2635-2645.
67. Tabata, T. and Kornberg, T. B. (1994). Hedgehog is a signalling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.
68. Tautz, D. and Peifle, C. (1989) A non-radioactive in situ hybridization method for localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
69. van den Heuvel, M., Klingensmith, J., Perrimon, N. and Nusse, R. (1993). Cell patterning in the Drosophila segment: engrailed and wingless antigen distributions in segment polarity mutant embryos. Development Supplement 105-114.
70. van den Heuvel, M., Nusse, R., Johnston, P. and Lawrence, P. (1989). Distribution of the wingless gene product in Drosophila embryos: A protein involved in cell-cell communication. Cell 59, 739-749.
71. van der Meer, S. (1977). Optical clean and permanent whole mount eparation for phase contrast microscopy of cuticular structures of insect larvae. Dros. Inf. Serv. 52, 160-161.
72. Wharton, K. A., Ray, R. P. and Gelbart, W. M. (1993). An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. Development 117, 807-822.
73. Wharton, K. A., Thomsen, G. H. and Gelbart, W. M. (1991). Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins, Proc. Nat. Acad. Sci. USA 88, 9214-9218.
74. Wieschaus, E. and Nüsslein-Volhard, C. (1986) Looking at embryos in Drosophila: A Practical Approach (ed. D. B. Roberts), pp. 199-227. Oxford: IRL Press.
75. Wieschaus, E. and Riggleman, R. (1987). Autonomous requirements for the segment polarity gene armadillo during Drosophila embryogenesis. Cell 49, 177-184.
76. Wilder, E. and Perrimon, N. (1995). Dual functions of wingless in the Drosophila leg imaginal disc. Development: 121, 477-488.
77. Zecca, M., Basler, K. and Struhl, G. (1995). Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. Development 121, 2265-2278.