Centroblastic and centroblastic-centrocytic lymphomas associated with prominent epithelioid granulomatous response without plasma cell differentiation: A clinicopathologic study of 12 cases

Human Pathology

Volumn 27, Issue 7, 1996, Pages 660-667

  Kojima, Masaru ^a   Nakamura, Shigeo ^b   Motoori, Tadashi ^b   Kurabayashi, Yoshiyuki ^b   Hosomura, Yasuo ^b   Itoh, Hideaki ^b   Yoshida, Katsue ^b   Suzuki, Ritsuro ^b   Seto, Masao ^b   Koshikawa, Takashi ^b   Suchi, Taizan ^b   Joshita, Takashi ^b  

^a ASHIKAGA RED CROSS HOSPITAL   (Japan)

^b NONE

Author keywords

centroblastic lymphoma; centroblastic centrocytic lymphoma; epithelioid granulomatous response

Indexed keywords

PROTEIN BCL 2;

ADULT; AGED; ARTICLE; B CELL LYMPHOMA; CANCER STAGING; CLINICAL ARTICLE; DISEASE CLASSIFICATION; EPSTEIN BARR VIRUS; FEMALE; HISTOPATHOLOGY; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NONHODGKIN LYMPHOMA; PLASMA CELL; T LYMPHOCYTE RECEPTOR GENE; VIRUS GENE;

EID: 15844387504     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(96)90395-0     Document Type: Article

References (40)

1. Lennert K, Mestdagh J: Lymphogranulomatosen mit konstant hohem Epitheloidzellgehalt. Virchows Arch A Pathol Anat 344:1-20, 1968
2. Kadin ME, Donaldson SS, Dorfman RF: Isolated granulomas in Hodgkin's disease. N Engl J Med 283:859-861, 1970
3. Brincker H: Sarcoid reactions and sarcoidosis in Hodgkin's disease and other malignant lymphomata. Br J Cancer 26:120-128, 1972
4. O'Connell MJ, Schimpff SC, Kirschner RH, et al: Epithelioid granulomas in Hodgkin disease: A favorable prognostic sign? JAMA 233:886-889, 1975
5. Patsouris E, Noël H, Lennert K: Cytohistologic and immunohistochemical findings in Hodgkin's disease, mixed cellularity type, with a high content of epithelioid cells. Am J Surg Pathol 13:1014-1022, 1989
6. Bednáň B: Lymphoepitheloid cell malignant lymphoma (Lennert). Virchows Arch A Pathol Anat 382:313-322, 1979
7. Bedetti CD, Ollapally E: Malignant lymphoma with a high content of epithelioid histiocytes (so-called Lennert's lymphoma): Immunocytochemical and ultrastructural observations. Virchows Arch A Pathol Anat 399:255-264, 1983
8. Nanba K, Dohy H, Sasaki N, et al: Malignant lymphoma associated with prominent epithelioid cellular reactions: Clinicopathologic, cytochemical, immunological and electron microscopic study of 19 cases. Byori to Rinsho 3:1119-1129, 1985 (in Japanese)
9. Spier CM, Lippman SM, Miller TP, et al: Lennert's lymphoma: A clinicopathologic study with emphasis on phenotype and its relationship to survival. Cancer 61:517-524, 1988
10. Suchi T, Lennert K, Tu L-Y, et al: Histopathology and immunohistochemistry of peripheral T cell lymphomas: A proposal for their classification. J Clin Pathol 40:995-1015, 1987
11. Patsouris E, Noël H, Lennert K: Histological and immunohistological findings in lymphoepithelioid cell lymphoma (Lennert's lymphoma). Am J Surg Pathol 12:341-350, 1988
12. Nakamura S, Suchi T: A clinicopathologic study of node-based, low-grade, peripheral T-cell lymphoma: Angioimmunoblastic lymphoma, T-zone lymphoma, and lymphoepithelioid lymphoma. Cancer 67:2565-2578, 1991
13. Lennert K, Feller AC: Histopathology of non-Hodgkin's Lymphoma (Based on the Updated Kiel Classification) (ed 2). New York, NY, Springer-Verlag, 1992
14. Miller R, Spicer SS, Kurtz SM: Histiocytic lymphoma in a patient with Lennert's lymphoma: Report of a case with unusual cytoplasmic inclusions. Arch Pathol Lab Med 103:279-283, 1979
15. Mirchandani I, Palutke M, Tabaczka P, et al: B-cell lymphomas morphologically resembling T-cell lymphomas. Cancer 56:1578-1583, 1985
16. Patsouris E, Noël H, Lennert K: Lymphoplasmacytic/lymphoplasmacytoid immunocytoma with a high content of epithelioid cells: Histologic and immunohistochemical findings. Am J Surg Pathol 14:660-670, 1990
17. Macon WR, Williams ME, Creer JP, et al: T-cell-rich B-cell lymphomas: A clinicopathologic study of 19 cases. Am J Surg Pathol 16:351-363, 1992
18. Kim H, Dorfman RF: Morphological studies of 84 untreated patients subjected to laparotomy for the staging of non-Hodgkin's lymphomas. Cancer 33:657-674, 1974
19. Hollingsworth HC, Longo DL, Jaffe ES: Small noncleaved cell lymphoma associated with florid epithelioid granulomatous response: A clinicopathologic study of seven patients. Am J Surg Pathol 17:51-59, 1993
20. Aisenberg AC: Malignant Lymphoma: Biology, Natural History, and Treatment. Malvern, PA, Lea & Febiger, 1991, pp 319-332
21. Ioachim HL: Lymph Node Pathology (ed 2). Philadelphia, PA, Lippicott, 1994
22. Ramsy AD, Smith WJ, Isaacson PG: T-cell-rich B-cell lymphoma. Am J Surg Pathol 12:433-443, 1988
23. Winberg CD, Sheibani K, Burke JS, et al: T-cell-rich lymphoproliferative disorders: Morphological and immunologic differential diagnoses. Cancer 62:1539-1555, 1988
24. Ng CS, Chan JKC, Hui PK, et al: Large B-cell lymphomas with a high content of reactive T cells. HUM PATHOL 20:1145-1154, 1989
25. H rearrangement. Am J Surg Pathol 14:933-938, 1990
26. Chittal SM, Brousset P, Voigt J-J, et al: Large B-cell lymphoma rich in T-cells and simulating Hodgkin's disease. Histopathology 19:211-220, 1991
27. Krishnan J, Wallberg K, Frizzerra G: T-cell-rich large B-cell lymphoma: A study of 30 cases, supporting its histologic heterogeneity and lack of clinical distinctiveness. Am J Surg Pathol 18:455-465, 1994
28. Dalabie J, Vandenberghe E, Kennes C, et al: Histiocyte-rich B-cell lymphoma: A distinct clinicopathologic entity possibly related to lymphocyte predominant Hodgkin's disease, paragranuloma subtype. Am J Surg Pathol 16:37-48, 1992
29. Carbone PP, Kaplan HS, Mussoff K, et al: Report of the committee on Hodgkin's disease staging classification. Cancer Res 31:1860-1861, 1971
30. Osada H, Seto M, Ueda R, et al: bcl-2 gene rearrangement analysis in Japanese B cell lymphoma: Novel bcl-2 recombination with immunoglobulin êchain gene. Jpn J Cancer Res 80:711-715, 1989
31. Seto M, Jaeger U, Hockett RD, et al: Alternative promoters and exons, somatic mutation and deregulation of the bcl-2 Ig fusion gene in lymphoma. EMBO J 7:123-131, 1988
32. Bakhshi A, Wright JJ, Graninger W, et al: Mecanism of the t(14; 18) chromosomal translocation: Structural analysis of both derivative 14 and 18 reciprocal partners. Proc Natl Acad Sci USA 84:2396-2400, 1987
33. Weiss LM, Warnke RA, Sklar J, et al: Molecular analysis of the t(14;18) chromosomal translocation on malignant lymphomas. N Engl J Med 317:1185-1189, 1987
34. Brousset P, Buter V, Chittal S, et al: Comparison of in situ hybridization using different nonisotopic probes for detection of Epstein-Barr virus in nasopharyngeal carcinoma and immunohistochemical correlation with antilatent membrane protein antibody. Lab Invest 67:457-464, 1992
35. Epstein AL, Marder RJ, Winter JN, et al: Two new monoclonal antibodies (LN-1, LN-2) reactive in B5 formalin-fixed paraffin-embedded tissue with follicular center and mantle zone human B lymphocytes and derived tumors. J Immunol 133:1028-1036, 1984
36. Perkins SL, Kjeldesberg CR: Immunophenotyping of lymphomas and leukemias in paraffin-embedded tissues. Am J Clin Pathol 99:362-373, 1993
37. Pezzella F, Gatter KC, Macon DY, et al: Bcl-2 protein expression in follicular lymphomas in absence of 14; 18 translocation. Lancet 336:1510-1511, 1990
38. Pezzella F, Tse AGD, Cordell JL, et al: Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation. Am J Pathol 137:225-232, 1990
39. Anagnostopoulos I, Hummel M, Tiemann M, et al: Frequent presence of latent Epstein-Barr virus infection in lymphoepithelioid cell lymphoma (Lennert's lymphoma). Histopathology 25:331-337, 1994
40. Macon WR, Cousar JB, Waldron JA Jr, et al: Interleukin-4 may contribute to the abundant T-cell reaction and paucity of neoplastic B cells in T-cell-rich B-cell lymphomas. Am J Pathol 141:1031-1036, 1992